The polycomb group protein BMI1 is a transcriptional target of HDAC inhibitors. (Q34440758)

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5 February 2020

title

The polycomb group protein BMI1 is a transcriptional target of HDAC inhibitors (English)

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5 February 2020

1

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5 February 2020

author name string

Manjari Dimri

2

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5 February 2020

Anagh A Sahasrabuddhe

3

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5 February 2020

Janardan Khandekar

4

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5 February 2020

Goberdhan P Dimri

5

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5 February 2020

publication date

1 July 2010

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5 February 2020

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5 February 2020

volume

9

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5 February 2020

issue

13

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5 February 2020

page(s)

2663-2673

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Dietary omega-3 polyunsaturated fatty acids suppress expression of EZH2 in breast cancer cells.

5 February 2020

cites work

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CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells

6 July 2018

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Inhibition of histone deacetylases promotes ubiquitin-dependent proteasomal degradation of DNA methyltransferase 1 in human breast cancer cells

6 July 2018

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SWI/SNF mediates polycomb eviction and epigenetic reprogramming of the INK4b-ARF-INK4a locus

6 July 2018

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6 July 2018

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Bmi-1 cooperates with H-Ras to transform human mammary epithelial cells via dysregulation of multiple growth-regulatory pathways.

6 July 2018

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6 July 2018

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Histone deacetylases and cancer

6 July 2018

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c-Myc and Sp1 contribute to proviral latency by recruiting histone deacetylase 1 to the human immunodeficiency virus type 1 promoter

6 July 2018

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Modeling breast cancer-associated c-Src and EGFR overexpression in human MECs: c-Src and EGFR cooperatively promote aberrant three-dimensional acinar structure and invasive behavior

6 July 2018

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Polycomb comes of age: genome-wide profiling of target sites

6 July 2018

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Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells

6 July 2018

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Histone deacetylase inhibitors: signalling towards p21cip1/waf1.

6 July 2018

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The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

6 July 2018

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Elevated Bmi-1 expression is associated with dysplastic cell transformation during oral carcinogenesis and is required for cancer cell replication and survival

6 July 2018

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Polycomb silencing mechanisms and the management of genomic programmes

6 July 2018

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Histone deacetylase inhibitors deplete enhancer of zeste 2 and associated polycomb repressive complex 2 proteins in human acute leukemia cells

6 July 2018

1 reference

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Mel-18, a polycomb group protein, regulates cell proliferation and senescence via transcriptional repression of Bmi-1 and c-Myc oncoproteins

6 July 2018

1 reference

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Polycomb silencers control cell fate, development and cancer

6 July 2018

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Bmi-1 is a novel molecular marker of nasopharyngeal carcinoma progression and immortalizes primary human nasopharyngeal epithelial cells

6 July 2018

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The role of polycomb group proteins in cell cycle regulation during development

6 July 2018

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BMI1 is a target gene of E2F-1 and is strongly expressed in primary neuroblastomas

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010287

Histone deacetylase inhibitor, trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells

6 July 2018

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Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

6 July 2018

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Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing

6 July 2018

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Death-from-cancer signatures and stem cell contribution to metastatic cancer

6 July 2018

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Histone deacetylase inhibitors suppress the induction of c-Jun and its target genes including COX-2.

6 July 2018

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6 July 2018

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The primary mechanism of the IL-10-regulated antiinflammatory response is to selectively inhibit transcription

6 July 2018

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Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer

6 July 2018

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Histone deacetylase inhibitors down-regulate bcl-2 expression and induce apoptosis in t(14;18) lymphomas

6 July 2018

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The histone deacetylase inhibitor suberoylanilide hydroxamic acid down-regulates expression levels of Bcr-abl, c-Myc and HDAC3 in chronic myeloid leukemia cell lines.

6 July 2018

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Overexpression of Bmi-1 oncoprotein correlates with axillary lymph node metastases in invasive ductal breast cancer

6 July 2018

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SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex

6 July 2018

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Histone deacetylase inhibitors induce a senescence-like state in human cells by a p16-dependent mechanism that is independent of a mitotic clock

6 July 2018

1 reference

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Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1

6 July 2018

1 reference

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The Bmi-1 oncoprotein is overexpressed in human colorectal cancer and correlates with the reduced p16INK4a/p14ARF proteins

6 July 2018

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The histone deacetylase inhibitor MS-275 promotes differentiation or apoptosis in human leukemia cells through a process regulated by generation of reactive oxygen species and induction of p21CIP1/WAF1 1.

6 July 2018

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Role of histone H3 lysine 27 methylation in Polycomb-group silencing

6 July 2018

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The bmi-1 oncoprotein is differentially expressed in non-small cell lung cancer and correlates with INK4A-ARF locus expression

6 July 2018

1 reference

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Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation

6 July 2018

1 reference

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p57KIP2 expression and loss of heterozygosity during immortal conversion of cultured human mammary epithelial cells.

6 July 2018

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Regulation of apoptosis resistance and ontogeny of age-dependent diseases

6 July 2018

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Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent

6 July 2018

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo

6 July 2018

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BMI-1 is highly expressed in M0-subtype acute myeloid leukemia.

6 July 2018

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Histone deacetylase inhibitors: a new class of immunosuppressors targeting a novel signal pathway essential for CD154 expression

21 January 2018

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Histone deacetylase inhibition down-regulates cyclin D1 transcription by inhibiting nuclear factor-kappaB/p65 DNA binding

21 January 2018

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Activity of suberoylanilide hydroxamic Acid against human breast cancer cells with amplification of her-2.

21 January 2018

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HDAC inhibitors enhance the apoptosis-inducing potential of TRAIL in breast carcinoma

21 January 2018

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De-repression of the p21 promoter in prostate cancer cells by an isothiocyanate via inhibition of HDACs and c-Myc

21 January 2018

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A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20543557

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4161/CC.9.13.12147

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20543557%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20543557%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference