Timosaponin-BII inhibits the up-regulation of BACE1 induced by ferric chloride in rat retina (Q34452606)

2 August 2017

Timosaponin-BII inhibits the up-regulation of BACE1 induced by ferric chloride in rat retina (English)

1 reference

2 August 2017

Ju-Fang Huang

1

1 reference

2 August 2017

Lei Shang

2

1 reference

2 August 2017

Pei Liu

3

1 reference

2 August 2017

Meng-Qi Zhang

4

1 reference

2 August 2017

Shuang Chen

5

1 reference

2 August 2017

Dan Chen

6

1 reference

2 August 2017

Chun-Ling Fan

7

1 reference

2 August 2017

Hui Wang

8

1 reference

2 August 2017

Kun Xiong

9

1 reference

2 August 2017

22 October 2012

1 reference

BMC Complementary and Alternative Medicine

2 August 2017

1 reference

2 August 2017

12

1 reference

2 August 2017

189

1 reference

Creative Commons Attribution 2.0 Generic

2 August 2017

start time

22 October 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

exact match

https://scigraph.springernature.com/pub.10.1186/1472-6882-12-189

0 references

cites work

Methionine-35 of aβ(1-42): importance for oxidative stress in Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519506

Early induction of oxidative stress in mouse model of Alzheimer disease with reduced mitochondrial superoxide dismutase activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519506

Modes of Aβ toxicity in Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519506

Neurodegeneration of the retina in mouse models of Alzheimer's disease: what can we learn from the retina?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519506

Ocular biomarkers for early detection of Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519506

Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519506

Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519506

Proteomic identification of HNE-bound proteins in early Alzheimer disease: Insights into the role of lipid peroxidation in the progression of AD.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519506

Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519506

A new approach to the pharmacological regulation of memory: Sarsasapogenin improves memory by elevating the low muscarinic acetylcholine receptor density in brains of memory-deficit rat models

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519506

Multiple cognitive deficits during the transition to Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519506

Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519506

Alzheimer's disease: genes, proteins, and therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519506

Toward a comprehensive theory for Alzheimer's disease. Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid beta-protein.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519506

Clinical features of Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519506

Experimental traumatic brain injury in rats stimulates the expression, production and activity of Alzheimer's disease beta-secretase (BACE-1).

6 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1472-6882-12-189

Increased beta-secretase activity and expression in rats following transient cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1472-6882-12-189

Oxidative stress potentiates BACE1 gene expression and Abeta generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1472-6882-12-189

Energy inhibition elevates beta-secretase levels and activity and is potentially amyloidogenic in APP transgenic mice: possible early events in Alzheimer's disease pathogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1472-6882-12-189

beta-Secretase expression in normal and functionally deprived rat olfactory bulbs: inverse correlation with oxidative metabolic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1472-6882-12-189

Mitochondrial respiratory inhibition and oxidative stress elevate beta-secretase (BACE1) proteins and activity in vivo in the rat retina.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1472-6882-12-189

Oxidative stress induces intracellular accumulation of amyloid beta-protein (Abeta) in human neuroblastoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1472-6882-12-189

Oxidative stress increases expression and activity of BACE in NT2 neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1472-6882-12-189

Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1472-6882-12-189

Timosaponin B-II improves memory and learning dysfunction induced by cerebral ischemia in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1472-6882-12-189

Timosaponin B-II inhibits pro-inflammatory cytokine induction by lipopolysaccharide in BV2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1472-6882-12-189

A rapid and sensitive liquid chromatography-tandem mass spectrometric method for the determination of timosaponin B-II in blood plasma and a study of the pharmacokinetics of saponin in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1472-6882-12-189

Oxidative damage is the earliest event in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1472-6882-12-189

Effects of timosaponins on learning and memory abilities of rats with dementia induced by lateral cerebral ventricular injection of amyloid beta- peptide.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519506

Oxidative stress induces increase in intracellular amyloid beta-protein production and selective activation of betaI and betaII PKCs in NT2 cells

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519506

Capillary CAA and perivascular Aβ-deposition: two distinct features of Alzheimer's disease pathology

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23082924

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Antiplatelet and antithrombotic activities of timosaponin B-II, an extract of Anemarrhena asphodeloides

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23082924

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1472-6882-12-189

1 reference

Dimensions Publication ID

2 August 2017

0 references

1 reference

2 August 2017

1 reference