Mechanisms of polycomb gene silencing: knowns and unknowns (Q29614511)

Europe PubMed Central

title

Mechanisms of polycomb gene silencing: knowns and unknowns (English)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19738629

30 April 2017

0 references

Simon JA

1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19738629

30 April 2017

Kingston RE

series ordinal

2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19738629

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19738629

30 April 2017

language of work or name

1 reference

30 April 2017

publication date

October 2009

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19738629

Nature Reviews Molecular Cell Biology

30 April 2017

published in

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19738629

30 April 2017

volume

10

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19738629

30 April 2017

page(s)

697-708

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19738629

30 April 2017

issue

10

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19738629

Genomic biology: the epigenomic era opens

30 April 2017

cites work

1 reference

Gene regulation in the postgenomic era: technology takes the wheel

31 March 2020

1 reference

Chromatin state maps: new technologies, new insights

31 March 2020

1 reference

The role of chromatin during transcription

31 March 2020

1 reference

A gene complex controlling segmentation in Drosophila

31 March 2020

1 reference

A gene product required for correct initiation of segmental determination in Drosophila

31 March 2020

1 reference

A group of genes controlling the spatial expression of the bithorax complex in Drosophila

31 March 2020

1 reference

Maternal expression of genes that regulate the bithorax complex of Drosophila melanogaster.

31 March 2020

1 reference

In vivo binding pattern of a trans-regulator of homoeotic genes in Drosophila melanogaster

31 March 2020

1 reference

The polyhomeotic gene of Drosophila encodes a chromatin protein that shares polytene chromosome-binding sites with Polycomb

31 March 2020

1 reference

Genome-wide analysis of Polycomb targets in Drosophila melanogaster

31 March 2020

1 reference

Chromosomal distribution of PcG proteins during Drosophila development

31 March 2020

1 reference

Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster

31 March 2020

1 reference

Dynamic regulation by polycomb group protein complexes controls pattern formation and the cell cycle in Drosophila.

31 March 2020

1 reference

Stability and dynamics of polycomb target sites in Drosophila development.

31 March 2020

1 reference

Functional anatomy of polycomb and trithorax chromatin landscapes in Drosophila embryos

31 March 2020

1 reference

Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27.

31 March 2020

1 reference

Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

31 March 2020

1 reference

Polycomb complexes repress developmental regulators in murine embryonic stem cells

31 March 2020

1 reference

Control of developmental regulators by Polycomb in human embryonic stem cells

31 March 2020

1 reference

Suz12 binds to silenced regions of the genome in a cell-type-specific manner

31 March 2020

1 reference

Concise review: roles of polycomb group proteins in development and disease: a stem cell perspective

31 March 2020

1 reference

Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming

31 March 2020

1 reference

Stem cell regulation by polycomb repressors: postponing commitment

31 March 2020

1 reference

Transcriptional and epigenetic regulations of embryonic stem cells

31 March 2020

1 reference

Polycomb silencers control cell fate, development and cancer

31 March 2020

1 reference

The cancer epigenome--components and functional correlates

31 March 2020

1 reference

The epigenomics of cancer

31 March 2020

1 reference

Roles of the EZH2 histone methyltransferase in cancer epigenetics

31 March 2020

1 reference

Polycomb group and trithorax group proteins in Arabidopsis

31 March 2020

1 reference

Polycomb silencing mechanisms and the management of genomic programmes

31 March 2020

1 reference

Polycomb Group proteins: an evolutionary perspective.

31 March 2020

1 reference

Xist function: bridging chromatin and stem cells

31 March 2020

1 reference

X chromosome dosage compensation: how mammals keep the balance

31 March 2020

1 reference

Partners in imprinting: noncoding RNA and polycomb group proteins.

31 March 2020

1 reference

A mechanistic view of genomic imprinting

31 March 2020

1 reference

Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins

31 March 2020

1 reference

Genome regulation by polycomb and trithorax proteins

31 March 2020

1 reference

Programming off and on states in chromatin: mechanisms of Polycomb and trithorax group complexes

31 March 2020

1 reference

Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation

31 March 2020

1 reference

Methylation of lysine 4 on histone H3: intricacy of writing and reading a single epigenetic mark

31 March 2020

1 reference

Polycomb response elements and targeting of Polycomb group proteins in Drosophila.

31 March 2020

1 reference

Polycomb/Trithorax response elements and epigenetic memory of cell identity

31 March 2020

1 reference

The Drosophila Polycomb group gene pleiohomeotic encodes a DNA binding protein with homology to the transcription factor YY1.

31 March 2020

1 reference

A conserved sequence motif in Polycomb-response elements.

31 March 2020

1 reference

Functional analysis of repressor binding sites in the iab-2 regulatory region of the abdominal-A homeotic gene.

31 March 2020

1 reference

The Drosophila pho-like gene encodes a YY1-related DNA binding protein that is redundant with pleiohomeotic in homeotic gene silencing.

31 March 2020

1 reference

Hierarchical recruitment of polycomb group silencing complexes

31 March 2020

1 reference

A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities

31 March 2020

1 reference

Recruitment of Drosophila Polycomb group proteins to chromatin by DSP1.

31 March 2020

1 reference

Genome-wide prediction of Polycomb/Trithorax response elements in Drosophila melanogaster

31 March 2020

1 reference

Replacement of a Drosophila Polycomb response element core, and in situ analysis of its DNA motifs

31 March 2020

1 reference

A genomic code for nucleosome positioning

31 March 2020

1 reference

Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains

31 March 2020

1 reference

Unlocking the mechanisms of transcription factor YY1: are chromatin modifying enzymes the key?

31 March 2020

1 reference

The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation

31 March 2020

1 reference

Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity

31 March 2020

1 reference

Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs

31 March 2020

1 reference

Chromosomal silencing and localization are mediated by different domains of Xist RNA.

31 March 2020

1 reference

Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome

31 March 2020

1 reference

Kcnq1ot1 antisense noncoding RNA mediates lineage-specific transcriptional silencing through chromatin-level regulation

31 March 2020

1 reference

Polycomb group proteins Ezh2 and Rnf2 direct genomic contraction and imprinted repression in early mouse embryos

31 March 2020

1 reference

RNAi components are required for nuclear clustering of Polycomb group response elements.

31 March 2020

1 reference

Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells

31 March 2020

1 reference

The nuclear organization of Polycomb/Trithorax group response elements in larval tissues of Drosophila melanogaster

31 March 2020

1 reference

Non-coding RNAs in polycomb/trithorax regulation.

31 March 2020

1 reference

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

31 March 2020

1 reference

Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein

31 March 2020

1 reference

Histone methyltransferase activity of a Drosophila Polycomb group repressor complex

31 March 2020

1 reference

Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites

31 March 2020

1 reference

Partitioning and plasticity of repressive histone methylation states in mammalian chromatin

31 March 2020

1 reference

Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila

31 March 2020

1 reference

Subunit contributions to histone methyltransferase activities of fly and worm polycomb group complexes

31 March 2020

1 reference

Nucleosome binding and histone methyltransferase activity of Drosophila PRC2.

31 March 2020

1 reference

SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex

31 March 2020

1 reference

Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity

31 March 2020

1 reference

The N terminus of Drosophila ESC binds directly to histone H3 and is required for E(Z)-dependent trimethylation of H3 lysine 27.

31 March 2020

1 reference

Structural basis of histone H4 recognition by p55

31 March 2020

1 reference

Dominant alleles identify SET domain residues required for histone methyltransferase of Polycomb repressive complex 2.

31 March 2020

1 reference

Structural basis of EZH2 recognition by EED

31 March 2020

1 reference

Different EZH2-containing complexes target methylation of histone H1 or nucleosomal histone H3

31 March 2020

1 reference

Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation

31 March 2020

1 reference

Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins

31 March 2020

1 reference

EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

31 March 2020

1 reference

Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms

31 March 2020

1 reference

EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency

31 March 2020

1 reference

Alternative ESC and ESC-like subunits of a polycomb group histone methyltransferase complex are differentially deployed during Drosophila development

31 March 2020

1 reference

Drosophila ESC-like can substitute for ESC and becomes required for Polycomb silencing if ESC is absent

31 March 2020

1 reference

ESC, ESCL and their roles in Polycomb Group mechanisms.

31 March 2020

1 reference

Ezh2 requires PHF1 to efficiently catalyze H3 lysine 27 trimethylation in vivo.

31 March 2020

1 reference

Recruitment of Drosophila Polycomb-group proteins by Polycomblike, a component of a novel protein complex in larvae.

31 March 2020

1 reference

Pcl-PRC2 is needed to generate high levels of H3-K27 trimethylation at Polycomb target genes

31 March 2020

1 reference

Role of hPHF1 in H3K27 methylation and Hox gene silencing

31 March 2020

1 reference

Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains

31 March 2020

1 reference

Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27

31 March 2020

1 reference

Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing

31 March 2020

1 reference

Architecture of a polycomb nucleoprotein complex.

31 March 2020

1 reference

Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing

31 March 2020

1 reference

The polycomb group protein Suz12 is required for embryonic stem cell differentiation

31 March 2020

1 reference

Different polycomb group CBX family proteins associate with distinct regions of chromatin using nonhomologous protein sequences

31 March 2020

1 reference

Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination

31 March 2020

1 reference

Epigenetic transcriptional repression of cellular genes by a viral SET protein

31 March 2020

1 reference

Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2

31 March 2020

1 reference

Polycomb complexes and epigenetic states

31 March 2020

1 reference

MIG-32 and SPAT-3A are PRC1 homologs that control neuronal migration in Caenorhabditis elegans

31 March 2020

1 reference

Mechanisms of transcriptional memory

31 March 2020

1 reference

Division of labor in polycomb group repression

31 March 2020

1 reference

Biochemical mechanisms of gene regulation by polycomb group protein complexes

31 March 2020

1 reference

Stabilization of chromatin structure by PRC1, a Polycomb complex

31 March 2020

1 reference

Reconstitution of a functional core polycomb repressive complex.

31 March 2020

1 reference

Synergistic recognition of an epigenetic DNA element by Pleiohomeotic and a Polycomb core complex

31 March 2020

1 reference

The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans

31 March 2020

1 reference

Propagation of silencing; recruitment and repression of naive chromatin in trans by polycomb repressed chromatin.

31 March 2020

1 reference

Chromatin compaction by a polycomb group protein complex

31 March 2020

1 reference

Analysis of a polycomb group protein defines regions that link repressive activity on nucleosomal templates to in vivo function

31 March 2020

1 reference

Role of histone H2A ubiquitination in Polycomb silencing

31 March 2020

1 reference

Structure of a Bmi-1-Ring1B polycomb group ubiquitin ligase complex

31 March 2020

1 reference

Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b

31 March 2020

1 reference

Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells

31 March 2020

1 reference

dKDM2 couples histone H2A ubiquitylation to histone H3 demethylation during Polycomb group silencing

31 March 2020

1 reference

Polycomb group and SCF ubiquitin ligases are found in a novel BCOR complex that is recruited to BCL6 targets

31 March 2020

1 reference

Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor

31 March 2020

1 reference

Cooperation between EZH2, NSPc1-mediated histone H2A ubiquitination and Dnmt1 in HOX gene silencing

31 March 2020

1 reference

The MES-2/MES-3/MES-6 complex and regulation of histone H3 methylation in C. elegans.

31 March 2020

1 reference

Regulation of the different chromatin states of autosomes and X chromosomes in the germ line of C. elegans

31 March 2020

1 reference

Polycomb group regulation of Hox gene expression in C. elegans.

31 March 2020

1 reference

General transcription factors bind promoters repressed by Polycomb group proteins.

31 March 2020

1 reference

Polycomb silencing blocks transcription initiation.

31 March 2020

1 reference

Histone trimethylation and the maintenance of transcriptional ON and OFF states by trxG and PcG proteins

31 March 2020

1 reference

A Drosophila Polycomb group complex includes Zeste and dTAFII proteins.

31 March 2020

1 reference

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

31 March 2020

1 reference

Regulation of Hox gene activity by transcriptional elongation in Drosophila

31 March 2020

1 reference

Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters

31 March 2020

1 reference

Divergent transcription from active promoters

31 March 2020

1 reference

The Drosophila trithorax group protein Kismet facilitates an early step in transcriptional elongation by RNA Polymerase II.

31 March 2020

1 reference

Drosophila Kismet regulates histone H3 lysine 27 methylation and early elongation by RNA polymerase II

31 March 2020

1 reference

Transcription of bxd noncoding RNAs promoted by trithorax represses Ubx in cis by transcriptional interference

31 March 2020

1 reference

Modulation of heat shock gene expression by the TAC1 chromatin-modifying complex.

31 March 2020

1 reference

Histone H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongation

31 March 2020

1 reference

The chromatin-specific transcription elongation factor FACT comprises human SPT16 and SSRP1 proteins

31 March 2020

1 reference

Tracking FACT and the RNA polymerase II elongation complex through chromatin in vivo

31 March 2020

1 reference

Nucleosomes inhibit the initiation of transcription but allow chain elongation with the displacement of histones

31 March 2020

1 reference

Nucleosomes can form a polar barrier to transcript elongation by RNA polymerase II

31 March 2020

1 reference

A model for transmission of the H3K27me3 epigenetic mark

31 March 2020

1 reference

Polycomb proteins remain bound to chromatin and DNA during DNA replication in vitro

31 March 2020

1 reference

Probing long-distance regulatory interactions in the Drosophila melanogaster bithorax complex using Dam identification.

31 March 2020

1 reference

Polycomb response elements mediate the formation of chromosome higher-order structures in the bithorax complex.

31 March 2020

1 reference

A novel 6C assay uncovers Polycomb-mediated higher order chromatin conformations

31 March 2020

1 reference

PcG proteins, DNA methylation, and gene repression by chromatin looping.

31 March 2020

1 reference

Facultative heterochromatin: is there a distinctive molecular signature?

31 March 2020

1 reference

The emerging field of dynamic lysine methylation of non-histone proteins.

31 March 2020

1 reference

A polycomb repression signature in metastatic prostate cancer predicts cancer outcome

31 March 2020

1 reference

An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors

31 March 2020

1 reference

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

31 March 2020

1 reference

Epigenetics in human disease and prospects for epigenetic therapy

31 March 2020

1 reference

Epigenetic therapy of cancer: past, present and future

31 March 2020

1 reference

Dosage-dependent modifiers of polycomb and antennapedia mutations in Drosophila

31 March 2020

1 reference

ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation

31 March 2020

1 reference

MLL targets SET domain methyltransferase activity to Hox gene promoters

31 March 2020

1 reference

Trithorax and dCBP acting in a complex to maintain expression of a homeotic gene.

31 March 2020

1 reference

brahma: a regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2

31 March 2020

1 reference

Drosophila UTX is a histone H3 Lys27 demethylase that colocalizes with the elongating form of RNA polymerase II.

31 March 2020

1 reference

Pygopus activates Wingless target gene transcription through the mediator complex subunits Med12 and Med13.

31 March 2020

1 reference

The Drosophila BRM complex facilitates global transcription by RNA polymerase II

31 March 2020

1 reference

The histone methyltransferases Trithorax and Ash1 prevent transcriptional silencing by Polycomb group proteins

31 March 2020

1 reference

Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus

31 March 2020

1 reference

Comparison of germline mosaics of genes in the Polycomb group of Drosophila melanogaster

31 March 2020

1 reference

12 December 2020

The DNA-binding polycomb group protein pleiohomeotic mediates silencing of a Drosophila homeotic gene.

1 reference

12 December 2020

Identification of grandchildless loci whose products are required for normal germ-line development in the nematode Caenorhabditis elegans

1 reference

12 December 2020

The Drosophila kismet gene is related to chromatin-remodeling factors and is required for both segmentation and segment identity.

1 reference

12 December 2020

The Drosophila trithorax protein is a coactivator required to prevent re-establishment of polycomb silencing.

1 reference

12 December 2020

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19738629

Identifiers

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

577749

1004980736

0 references

577749

1 reference

Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19738629

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017