Structure and mechanism of cysteine peptidase gingipain K (Kgp), a major virulence factor of Porphyromonas gingivalis in periodontitis. (Q34509866)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25266723%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

Structure and mechanism of cysteine peptidase gingipain K (Kgp), a major virulence factor of Porphyromonas gingivalis in periodontitis (English)

1 reference

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20 February 2020

main subject

Porphyromonas gingivalis

0 references

0 references

1

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20 February 2020

F. Xavier Gomis-Rüth

9

1 reference

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20 February 2020

8

Jan Potempa

1 reference

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20 February 2020

5

Barbara Potempa

1 reference

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20 February 2020

author name string

Florian Veillard

2

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20 February 2020

Maryta N Sztukowska

3

1 reference

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20 February 2020

Tibisay Guevara

4

1 reference

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20 February 2020

Anja Pomowski

6

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20 February 2020

James A Huntington

7

1 reference

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20 February 2020

language of work or name

English

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publication date

29 September 2014

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Journal of Biological Chemistry

20 February 2020

published in

1 reference

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20 February 2020

volume

289

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20 February 2020

issue

46

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20 February 2020

page(s)

32291-32302

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Anti-inflammatory Actions of Adjunctive Tetracyclines and Other Agents in Periodontitis and Associated Comorbidities

20 February 2020

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A systematic review on the effects of local antimicrobials as adjuncts to subgingival debridement, compared with subgingival debridement alone, in the treatment of chronic periodontitis.

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Kgp and RgpB, but not RgpA, are important for Porphyromonas gingivalis virulence in the murine periodontitis model.

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Acquisition of iron from human transferrin by Porphyromonas gingivalis: a role for Arg- and Lys-gingipain activities

7 July 2018

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Structural and biochemical features distinguish the foot-and-mouth disease virus leader proteinase from other papain-like enzymes

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Identification of the active site of legumain links it to caspases, clostripain and gingipains in a new clan of cysteine endopeptidases

7 July 2018

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7 July 2018

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7 July 2018

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Titration and mapping of the active site of cysteine proteinases from Porphyromonas gingivalis (gingipains) using peptidyl chloromethanes

7 July 2018

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7 July 2018

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Porphyromonas gingivalis proteinases in periodontitis, a review

7 July 2018

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Lysine- and arginine-specific proteinases from Porphyromonas gingivalis. Isolation, characterization, and evidence for the existence of complexes with hemagglutinins

7 July 2018

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Buried waters and internal cavities in monomeric proteins

7 July 2018

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Crystal structures of recombinant rat cathepsin B and a cathepsin B-inhibitor complex. Implications for structure-based inhibitor design

7 July 2018

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The multiple forms of trypsin-like activity present in various strains of Porphyromonas gingivalis are due to the presence of either Arg-gingipain or Lys-gingipain

7 July 2018

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The anatomy and taxonomy of protein structure

7 July 2018

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On the size of the active site in proteases. I. Papain

7 July 2018

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Solvent content of protein crystals

7 July 2018

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Multiple sequence alignment with hierarchical clustering

7 July 2018

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The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment

7 July 2018

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Purification and characterization of a 50-kDa cysteine proteinase (gingipain) from Porphyromonas gingivalis

7 July 2018

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The alpha/beta hydrolase fold

7 July 2018

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Binding of chloromethyl ketone substrate analogues to crystalline papain

7 July 2018

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Drug development: Time for teamwork

7 July 2018

1 reference

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The pathobiology of periodontal diseases may affect systemic diseases: inversion of a paradigm.

21 January 2018

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The Entropic Cost of Bound Water in Crystals and Biomolecules

21 January 2018

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The C-terminal domains of the gingipain K polyprotein are necessary for assembly of the active enzyme and expression of associated activities

21 January 2018

1 reference

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Determination of active site of lysine-specific cysteine proteinase (Lys-gingipain) by use of a Porphyromonas gingivalis plasmid system

21 January 2018

1 reference

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Hydrophilicity of cavities in proteins

21 January 2018

1 reference

12 December 2020

Metal-ligand geometry relevant to proteins and in proteins: sodium and potassium

1 reference

12 December 2020

Cleavage of human complement component C5 by cysteine proteinases from Porphyromonas (Bacteroides) gingivalis. Prior oxidation of C5 augments proteinase digestion of C5

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12 December 2020

An x-ray crystallographic study of the binding of peptide chloromethyl ketone inhibitors to subtilisin BPN'

1 reference

12 December 2020

Serine protease inhibitors N-alpha-tosyl-L-lysinyl-chloromethylketone (TLCK) and N-tosyl-L-phenylalaninyl-chloromethylketone (TPCK) are potent inhibitors of activated caspase proteases

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M114.602052

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25266723%20AND%20SRC:MED&resulttype=core&format=json

release_himfzkkxtrb5zdfjk6g4ceqkam

20 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/himfzkkxtrb5zdfjk6g4ceqkam

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25266723%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference