3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro (Q34452063)

2 August 2017

3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro (English)

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2 August 2017

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Alessi DR

1

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2 August 2017

Kozlowski MT

2

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2 August 2017

Weng QP

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2 August 2017

Morrice N

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2 August 2017

Avruch J

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2 August 2017

language of work or name

English

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publication date

1 January 1998

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2 August 2017

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2 August 2017

8

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2 August 2017

69-81

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2 August 2017

2

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p70 S6 kinase: an enigma with variations

2 August 2017

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https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970037-5

7 January 2021

Cloning and expression of two human p70 S6 kinase polypeptides differing only at their amino termini

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https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970037-5

7 January 2021

The Drosophila p70s6k homolog exhibits conserved regulatory elements and rapamycin sensitivity

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https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970037-5

7 January 2021

A Drosophila gene structurally and functionally homologous to the mammalian 70-kDa s6 kinase gene

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https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970037-5

7 January 2021

p70s6k function is essential for G1 progression

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https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970037-5

7 January 2021

Nuclear localization of p85s6k: functional requirement for entry into S phase.

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https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970037-5

7 January 2021

Insulin activates a 70-kDa S6 kinase through serine/threonine-specific phosphorylation of the enzyme polypeptide

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https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970037-5

7 January 2021

Molecular structure of a major insulin/mitogen-activated 70-kDa S6 protein kinase

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https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970037-5

7 January 2021

Activation of p70s6k is associated with phosphorylation of four clustered sites displaying Ser/Thr-Pro motifs

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970037-5

7 January 2021

Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970037-5

7 January 2021

Multiple independent inputs are required for activation of the p70 S6 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970037-5

7 January 2021

Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970037-5

7 January 2021

The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970037-5

7 January 2021

Dual requirement for a newly identified phosphorylation site in p70s6k

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https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970037-5

7 January 2021

The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970037-5

7 January 2021

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970037-5

7 January 2021

Mechanism of activation of protein kinase B by insulin and IGF-1

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970037-5

7 January 2021

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

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https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970037-5

7 January 2021

Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase

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https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970037-5

7 January 2021

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970037-5

7 January 2021

Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970037-5

7 January 2021

The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970037-5

7 January 2021

Comparison of the specificities of p70 S6 kinase and MAPKAP kinase-1 identifies a relatively specific substrate for p70 S6 kinase: the N-terminal kinase domain of MAPKAP kinase-1 is essential for peptide phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970037-5

7 January 2021

Identification of novel phosphorylation sites required for activation of MAPKAP kinase-2

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970037-5

7 January 2021

10.1016/S0960-9822(98)70037-5

Identifiers

DOI

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2 August 2017

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