Regulation of endogenous ENaC functional expression by CFTR and ΔF508-CFTR in airway epithelial cells. (Q34502195)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20935229%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

title

Regulation of endogenous ENaC functional expression by CFTR and ΔF508-CFTR in airway epithelial cells (English)

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15 February 2020

1

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15 February 2020

author name string

Shannon R Lockwood

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20935229%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Ellen Lide

3

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15 February 2020

Rebecca Bauer

4

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15 February 2020

Laurence Suaud

5

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15 February 2020

Yael Grumbach

6

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15 February 2020

language of work or name

1 reference

8 October 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20935229%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Physiology - Lung Cellular and Molecular Physiology

15 February 2020

published in

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15 February 2020

volume

300

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15 February 2020

issue

1

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15 February 2020

page(s)

L88-L101

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Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770

15 February 2020

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7 July 2018

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7 July 2018

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Serine protease activation of near-silent epithelial Na+ channels

7 July 2018

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Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion.

7 July 2018

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Synergistic activation of ENaC by three membrane-bound channel-activating serine proteases (mCAP1, mCAP2, and mCAP3) and serum- and glucocorticoid-regulated kinase (Sgk1) in Xenopus Oocytes

7 July 2018

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Evidence of CFTR function in cystic fibrosis after systemic administration of 4-phenylbutyrate

7 July 2018

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Glucocorticoid-stimulated lung epithelial Na(+) transport is associated with regulated ENaC and sgk1 expression

7 July 2018

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Genistein restores functional interactions between Delta F508-CFTR and ENaC in Xenopus oocytes

7 July 2018

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Regulation of the epithelial sodium channel by serine proteases in human airways

7 July 2018

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Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression

7 July 2018

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Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel

7 July 2018

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7 July 2018

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Sodium 4-phenylbutyrate downregulates HSC70 expression by facilitating mRNA degradation

7 July 2018

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7 July 2018

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7 July 2018

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Expression of highly selective sodium channels in alveolar type II cells is determined by culture conditions

7 July 2018

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Cystic fibrosis transmembrane conductance regulator facilitates ATP release by stimulating a separate ATP release channel for autocrine control of cell volume regulation

7 July 2018

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Activation of the epithelial Na+ channel (ENaC) requires CFTR Cl- channel function

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Cl- transport by cystic fibrosis transmembrane conductance regulator (CFTR) contributes to the inhibition of epithelial Na+ channels (ENaCs) in Xenopus oocytes co-expressing CFTR and ENaC.

7 July 2018

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In vitro pharmacologic restoration of CFTR-mediated chloride transport with sodium 4-phenylbutyrate in cystic fibrosis epithelial cells containing delta F508-CFTR.

7 July 2018

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An epithelial serine protease activates the amiloride-sensitive sodium channel

7 July 2018

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Cystic fibrosis transmembrane conductance regulator inverts protein kinase A-mediated regulation of epithelial sodium channel single channel kinetics

7 July 2018

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Role of actin in regulation of epithelial sodium channels by CFTR.

7 July 2018

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Inhibition of epithelial Na+ currents by intracellular domains of the cystic fibrosis transmembrane conductance regulator.

7 July 2018

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Expression of the cystic fibrosis phenotype in a renal amphibian epithelial cell line

7 July 2018

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Regulation of epithelial Na+ channels from M-1 cortical collecting duct cells

7 July 2018

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Wild type but not deltaF508 CFTR inhibits Na+ conductance when coexpressed in Xenopus oocytes.

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Modulation of epithelial sodium channel trafficking and function by sodium 4-phenylbutyrate in human nasal epithelial cells

27 October 2018

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Regulatory interactions of N1303K-CFTR and ENaC in Xenopus oocytes: evidence that chloride transport is not necessary for inhibition of ENaC.

27 October 2018

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Airway surface liquid volume regulates ENaC by altering the serine protease-protease inhibitor balance: a mechanism for sodium hyperabsorption in cystic fibrosis.

27 October 2018

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Abnormal regulatory interactions of I148T-CFTR and the epithelial Na+ channel in Xenopus oocytes.

27 October 2018

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Differential modulation of a polymorphism in the COOH terminus of the alpha-subunit of the human epithelial sodium channel by protein kinase Cdelta.

27 October 2018

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CFTR fails to inhibit the epithelial sodium channel ENaC expressed in Xenopus laevis oocytes.

27 October 2018

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27 October 2018

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27 October 2018

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27 October 2018

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27 October 2018

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The cytosolic termini of the beta- and gamma-ENaC subunits are involved in the functional interactions between cystic fibrosis transmembrane conductance regulator and epithelial sodium channel.

27 October 2018

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27 October 2018

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Downregulation of epithelial sodium channel (ENaC) by CFTR co-expressed in Xenopus oocytes is independent of Cl- conductance.

27 October 2018

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Cystic fibrosis transmembrane conductance regulator inhibits epithelial Na+ channels carrying Liddle's syndrome mutations.

27 October 2018

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The activity of the epithelial sodium channel is regulated by clathrin-mediated endocytosis.

27 October 2018

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27 October 2018

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Antisense oligonucleotides against the alpha-subunit of ENaC decrease lung epithelial cation-channel activity

27 October 2018

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A pilot clinical trial of oral sodium 4-phenylbutyrate (Buphenyl) in deltaF508-homozygous cystic fibrosis patients: partial restoration of nasal epithelial CFTR function

9 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20935229

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Sodium 4-phenylbutyrate downregulates Hsc70: implications for intracellular trafficking of DeltaF508-CFTR

1 reference

PubMed

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identification of nonselective cation channels in cultured adult rat alveolar type II cells

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inferred from PubMed ID database lookup

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Identifiers

DOI

10.1152/AJPLUNG.00142.2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20935229%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20935229%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference