Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders (Q24623179)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23108553%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders (English)

1 reference

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16 February 2020

0 references

0 references

3

1 reference

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16 February 2020

Elaine Del-Bel

4

1 reference

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16 February 2020

Elaine Del Bel

5

1 reference

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16 February 2020

author name string

Alline Cristina Campos

1

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16 February 2020

Fabricio Araújo Moreira

2

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16 February 2020

Francisco Silveira Guimarães

6

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16 February 2020

language of work or name

English

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publication date

1 December 2012

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Philosophical Transactions of the Royal Society B

16 February 2020

published in

1 reference

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16 February 2020

volume

367

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16 February 2020

page(s)

3364-3378

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16 February 2020

issue

1607

1 reference

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Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia

16 February 2020

cites work

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5-HT1A receptors are involved in the cannabidiol-induced attenuation of behavioural and cardiovascular responses to acute restraint stress in rats

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Cannabidiol reduces Aβ-induced neuroinflammation and promotes hippocampal neurogenesis through PPARγ involvement

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Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide

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Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide

7 April 2017

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7 April 2017

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Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants

7 April 2017

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The cloned capsaicin receptor integrates multiple pain-producing stimuli

7 April 2017

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The molecular logic of endocannabinoid signalling

7 April 2017

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On disruption of fear memory by reconsolidation blockade: evidence from cannabidiol treatment

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Distinct neurobehavioural effects of cannabidiol in transmembrane domain neuregulin 1 mutant mice

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Anti-aversive effects of cannabidiol on innate fear-induced behaviors evoked by an ethological model of panic attacks based on a prey vs the wild snake Epicrates cenchria crassus confrontation paradigm

27 September 2017

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27 September 2017

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27 September 2017

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Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report

27 September 2017

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Cannabidiol ameliorates cognitive and motor impairments in bile-duct ligated mice via 5-HT1A receptor activation

27 September 2017

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The therapeutic potential of the endocannabinoid system for the development of a novel class of antidepressants

27 September 2017

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Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb

27 September 2017

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27 September 2017

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Cannabidiol attenuates cisplatin-induced nephrotoxicity by decreasing oxidative/nitrosative stress, inflammation, and cell death

27 September 2017

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That warm fuzzy feeling: brain serotonergic neurons and the regulation of emotion

27 September 2017

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Cannabidiol for the treatment of psychosis in Parkinson's disease

27 September 2017

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Mediation of cannabidiol anti-inflammation in the retina by equilibrative nucleoside transporter and A2A adenosine receptor

27 September 2017

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TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons

27 September 2017

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27 September 2017

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Effects of cannabidiol on schizophrenia-like symptoms in people who use cannabis

27 September 2017

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Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8.

27 September 2017

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Cannabis, the mind and society: the hash realities

27 September 2017

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Cannabidiol in vivo blunts beta-amyloid induced neuroinflammation by suppressing IL-1beta and iNOS expression

27 September 2017

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Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption

27 September 2017

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Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro

27 September 2017

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Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus

27 September 2017

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Inhibition of an equilibrative nucleoside transporter by cannabidiol: a mechanism of cannabinoid immunosuppression

27 September 2017

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Glutamate-modulating drugs as novel pharmacotherapeutic agents in the treatment of obsessive-compulsive disorder

27 September 2017

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Cannabidiol inhibits inducible nitric oxide synthase protein expression and nitric oxide production in beta-amyloid stimulated PC12 neurons through p38 MAP kinase and NF-kappaB involvement

27 September 2017

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Agonistic properties of cannabidiol at 5-HT1a receptors

27 September 2017

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Cannabidiol reverses MK-801-induced disruption of prepulse inhibition in mice

27 September 2017

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Chronic mild stress (CMS) revisited: consistency and behavioural-neurobiological concordance in the effects of CMS.

27 September 2017

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TRP channels: a TR(I)P through a world of multifunctional cation channels

27 September 2017

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Cannabidiol prevents cerebral infarction via a serotonergic 5-hydroxytryptamine1A receptor-dependent mechanism

27 September 2017

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How antipsychotics become anti-"psychotic"--from dopamine to salience to psychosis

27 September 2017

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Effects of cannabidiol (CBD) on regional cerebral blood flow

27 September 2017

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Assessing antidepressant activity in rodents: recent developments and future needs

27 September 2017

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New dawn of cannabinoid pharmacology

27 September 2017

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Action of cannabidiol on the anxiety and other effects produced by delta 9-THC in normal subjects

27 September 2017

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Evidence that cannabidiol does not significantly alter the pharmacokinetics of tetrahydrocannabinol in man

27 September 2017

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Antianxiety effect of cannabidiol in the elevated plus-maze

27 September 2017

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A behavioural comparison of acute and chronic Delta9-tetrahydrocannabinol and cannabidiol in C57BL/6JArc mice

27 September 2017

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Anxiolytic-like effects of AP7 injected into the dorsolateral or ventrolateral columns of the periaqueductal gray of rats

30 May 2018

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Antipsychotic effect of cannabidiol.

30 May 2018

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Cannabidiol interferes with the effects of Δ9-tetrahydrocannabinol in man

30 May 2018

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Pharmacological characterization of cannabinoids in the elevated plus maze

30 May 2018

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Neuroleptics increase c-fos expression in the forebrain: contrasting effects of haloperidol and clozapine

30 May 2018

1 reference

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Influence of cannabidiol on delta-9-tetrahydrocannabinol effects

30 May 2018

1 reference

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Anxiolytic-like effect of cannabidiol in the rat Vogel conflict test.

30 May 2018

1 reference

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Effects of cannabidiol and diazepam on behavioral and cardiovascular responses induced by contextual conditioned fear in rats.

21 January 2018

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Effects of intracisternal administration of cannabidiol on the cardiovascular and behavioral responses to acute restraint stress.

21 January 2018

1 reference

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Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors

21 January 2018

1 reference

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Facilitation of contextual fear memory extinction and anti-anxiogenic effects of AM404 and cannabidiol in conditioned rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Intra-dorsal periaqueductal gray administration of cannabidiol blocks panic-like response by activating 5-HT1A receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

The anxiolytic-like effects of cannabidiol injected into the bed nucleus of the stria terminalis are mediated by 5-HT1A receptors.

21 January 2018

1 reference

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Cannabidiol injected into the bed nucleus of the stria terminalis reduces the expression of contextual fear conditioning via 5-HT1A receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Involvement of the prelimbic prefrontal cortex on cannabidiol-induced attenuation of contextual conditioned fear in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Effect of cannabidiol on sleep disruption induced by the repeated combination tests consisting of open field and elevated plus-maze in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Modulation of effective connectivity during emotional processing by Delta 9-tetrahydrocannabinol and cannabidiol

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Delta9-tetrahydrocannabinol and cannabidiol modulate mitogen-induced tryptophan degradation and neopterin formation in peripheral blood mononuclear cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Cannabidiol-induced intracellular Ca2+ elevations in hippocampal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Interactions of cannabidiol with endocannabinoid signalling in hippocampal tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Time-dependent vascular actions of cannabidiol in the rat aorta

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Neuroprotective effects of phytocannabinoid-based medicines in experimental models of Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease: importance of antioxidant and cannabinoid receptor-independent properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Critical role of angiotensin II in excess salt-induced brain oxidative stress of stroke-prone spontaneously hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Cannabidiol inhibits the hyperphagia induced by cannabinoid-1 or serotonin-1A receptor agonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Anxiolytic-like effect of cannabinoids injected into the rat dorsolateral periaqueductal gray.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

The endogenous cannabinoid system controls extinction of aversive memories

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Effects of glutamate-related drugs on marble-burying behavior in mice: implications for obsessive-compulsive disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Effects of agents targeting glutamatergic systems on marble-burying behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

An open-label trial of riluzole, a glutamate antagonist, in children with treatment-resistant obsessive-compulsive disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Downregulation of the CB1 cannabinoid receptor and related molecular elements of the endocannabinoid system in epileptic human hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

TRPV1 receptor mediates glutamatergic synaptic input to dorsolateral periaqueductal gray (dl-PAG) neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Evidence for a potential role for TRPV1 receptors in the dorsolateral periaqueductal gray in the attenuation of the anxiolytic effects of cannabinoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Role in anxiety behavior of the endocannabinoid system in the prefrontal cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Cannabis-associated psychosis with hypomanic features

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Cannabidiol inhibits the hyperlocomotion induced by psychotomimetic drugs in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Effects of phencyclidine (PCP) and (+)MK-801 on sensorimotor gating in CD-1 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Effect of cannabidiol in a MK-801-rodent model of aspects of schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Different effects of nabilone and cannabidiol on binocular depth inversion in Man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

The interplay of cannabinoid and NMDA glutamate receptor systems in humans: preliminary evidence of interactive effects of cannabidiol and ketamine in healthy human subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Cannabidiol monotherapy for treatment-resistant schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

National Science and Technology Institute for Translational Medicine (INCT-TM): advancing the field of translational medicine and mental health.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Sub-chronic impact of cannabinoids in street cannabis on cognition, psychotic-like symptoms and psychological well-being.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Cannabis with high cannabidiol content is associated with fewer psychotic experiences.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Dorsolateral prefrontal cortex N-acetylaspartate/total creatine (NAA/tCr) loss in male recreational cannabis users.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Induction of psychosis by Δ9-tetrahydrocannabinol reflects modulation of prefrontal and striatal function during attentional salience processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Cannabidiol increases Fos expression in the nucleus accumbens but not in the dorsal striatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Effects on sleep and dopamine levels of microdialysis perfusion of cannabidiol into the lateral hypothalamus of rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Neural basis of Delta-9-tetrahydrocannabinol and cannabidiol: effects during response inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Modulation of mediotemporal and ventrostriatal function in humans by Delta9-tetrahydrocannabinol: a neural basis for the effects of Cannabis sativa on learning and psychosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Cannabidiol was ineffective for manic episode of bipolar affective disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal model of mania

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

Performance of schizophrenic patients in the Stroop Color Word Test and electrodermal responsiveness after acute administration of cannabidiol (CBD).

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481531

Cannabinoids inhibit the synaptic uptake of adenosine and dopamine in the rat and mouse striatum

28 November 2018

1 reference

12 December 2020

Pharmacological interaction between cannabidiol and delta 9-tetrahydrocannabinol

1 reference

12 December 2020

Cannabidiol and clozapine reverse MK-801-induced deficits in social interaction and hyperactivity in Sprague-Dawley rats

1 reference

12 December 2020

Is the highest density of CB1 receptors in paranoid schizophrenia a correlate of endocannabinoid system functioning?

1 reference

12 December 2020

Effects of ipsapirone and cannabidiol on human experimental anxiety

1 reference

12 December 2020

Interactions of delta 1-tetrahydrocannabinol with cannabinol and cannabidiol following oral administration in man. Assay of cannabinol and cannabidiol by mass fragmentography

1 reference

12 December 2020

Effects of cannabidiol in animal models predictive of antipsychotic activity

1 reference

12 December 2020

Cannabidiol increases Fos expression in the nucleus accumbens but not in the dorsal striatum

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

7 January 2021

inferred from DOI database lookup

Isolation, Structure, and Partial Synthesis of an Active Constituent of Hashish

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2011.0389

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1098/RSTB.2011.0389

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23108553%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23108553%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23108553%20AND%20SRC:MED&resulttype=core&format=json