Inhibition of the mitotic kinesin Eg5 up-regulates Hsp70 through the phosphatidylinositol 3-kinase/Akt pathway in multiple myeloma cells (Q34515624)

2 August 2017

Inhibition of the mitotic kinesin Eg5 up-regulates Hsp70 through the phosphatidylinositol 3-kinase/Akt pathway in multiple myeloma cells (English)

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2 August 2017

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Jun Zhou

11

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Jin-Tang Dong

object named as

Jin-Tang Dong

7

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Min Liu

1

object named as

Min Liu

1 reference

2 August 2017

Ritu Aneja

2

1 reference

2 August 2017

Chunyong Liu

3

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2 August 2017

Lei Sun

4

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2 August 2017

Jinmin Gao

5

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2 August 2017

Hongxia Wang

6

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2 August 2017

Vasiliki Sarli

8

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2 August 2017

Athanassios Giannis

9

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2 August 2017

Harish C Joshi

10

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2 August 2017

language of work or name

English

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publication date

20 April 2006

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Journal of Biological Chemistry

2 August 2017

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2 August 2017

281

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2 August 2017

26

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2 August 2017

18090-18097

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Attachment and tension in the spindle assembly checkpoint

2 August 2017

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https://api.crossref.org/works/10.1074%2FJBC.M601324200

Microtubule-interacting drugs for cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Microtubules as a target for anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Targeting microtubules for cancer chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

THE DEVELOPMENT AND CLINICAL UTILITY OF THE TAXANE CLASS OF ANTIMICROTUBULE CHEMOTHERAPY AGENTS

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Mitotic spindle organization by a plus-end-directed microtubule motor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Two Saccharomyces cerevisiae kinesin-related gene products required for mitotic spindle assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

The kinesin-like protein KLP61F is essential for mitosis in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Mutation of a gene that encodes a kinesin-like protein blocks nuclear division in A. nidulans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

A model for the proposed roles of different microtubule-based motor proteins in establishing spindle bipolarity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

HR22C16: a potent small-molecule probe for the dynamics of cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Antitumor activity of a kinesin inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Development and biological evaluation of potent and specific inhibitors of mitotic Kinesin Eg5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Suppression of Akt signaling induces Fas ligand expression: involvement of caspase and Jun kinase activation in Akt-mediated Fas ligand regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Increased expression of the major heat shock protein Hsp72 in human prostate carcinoma cells is dispensable for their viability but confers resistance to a variety of anticancer agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Hsp72-mediated suppression of c-Jun N-terminal kinase is implicated in development of tolerance to caspase-independent cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Survivin deregulation in beta-tubulin mutant ovarian cancer cells underlies their compromised mitotic response to taxol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Minor alteration of microtubule dynamics causes loss of tension across kinetochore pairs and activates the spindle checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Drug-resistant T-lymphoid tumors undergo apoptosis selectively in response to an antimicrotubule agent, EM011.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Genomic mechanisms of p210BCR-ABL signaling: induction of heat shock protein 70 through the GATA response element confers resistance to paclitaxel-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Paclitaxel-resistant human ovarian cancer cells undergo c-Jun NH2-terminal kinase-mediated apoptosis in response to noscapine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Reversal of P-glycoprotein-mediated multidrug resistance in cancer cells by the c-Jun NH2-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Two transcriptional activators, CCAAT-box-binding transcription factor and heat shock transcription factor, interact with a human hsp70 gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Signal transducer and activator of transcription-1 and heat shock factor-1 interact and activate the transcription of the Hsp-70 and Hsp-90beta gene promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Differential activation of p38 mitogen-activated protein kinase and extracellular signal-regulated protein kinases confers cadmium-induced HSP70 expression in 9L rat brain tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

p38 kinase activity is essential for osmotic induction of mRNAs for HSP70 and transporter for organic solute betaine in Madin-Darby canine kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Akt/FOXO3a signaling modulates the endothelial stress response through regulation of heat shock protein 70 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Heat shock protein-70 mediates the cytoprotective effect of carbon monoxide: involvement of p38 beta MAPK and heat shock factor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Negative regulation of the Apaf-1 apoptosome by Hsp70

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Heat-shock protein 70 antagonizes apoptosis-inducing factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Heat shock protein hsp72 is a negative regulator of apoptosis signal-regulating kinase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Mitotic kinesin inhibitors induce mitotic arrest and cell death in Taxol-resistant and -sensitive cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Thrombin regulates vascular smooth muscle cell growth and heat shock proteins via the JAK-STAT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Effects of antineoplastic agents on cytoplasmic and membrane-bound heat shock protein 70 (Hsp70) levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

Metabolic oxidative stress-induced HSP70 gene expression is mediated through SAPK pathway. Role of Bcl-2 and c-Jun NH2-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601324200

21 January 2018

Identifiers

DOI

10.1074/JBC.M601324200

1 reference

2 August 2017

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