Adiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes β-cell regeneration (Q34492575)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25339419%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

title

Adiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes β-cell regeneration (English)

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21 February 2020

1 reference

3

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21 February 2020

Mengle Shao

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21 February 2020

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Philipp E Scherer

1 reference

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21 February 2020

author name string

Risheng Ye

1

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21 February 2020

William L Holland

2

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21 February 2020

Miao Wang

4

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21 February 2020

Qiong A Wang

5

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21 February 2020

Thomas S Morley

7

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21 February 2020

Rana K Gupta

8

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21 February 2020

Andreas Stahl

9

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21 February 2020

language of work or name

English

0 references

publication date

23 October 2014

1 reference

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21 February 2020

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21 February 2020

volume

3

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describes a project that uses

21 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4228265/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Adiponectin, driver or passenger on the road to insulin sensitivity?

1 reference

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MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity.

6 July 2018

1 reference

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Adiponectin: mechanistic insights and clinical implications

6 July 2018

1 reference

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Altered mitochondrial function and metabolic inflexibility associated with loss of caveolin-1.

6 July 2018

1 reference

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Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover

6 July 2018

1 reference

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Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228265

Grp78 heterozygosity regulates chaperone balance in exocrine pancreas with differential response to cerulein-induced acute pancreatitis

6 July 2018

1 reference

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Regulation of beta-cell viability and gene expression by distinct agonist fragments of adiponectin

6 July 2018

1 reference

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Enhanced metabolic flexibility associated with elevated adiponectin levels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228265

Chronic palmitate exposure inhibits insulin secretion by dissociation of Ca(2+) channels from secretory granules

6 July 2018

1 reference

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Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistance

6 July 2018

1 reference

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Beta-cell deterioration during diabetes: what's in the gun?

6 July 2018

1 reference

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Endoplasmic reticulum stress in beta-cells and development of diabetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228265

Diabetes and apoptosis: lipotoxicity

6 July 2018

1 reference

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Adiponectin in health and disease: evaluation of adiponectin-targeted drug development strategies

6 July 2018

1 reference

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PANIC-ATTAC: a mouse model for inducible and reversible beta-cell ablation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228265

Adiponectin reduces plasma triglyceride by increasing VLDL triglyceride catabolism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228265

Plasma adiponectin complexes have distinct biochemical characteristics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228265

Glucolipotoxicity: fuel excess and beta-cell dysfunction.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228265

Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228265

Regulation of pancreatic beta-cell mass

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228265

Adiponectin counteracts cytokine- and fatty acid-induced apoptosis in the pancreatic beta-cell line INS-1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228265

A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228265

Diet-induced insulin resistance in mice lacking adiponectin/ACRP30

6 July 2018

1 reference

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Disruption of adiponectin causes insulin resistance and neointimal formation

6 July 2018

1 reference

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Molecular mechanisms regulating hormone-sensitive lipase and lipolysis

6 July 2018

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Lipoapoptosis in beta-cells of obese prediabetic fa/fa rats. Role of serine palmitoyltransferase overexpression

6 July 2018

1 reference

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Plasma lipid and lipoprotein disorders in IDDM

6 July 2018

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Palmitate inhibition of insulin gene expression is mediated at the transcriptional level via ceramide synthesis

6 July 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.03851

Metabolic mechanisms of failure of intraportally transplanted pancreatic beta-cells in rats: role of lipotoxicity and prevention by leptin.

21 January 2018

1 reference

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Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.03851

Distinct effects of saturated and monounsaturated fatty acids on beta-cell turnover and function

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.03851

Adiponectin increases insulin content and cell proliferation in MIN6 cells via PPARγ-dependent and PPARγ-independent mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.03851

Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalities

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.7554/ELIFE.03851

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25339419%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25339419%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference