Suppression of TNF-α and IL-1 signaling identifies a mechanism of homeostatic regulation of macrophages by IL-27 (Q34482169)

2 August 2017

Suppression of TNF-α and IL-1 signaling identifies a mechanism of homeostatic regulation of macrophages by IL-27 (English)

1 reference

2 August 2017

0 references

George D Kalliolias

1

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author name string

Rachael A Gordon

series ordinal

2

1 reference

PubMed ID

20971923

2 August 2017

Lionel B Ivashkiv

series ordinal

3

1 reference

PubMed ID

20971923

2 August 2017

language of work or name

English

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publication date

22 October 2010

1 reference

2 August 2017

Journal of Immunology

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2 August 2017

185

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2 August 2017

7047-7056

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2 August 2017

11

1 reference

The regulation of IL-10 production by immune cells

2 August 2017

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Th17 cytokines and arthritis

6 July 2018

1 reference

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Interleukin-27 inhibits human osteoclastogenesis by abrogating RANKL-mediated induction of nuclear factor of activated T cells c1 and suppressing proximal RANK signaling.

6 July 2018

1 reference

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Critical role of the IFN-stimulated gene factor 3 complex in TLR-mediated IL-27p28 gene expression revealing a two-step activation process

6 July 2018

1 reference

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Interleukin 27: a double-edged sword for offense and defense

6 July 2018

1 reference

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Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease

6 July 2018

1 reference

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Immunological and inflammatory functions of the interleukin-1 family

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019240

Regulation of immune responses by interleukin-27.

6 July 2018

1 reference

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Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin.

6 July 2018

1 reference

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Th17 cells in human disease.

6 July 2018

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Role of cytokines in rheumatoid arthritis: an education in pathophysiology and therapeutics

6 July 2018

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Primer: Toll-like receptor signaling pathways--what do rheumatologists need to know?

6 July 2018

1 reference

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The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice

6 July 2018

1 reference

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Advances in understanding the anti-inflammatory properties of IL-27.

6 July 2018

1 reference

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Cutting edge: A transcriptional repressor and corepressor induced by the STAT3-regulated anti-inflammatory signaling pathway

6 July 2018

1 reference

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Crosstalk among Jak-STAT, Toll-like receptor, and ITAM-dependent pathways in macrophage activation

6 July 2018

1 reference

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TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1.

6 July 2018

1 reference

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The biology and therapeutic potential of interleukin 27.

6 July 2018

1 reference

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Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation

6 July 2018

1 reference

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Regulation of IL-27 p28 gene expression in macrophages through MyD88- and interferon-gamma-mediated pathways

6 July 2018

1 reference

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Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells

6 July 2018

1 reference

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Interleukin-27R (WSX-1/T-cell cytokine receptor) gene-deficient mice display enhanced resistance to leishmania donovani infection but develop severe liver immunopathology

6 July 2018

1 reference

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The role of IL-27 in the development of T-cell responses during parasitic infections

6 July 2018

1 reference

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Understanding the pro- and anti-inflammatory properties of IL-27.

6 July 2018

1 reference

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WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019240

Expression of IL-27 in human Th1-associated granulomatous diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019240

IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1-dependent and -independent mechanisms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019240

Signalling pathways of the TNF superfamily: a double-edged sword

6 July 2018

1 reference

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Cutting Edge: Role of IL-27/WSX-1 Signaling for Induction of T-Bet Through Activation of STAT1 During Initial Th1 Commitment

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019240

IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells

6 July 2018

1 reference

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Interleukin-10 and the interleukin-10 receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019240

Development of Th1-type immune responses requires the type I cytokine receptor TCCR

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019240

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

6 July 2018

1 reference

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Possible roles of IL-27 in the pathogenesis of psoriasis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019240

IL-27 abrogates receptor activator of NF-kappa B ligand-mediated osteoclastogenesis of human granulocyte-macrophage colony-forming unit cells through STAT1-dependent inhibition of c-Fos.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019240

The mechanism of osteoclast differentiation induced by IL-1.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019240

Interleukin 27 attenuates collagen-induced arthritis.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019240

A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019240

Augmentation of antigen-presenting and Th1-promoting functions of dendritic cells by WSX-1(IL-27R) deficiency.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019240

IFN-alpha regulates Toll-like receptor-mediated IL-27 gene expression in human macrophages

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019240

Suppression of ongoing adjuvant-induced arthritis by neutralizing the function of the p28 subunit of IL-27.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019240

The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019240

Interleukin-10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019240

Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019240

RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-β

9 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019240

The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity

9 December 2018

1 reference

12 December 2020

Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells

1 reference

12 December 2020

IL-27 induces a Th1 immune response and susceptibility to experimental arthritis

1 reference

12 December 2020

IL-27 activates human monocytes via STAT1 and suppresses IL-10 production but the inflammatory functions of IL-27 are abrogated by TLRs and p38

1 reference

12 December 2020

The pathogenic role of interleukin-27 in autoimmune diabetes

1 reference

12 December 2020

The IL-27 receptor chain WSX-1 differentially regulates antibacterial immunity and survival during experimental tuberculosis

1 reference

12 December 2020

Exacerbation of experimental allergic asthma by augmented Th2 responses in WSX-1-deficient mice

1 reference

12 December 2020

Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system

1 reference

12 December 2020

IL-27 synthesis induced by TLR ligation critically depends on IFN regulatory factor 3

1 reference

12 December 2020

Suppressive effect of IL-27 on encephalitogenic Th17 cells and the effector phase of experimental autoimmune encephalomyelitis

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1001290

1 reference

release_imehoj6o5baprmvcf5f4aaxqfm

2 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/imehoj6o5baprmvcf5f4aaxqfm

24 November 2022

mapped directly with Wikidata item

PMCID

3019240

1 reference

2 August 2017

1 reference

PubMed ID

20971923