PTEN/Akt signaling controls mitochondrial respiratory capacity through 4E-BP1. (Q34438439)

2 August 2017

PTEN/Akt signaling controls mitochondrial respiratory capacity through 4E-BP1. (English)

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2 August 2017

Chong Kiat Goo

1

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2 August 2017

Hwee Ying Lim

2

1 reference

2 August 2017

Qin Shi Ho

3

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2 August 2017

Heng-Phon Too

4

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2 August 2017

Marie-Veronique Clement

5

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2 August 2017

Kim Ping Wong

6

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2 August 2017

language of work or name

English

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publication date

26 September 2012

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2 August 2017

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2 August 2017

7

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2 August 2017

e45806

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2 August 2017

9

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Creative Commons Attribution 4.0 International

2 August 2017

start time

26 September 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis

6 July 2018

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Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice

6 July 2018

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Portrait of PTEN: messages from mutant mice.

6 July 2018

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4E-binding protein 1: a key molecular "funnel factor" in human cancer with clinical implications

6 July 2018

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AKT/PKB signaling: navigating downstream

6 July 2018

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6 July 2018

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PTEN, more than the AKT pathway

6 July 2018

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Mitochondrial respiration defects in cancer cells cause activation of Akt survival pathway through a redox-mediated mechanism

6 July 2018

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

6 July 2018

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A mechanism of sulfite neurotoxicity: direct inhibition of glutamate dehydrogenase

6 July 2018

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Akt stimulates aerobic glycolysis in cancer cells

6 July 2018

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Extensive association of functionally and cytotopically related mRNAs with Puf family RNA-binding proteins in yeast

6 July 2018

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Transcriptional regulatory circuits controlling mitochondrial biogenesis and function

6 July 2018

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Rapid accumulation of Akt in mitochondria following phosphatidylinositol 3-kinase activation

6 July 2018

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In vivo and in organello assessment of OXPHOS activities

6 July 2018

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A PUF family portrait: 3'UTR regulation as a way of life

6 July 2018

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Isolation and subfractionation of mitochondria from animal cells and tissue culture lines

6 July 2018

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The Puf3 protein is a transcript-specific regulator of mRNA degradation in yeast

6 July 2018

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Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458951

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458951

4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458951

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458951

Assessment of mitochondrial oxidative phosphorylation in patient muscle biopsies, lymphoblasts, and transmitochondrial cell lines

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458951

Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458951

An evaluation of the measurement of the activities of complexes I-IV in the respiratory chain of human skeletal muscle mitochondria.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458951

Measurement of protein using bicinchoninic acid

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458951

Identification of tyrosine-phosphorylated proteins of the mitochondrial oxidative phosphorylation machinery

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458951

High-resolution respirometry: OXPHOS protocols for human cells and permeabilized fibers from small biopsies of human muscle

27 October 2018

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12 December 2020

Low mitochondrial proton leak due to high membrane cholesterol content and cytosolic creatine kinase as two features of the deviant bioenergetics of Ehrlich and AS30-D tumor cells

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12 December 2020

Activation of glycogen synthase kinase 3beta disrupts the binding of hexokinase II to mitochondria by phosphorylating voltage-dependent anion channel and potentiates chemotherapy-induced cytotoxicity

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12 December 2020

Action of diclofenac on kidney mitochondria and cells

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12 December 2020

Supercomplexes and subcomplexes of mitochondrial oxidative phosphorylation

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12 December 2020

Respiratory competent mitochondria in human ovarian and peritoneal cancer

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12 December 2020

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12 December 2020

10.1371/JOURNAL.PONE.0045806

Identifiers

DOI

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2 August 2017

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2 August 2017

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