Binding of recombinant T cell receptor ligands (RTL) to antigen presenting cells prevents upregulation of CD11b and inhibits T cell activation and transfer of experimental autoimmune encephalomyelitis. (Q34077153)

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English	Binding of recombinant T cell receptor ligands (RTL) to antigen presenting cells prevents upregulation of CD11b and inhibits T cell activation and transfer of experimental autoimmune encephalomyelitis.	scientific article

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5 February 2020

Binding of recombinant T cell receptor ligands (RTL) to antigen presenting cells prevents upregulation of CD11b and inhibits T cell activation and transfer of experimental autoimmune encephalomyelitis (English)

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Halina Offner

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Owen J T McCarty

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Owen J T McCarty

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Lisa Miller

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Sandhya Subramanian

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Thomas Proctor

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Roberto Meza-Romero

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Jianya Huan

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Gregory G Burrows

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Arthur A Vandenbark

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publication date

23 May 2010

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5 February 2020

Journal of Neuroimmunology

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225

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1-2

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52-61

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5 February 2020

Recombinant TCR ligand reverses clinical signs and CNS damage of EAE induced by recombinant human MOG

1 reference

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5 July 2018

Cytokine switch and bystander suppression of autoimmune responses to multiple antigens in experimental autoimmune encephalomyelitis by a single recombinant T-cell receptor ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924959

5 July 2018

Recombinant T cell receptor ligands: immunomodulatory, neuroprotective and neuroregenerative effects suggest application as therapy for multiple sclerosis

1 reference

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5 July 2018

Antigen-specific therapy promotes repair of myelin and axonal damage in established EAE.

1 reference

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5 July 2018

Treatment of passive experimental autoimmune encephalomyelitis in SJL mice with a recombinant TCR ligand induces IL-13 and prevents axonal injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924959

5 July 2018

T-cell hybridoma specific for myelin oligodendrocyte glycoprotein-35-55 peptide produced from HLA-DRB1*1501-transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924959

5 July 2018

Lipopolysaccharide enhances FcgammaR-dependent functions in vivo through CD11b/CD18 up-regulation

1 reference

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5 July 2018

Two-domain MHC class II molecules form stable complexes with myelin basic protein 69-89 peptide that detect and inhibit rat encephalitogenic T cells and treat experimental autoimmune encephalomyelitis

1 reference

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5 July 2018

Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis

1 reference

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5 July 2018

A promising therapeutic approach for multiple sclerosis: recombinant T-cell receptor ligands modulate experimental autoimmune encephalomyelitis by reducing interleukin-17 production and inhibiting migration of encephalitogenic cells into the CNS.

1 reference

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28 October 2018

Monomeric recombinant TCR ligand reduces relapse rate and severity of experimental autoimmune encephalomyelitis in SJL/J mice through cytokine switch.

1 reference

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28 October 2018

Recombinant TCR ligand induces early TCR signaling and a unique pattern of downstream activation

1 reference

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28 October 2018

Recombinant TCR ligand induces tolerance to myelin oligodendrocyte glycoprotein 35-55 peptide and reverses clinical and histological signs of chronic experimental autoimmune encephalomyelitis in HLA-DR2 transgenic mice.

1 reference

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28 October 2018

Ligand recognition by alpha beta T cell receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924959

28 October 2018

Design, engineering and production of functional single-chain T cell receptor ligands

1 reference

https://pubmed.ncbi.nlm.nih.gov/20546940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Critical requirement of CD11b (Mac-1) on T cells and accessory cells for development of experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20546940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel flow cytometric assay of human whole blood neutrophil and monocyte CD11b levels: Upregulation by chemokines is related to receptor expression, comparison with neutrophil shape change, and effects of a chemokine receptor (CXCR2) antagonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/20546940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monomeric DR2/MOG-35-55 recombinant TCR ligand treats relapses of experimental encephalomyelitis in DR2 transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20546940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rudimentary TCR signaling triggers default IL-10 secretion by human Th1 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20546940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Both anti-CD11a (LFA-1) and anti-CD11b (MAC-1) therapy delay the onset and diminish the severity of experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20546940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of macrophages, perivascular cells, and microglial cells in the pathogenesis of experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20546940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.JNEUROIM.2010.04.013

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5 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20546940%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

Europe PubMed Central

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5 February 2020

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