The cytoplasmic peptide:N-glycanase (Ngly1)-basic science encounters a human genetic disorder (Q34448040)

2 August 2017

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title

The cytoplasmic peptide:N-glycanase (Ngly1)-basic science encounters a human genetic disorder (English)

1 reference

2 August 2017

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25398991%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

author name string

Tadashi Suzuki

series ordinal

1

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2 August 2017

13 November 2014

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2 August 2017

Journal of Biochemistry

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25398991%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

volume

157

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25398991%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25398991%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

page(s)

23-34

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25398991%20AND%20SRC:MED&resulttype=core&format=json

Biological roles of oligosaccharides: all of the theories are correct

8 June 2020

cites work

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Role of glycosylation in development

21 January 2018

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Demonstration of a new amidase acting on glycopeptides

21 January 2018

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Characterization of glycoproteins and their associated oligosaccharides through the use of endoglycosidases

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVU068

PNGases as valuable tools in glycoprotein analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Identification of peptide:N-glycanase activity in mammalian-derived cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Identification and distribution of peptide:N-glycanase (PNGase) in mouse organs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Occurrence and biological roles of 'proximal glycanases' in animal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

N-glycosylation/deglycosylation as a mechanism for the post-translational modification/remodification of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Protein degradation in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Degradation of CFTR by the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Proteasome-dependent endoplasmic reticulum-associated protein degradation: an unconventional route to a familiar fate

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVU068

The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVU068

ER quality control: the cytoplasmic connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Specificity and regulation of the endoplasmic reticulum-associated degradation machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Misfolded major histocompatibility complex class I heavy chains are translocated into the cytoplasm and degraded by the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Cytosolic degradation of T-cell receptor alpha chains by the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Aberrant retention of tyrosinase in the endoplasmic reticulum mediates accelerated degradation of the enzyme and contributes to the dedifferentiated phenotype of amelanotic melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Site-specific de-N-glycosylation of diglycosylated ovalbumin in hen oviduct by endogenous peptide: N-glycanase as a quality control system for newly synthesized proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

The class I antigen-processing pathway for the membrane protein tyrosinase involves translation in the endoplasmic reticulum and processing in the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

The mechanism underlying cystic fibrosis transmembrane conductance regulator transport from the endoplasmic reticulum to the proteasome includes Sec61beta and a cytosolic, deglycosylated intermediary

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Ubiquitination is required for the retro-translocation of a short-lived luminal endoplasmic reticulum glycoprotein to the cytosol for degradation by the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Aggresomes: a cellular response to misfolded proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Peptides glycosylated in the endoplasmic reticulum of yeast are subsequently deglycosylated by a soluble peptide: N-glycanase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

PNG1, a yeast gene encoding a highly conserved peptide:N-glycanase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Ngly1, a mouse gene encoding a deglycosylating enzyme implicated in proteasomal degradation: expression, genomic organization, and chromosomal mapping.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Cytoplasmic peptide:N-glycanase (PNGase) in eukaryotic cells: occurrence, primary structure, and potential functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Dual enzymatic properties of the cytoplasmic peptide: N-glycanase in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Unique peptide:N-glycanase of Caenorhabditis elegans has activity of protein disulphide reductase as well as of deglycosylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Identification of two discrete peptide: N-glycanases in Oryzias latipes during embryogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Identification and characterization of peptide: N-glycanase from Dictyostelium discoideum

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Molecular identification and characterization of peptide: N-glycanase from Schizosaccharomyces pombe

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

The Arabidopsis AtPNG1 gene encodes a peptide: N-glycanase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

The PUB domain: a putative protein-protein interaction domain implicated in the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Systematic identification of novel protein domain families associated with nuclear functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

The PUB domain functions as a p97 binding module in human peptide N-glycanase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

New ATPase regulators--p97 goes to the PUB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

NMR characterization of the interaction between the PUB domain of peptide:N-glycanase and ubiquitin-like domain of HR23

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Binding of OTULIN to the PUB domain of HOIP controls NF-κB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Structural and biochemical studies of the C-terminal domain of mouse peptide-N-glycanase identify it as a mannose-binding module

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Does an animal peptide: N-glycanase have the dual role as an enzyme and a carbohydrate-binding protein?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Carbohydrate-binding property of peptide: N-glycanase from mouse fibroblast L-929 cells as evaluated by inhibition and binding experiments using various oligosaccharides

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Site-specific labeling of cytoplasmic peptide:N-glycanase by N,N'-diacetylchitobiose-related compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Structural and mutational studies on the importance of oligosaccharide binding for the activity of yeast PNGase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Fluorescently labeled inhibitor for profiling cytoplasmic peptide:N-glycanase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Evidence for an essential deglycosylation-independent activity of PNGase in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

The Neurospora peptide:N-glycanase ortholog PNG1 is essential for cell polarity despite its lack of enzymatic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Using a small molecule inhibitor of peptide: N-glycanase to probe its role in glycoprotein turnover.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

z-VAD-fmk inhibits peptide:N-glycanase and may result in ER stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Rad23 provides a link between the Png1 deglycosylating enzyme and the 26 S proteasome in yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

The Saccharomyces cerevisiae DNA repair gene RAD23 encodes a nuclear protein containing a ubiquitin-like domain required for biological function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Rad23 links DNA repair to the ubiquitin/proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

The UBA2 domain functions as an intrinsic stabilization signal that protects Rad23 from proteasomal degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

The Png1-Rad23 complex regulates glycoprotein turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Structure of a peptide:N-glycanase-Rad23 complex: insight into the deglycosylation for denatured glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Structure of the mouse peptide N-glycanase-HR23 complex suggests co-evolution of the endoplasmic reticulum-associated degradation and DNA repair pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Peptide-N-glycanases and DNA repair proteins, Xp-C/Rad4, are, respectively, active and inactivated enzymes sharing a common transglutaminase fold

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Identification of proteins that interact with mammalian peptide:N-glycanase and implicate this hydrolase in the proteasome-dependent pathway for protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

A complex between peptide:N-glycanase and two proteasome-linked proteins suggests a mechanism for the degradation of misfolded glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

The retrotranslocation protein Derlin-1 binds peptide:N-glycanase to the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Multiple modes of interaction of the deglycosylation enzyme, mouse peptide N-glycanase, with the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

The AAA ATPase p97 links peptide N-glycanase to the endoplasmic reticulum-associated E3 ligase autocrine motility factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

E3 ubiquitin ligase that recognizes sugar chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Fbs1 protects the malfolded glycoproteins from the attack of peptide:N-glycanase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Hypothesis: a glycoprotein-degradation complex formed by protein-protein interaction involves cytoplasmic peptide:N-glycanase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Cytoplasmic peptide:N-glycanase and catabolic pathway for free N-glycans in the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Free-oligosaccharide control in the yeast Saccharomyces cerevisiae: roles for peptide:N-glycanase (Png1p) and vacuolar mannosidase (Ams1p)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Free oligosaccharides to monitor glycoprotein endoplasmic reticulum-associated degradation in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Endoplasmic reticulum-associated degradation (ERAD) and free oligosaccharide generation in Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Identification of roles for peptide: N-glycanase and endo-beta-N-acetylglucosaminidase (Engase1p) during protein N-glycosylation in human HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Eukaryotic oligosaccharyltransferase generates free oligosaccharides during N-glycosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Non-lysosomal degradation pathway for N-linked glycans and dolichol-linked oligosaccharides

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Endo-beta-N-acetylglucosaminidase, an enzyme involved in processing of free oligosaccharides in the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Identification of an endo-beta-N-acetylglucosaminidase gene in Caenorhabditis elegans and its expression in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Man2C1, an alpha-mannosidase, is involved in the trimming of free oligosaccharides in the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Free oligosaccharide regulation during mammalian protein N-glycosylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Identification of an Htm1 (EDEM)-dependent, Mns1-independent Endoplasmic Reticulum-associated Degradation (ERAD) pathway in Saccharomyces cerevisiae: application of a novel assay for glycoprotein ERAD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

A new autophagy-related checkpoint in the degradation of an ERAD-M target

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

An HLA-A2-restricted tyrosinase antigen on melanoma cells results from posttranslational modification and suggests a novel pathway for processing of membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Processing of a class I-restricted epitope from tyrosinase requires peptide N-glycanase and the cooperative action of endoplasmic reticulum aminopeptidase 1 and cytosolic proteases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

N-linked glycosylation does not impair proteasomal degradation but affects class I major histocompatibility complex presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

N-glycosylation enhances presentation of a MHC class I-restricted epitope from tyrosinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

An antigenic peptide produced by reverse splicing and double asparagine deamidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

A role for N-glycanase in the cytosolic turnover of glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

A glycosylated type I membrane protein becomes cytosolic when peptide: N-glycanase is compromised

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Deglycosylation-dependent fluorescent proteins provide unique tools for the study of ER-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

ERADication of EDEM1 occurs by selective autophagy and requires deglycosylation by cytoplasmic peptide N-glycanase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

The genetic basis of cellular morphogenesis in the filamentous fungus Neurospora crassa

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Characterization of the temperature-sensitive mutations un-7 and png-1 in Neurospora crassa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

The N-glycanase png-1 acts to limit axon branching during organ formation in Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Clinical application of exome sequencing in undiagnosed genetic conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Mutations in NGLY1 cause an inherited disorder of the endoplasmic reticulum-associated degradation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

A superfamily of archaeal, bacterial, and eukaryotic proteins homologous to animal transglutaminases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Site-directed mutagenesis study of yeast peptide:N-glycanase. Insight into the reaction mechanism of deglycosylation

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Clustal W and Clustal X version 2.0

21 January 2018

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Tools for integrated sequence-structure analysis with UCSF Chimera

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVU068

The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068

Endo-β-N-acetylglucosamidases (ENGases) in the fungus Trichoderma atroviride: possible involvement of the filamentous fungi-specific cytosolic ENGase in the ERAD process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU068