Cannabidiol as a Potential Treatment for Anxiety Disorders (Q34492624)

2 August 2017

Cannabidiol as a Potential Treatment for Anxiety Disorders (English)

1 reference

2 August 2017

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Jorge Manzanares

3

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author name string

Esther M Blessing

series ordinal

1

1 reference

PubMed ID

26341731

2 August 2017

Maria M Steenkamp

series ordinal

2

1 reference

PubMed ID

26341731

2 August 2017

Charles R Marmar

series ordinal

4

1 reference

2 August 2017

4 September 2015

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2 August 2017

1 reference

2 August 2017

12

1 reference

2 August 2017

4

1 reference

2 August 2017

825-836

1 reference

https://scigraph.springernature.com/pub.10.1007/s13311-015-0387-1

2 August 2017

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Cannabidiol: pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders

6 July 2018

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PTSD symptom reports of patients evaluated for the New Mexico Medical Cannabis Program

6 July 2018

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Modulation of defensive behavior by Transient Receptor Potential Vanilloid Type-1 (TRPV1) channels.

6 July 2018

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A critical role for prefrontocortical endocannabinoid signaling in the regulation of stress and emotional behavior.

6 July 2018

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Effects of intra-prelimbic prefrontal cortex injection of cannabidiol on anxiety-like behavior: involvement of 5HT1A receptors and previous stressful experience

6 July 2018

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Does Cannabidiol Protect Against Adverse Psychological Effects of THC?

6 July 2018

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Inhibitory neural activity predicts response to cognitive-behavioral therapy for posttraumatic stress disorder

6 July 2018

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The role of 5-HT1A receptors in the anti-aversive effects of cannabidiol on panic attack-like behaviors evoked in the presence of the wild snake Epicrates cenchria crassus (Reptilia, Boidae).

6 July 2018

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Cannabinoids and schizophrenia: therapeutic prospects

6 July 2018

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Serotonin 5-HT1A receptors as targets for agents to treat psychiatric disorders: rationale and current status of research.

6 July 2018

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The endocannabinoid system in energy homeostasis and the etiopathology of metabolic disorders

6 July 2018

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Cannabinoids ameliorate impairments induced by chronic stress to synaptic plasticity and short-term memory

6 July 2018

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The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system

6 July 2018

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Endocannabinoid system and mood disorders: priming a target for new therapies

6 July 2018

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Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders

6 July 2018

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Endocannabinoid signaling and synaptic function

6 July 2018

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Mitigation of post-traumatic stress symptoms by Cannabis resin: a review of the clinical and neurobiological evidence

6 July 2018

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Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug

6 July 2018

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Acute effects of a single, oral dose of d9-tetrahydrocannabinol (THC) and cannabidiol (CBD) administration in healthy volunteers

6 July 2018

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On disruption of fear memory by reconsolidation blockade: evidence from cannabidiol treatment

6 July 2018

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The endocannabinoid system: an overview

6 July 2018

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Fear relief-toward a new conceptual frame work and what endocannabinoids gotta do with it.

6 July 2018

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Safety and side effects of cannabidiol, a Cannabis sativa constituent

6 July 2018

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Anxiogenic-like effects of chronic cannabidiol administration in rats

6 July 2018

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Endocannabinoid system and psychiatry: in search of a neurobiological basis for detrimental and potential therapeutic effects

6 July 2018

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Cost of disorders of the brain in Europe 2010.

6 July 2018

1 reference

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Anti-aversive effects of cannabidiol on innate fear-induced behaviors evoked by an ethological model of panic attacks based on a prey vs the wild snake Epicrates cenchria crassus confrontation paradigm

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604171

Cannabinoid type 1 receptors and transient receptor potential vanilloid type 1 channels in fear and anxiety-two sides of one coin?

6 July 2018

1 reference

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Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus

6 July 2018

1 reference

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Adjunctive risperidone treatment for antidepressant-resistant symptoms of chronic military service-related PTSD: a randomized trial

6 July 2018

1 reference

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The endocannabinoid system in anxiety, fear memory and habituation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604171

Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604171

Diminished gray matter in the hippocampus of cannabis users: possible protective effects of cannabidiol

6 July 2018

1 reference

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Dissociable roles of prelimbic and infralimbic cortices, ventral hippocampus, and basolateral amygdala in the expression and extinction of conditioned fear

6 July 2018

1 reference

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Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study: naturalistic study [corrected].

6 July 2018

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Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report

6 July 2018

1 reference

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Fast feedback inhibition of the HPA axis by glucocorticoids is mediated by endocannabinoid signaling.

6 July 2018

1 reference

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Cannabidiol attenuates the appetitive effects of Delta 9-tetrahydrocannabinol in humans smoking their chosen cannabis

6 July 2018

1 reference

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Opposite effects of delta-9-tetrahydrocannabinol and cannabidiol on human brain function and psychopathology

6 July 2018

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A behavioural comparison of acute and chronic Delta9-tetrahydrocannabinol and cannabidiol in C57BL/6JArc mice

6 July 2018

1 reference

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Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb

6 July 2018

1 reference

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Selective participation of the bed nucleus of the stria terminalis and CRF in sustained anxiety-like versus phasic fear-like responses

6 July 2018

1 reference

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Hot flash: TRPV channels in the brain.

6 July 2018

1 reference

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Interactions between environmental aversiveness and the anxiolytic effects of enhanced cannabinoid signaling by FAAH inhibition in rats.

6 July 2018

1 reference

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Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604171

5-HT1A receptors are involved in the cannabidiol-induced attenuation of behavioural and cardiovascular responses to acute restraint stress in rats

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604171

Distinct effects of {delta}9-tetrahydrocannabinol and cannabidiol on neural activation during emotional processing

6 July 2018

1 reference

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Involvement of 5HT1A receptors in the anxiolytic-like effects of cannabidiol injected into the dorsolateral periaqueductal gray of rats

6 July 2018

1 reference

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The endocannabinoid system: emotion, learning and addiction

6 July 2018

1 reference

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Effects of cannabidiol on schizophrenia-like symptoms in people who use cannabis

6 July 2018

1 reference

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Cannabidiol--recent advances

6 July 2018

1 reference

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Quality of life in the anxiety disorders: a meta-analytic review

6 July 2018

1 reference

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Azapirones for generalized anxiety disorder

6 July 2018

1 reference

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Agonistic properties of cannabidiol at 5-HT1a receptors

6 July 2018

1 reference

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Lifetime Prevalence and Age-of-Onset Distributions of DSM-IV Disorders in the National Comorbidity Survey Replication

6 July 2018

1 reference

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Endocannabinoid system and stress and anxiety responses.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604171

Memory reconsolidation and extinction have distinct temporal and biochemical signatures.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604171

Effects of cannabidiol (CBD) on regional cerebral blood flow

6 July 2018

1 reference

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Endocannabinoid signaling in the brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604171

6 July 2018

Modeling panic attacks

1 reference

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Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide

6 July 2018

1 reference

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Anandamide: some like it hot.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604171

Columnar organization in the midbrain periaqueductal gray: modules for emotional expression?

6 July 2018

1 reference

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Action of cannabidiol on the anxiety and other effects produced by delta 9-THC in normal subjects

6 July 2018

1 reference

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Sensations Evoked by Stimulation in the Midbrain of Man

6 July 2018

1 reference

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Cannabidiol interferes with the effects of Δ9-tetrahydrocannabinol in man

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604171

Electrophysiological responses of serotoninergic dorsal raphe neurons to 5-HT1A and 5-HT1B agonists

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604171

Pharmacological characterization of cannabinoids in the elevated plus maze

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604171

Antianxiety effect of cannabidiol in the elevated plus-maze

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604171

Anxiety disorders in primary care: prevalence, impairment, comorbidity, and detection.

6 July 2018

1 reference

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Suicide risk in patients with anxiety disorders: a meta-analysis of the FDA database.

21 January 2018

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Twelve-month use of mental health services in the United States: results from the National Comorbidity Survey Replication.

21 January 2018

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An effect-size analysis of the relative efficacy and tolerability of serotonin selective reuptake inhibitors for panic disorder.

21 January 2018

1 reference

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Associations of psychotherapy dose and SSRI or SNRI refills with mental health outcomes among veterans with PTSD.

21 January 2018

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The endogenous cannabinoid system controls extinction of aversive memories

21 January 2018

1 reference

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Downregulation of endocannabinoid signaling in the hippocampus following chronic unpredictable stress

21 January 2018

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The endocannabinoid system provides an avenue for evidence-based treatment development for PTSD.

21 January 2018

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Role in anxiety behavior of the endocannabinoid system in the prefrontal cortex

21 January 2018

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Cooperative regulation of anxiety and panic-related defensive behaviors in the rat periaqueductal grey matter by 5-HT1A and μ-receptors.

21 January 2018

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Activation of postsynaptic 5-HT1A receptors improve stress adaptation

21 January 2018

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Facilitation of fear extinction by the 5-HT(1A) receptor agonist tandospirone: possible involvement of dopaminergic modulation.

21 January 2018

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Activation of 5-HT₁A receptors in the medial subdivision of the central nucleus of the amygdala produces anxiolytic effects in a rat model of Parkinson's disease.

21 January 2018

1 reference

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Anxiolytic-like effect of cannabidiol in the rat Vogel conflict test.

21 January 2018

1 reference

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Effects of cannabidiol and diazepam on behavioral and cardiovascular responses induced by contextual conditioned fear in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-015-0387-1

Facilitation of contextual fear memory extinction and anti-anxiogenic effects of AM404 and cannabidiol in conditioned rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-015-0387-1

Evidence for a potential role for TRPV1 receptors in the dorsolateral periaqueductal gray in the attenuation of the anxiolytic effects of cannabinoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-015-0387-1

Intra-dorsal periaqueductal gray administration of cannabidiol blocks panic-like response by activating 5-HT1A receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-015-0387-1

Involvement of the prelimbic prefrontal cortex on cannabidiol-induced attenuation of contextual conditioned fear in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-015-0387-1

Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-015-0387-1

The anxiolytic-like effects of cannabidiol injected into the bed nucleus of the stria terminalis are mediated by 5-HT1A receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-015-0387-1

Effects of intracisternal administration of cannabidiol on the cardiovascular and behavioral responses to acute restraint stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-015-0387-1

Effect of cannabidiol on sleep disruption induced by the repeated combination tests consisting of open field and elevated plus-maze in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-015-0387-1

Cannabidiol injected into the bed nucleus of the stria terminalis reduces the expression of contextual fear conditioning via 5-HT1A receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-015-0387-1

Infusion of cannabidiol into infralimbic cortex facilitates fear extinction via CB1 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-015-0387-1

Involvement of serotonin-mediated neurotransmission in the dorsal periaqueductal gray matter on cannabidiol chronic effects in panic-like responses in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-015-0387-1

Cannabidiol administration into the bed nucleus of the stria terminalis alters cardiovascular responses induced by acute restraint stress through 5-HT₁A receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-015-0387-1

Dissociation between the panicolytic effect of cannabidiol microinjected into the substantia nigra, pars reticulata, and fear-induced antinociception elicited by bicuculline administration in deep layers of the superior colliculus: The role of CB1-c

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-015-0387-1

Cannabidiol enhances consolidation of explicit fear extinction in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-015-0387-1

Neural basis of Delta-9-tetrahydrocannabinol and cannabidiol: effects during response inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-015-0387-1

Modulation of effective connectivity during emotional processing by Delta 9-tetrahydrocannabinol and cannabidiol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-015-0387-1

Mapping motor inhibition: conjunctive brain activations across different versions of go/no-go and stop tasks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-015-0387-1

Neurocircuitry models of posttraumatic stress disorder and beyond: a meta-analysis of functional neuroimaging studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-015-0387-1

Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ⁹-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive-compulsiv

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604171

Remission rates in patients with anxiety disorders treated with paroxetine.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604171

Characteristics of the stimulus produced by the mixture of cannabidiol with delta 9-tetrahydrocannabinol

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604171

Cannabidiol blocks long-lasting behavioral consequences of predator threat stress: possible involvement of 5HT1A receptors

27 October 2018

1 reference

12 December 2020

Cannabidiol reverses the mCPP-induced increase in marble-burying behavior

1 reference

12 December 2020

Cannabidiol exhibits anxiolytic but not antipsychotic property evaluated in the social interaction test

1 reference

12 December 2020

Effects of ipsapirone and cannabidiol on human experimental anxiety

1 reference

12 December 2020

10.1007/S13311-015-0387-1

Identifiers

DOI

1 reference

2 August 2017

1 reference

2 August 2017

1 reference

PubMed ID

26341731