IL-17 in severe asthma. Where do we stand? (Q34435370)

2 August 2017

IL-17 in severe asthma. Where do we stand? (English)

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2 August 2017

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Julie Chesné

1

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Faouzi Braza

object named as

Faouzi Braza

2

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author name string

Guillaume Mahay

3

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2 August 2017

Sophie Brouard

4

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2 August 2017

Marc Aronica

5

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2 August 2017

Antoine Magnan

6

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2 August 2017

language of work or name

English

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publication date

1 November 2014

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American Journal of Respiratory and Critical Care Medicine

2 August 2017

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2 August 2017

190

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2 August 2017

10

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2 August 2017

1094-1101

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Asthma phenotypes: the evolution from clinical to molecular approaches

2 August 2017

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Integrating longitudinal information on pulmonary function and inflammation using asthma phenotypes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Sputum gene expression signature of 6 biomarkers discriminates asthma inflammatory phenotypes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Unsupervised phenotyping of Severe Asthma Research Program participants using expanded lung data

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

T-helper type 2-driven inflammation defines major subphenotypes of asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Lebrikizumab treatment in adults with asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Mepolizumab and exacerbations of refractory eosinophilic asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Outcomes after cessation of mepolizumab therapy in severe eosinophilic asthma: a 12-month follow-up analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

The role of mepolizumab in atopic and nonatopic severe asthma with persistent eosinophilia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Mepolizumab for prednisone-dependent asthma with sputum eosinophilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

T(H)17-associated cytokines (IL-17A and IL-17F) in severe asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx?

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

IL-17-producing T cells in lung immunity and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Innate lymphoid cells and asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Type 2 innate lymphoid cells: new players in asthma and allergy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Innate lymphoid cells--how did we miss them?

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

IL-33-responsive lineage- CD25+ CD44(hi) lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Group 2 innate lymphoid cells are critical for the initiation of adaptive T helper 2 cell-mediated allergic lung inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

IL-17A and IL-17F Expression in B Lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Activation of neutrophils by autocrine IL-17A-IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORγt and dectin-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Resolution of allergic airway inflammation and airway hyperreactivity is mediated by IL-17-producing {gamma}{delta}T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Sputum neutrophil counts are associated with more severe asthma phenotypes using cluster analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Interleukin-17 in sputum correlates with airway hyperresponsiveness to methacholine

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Expression of the T helper 17-associated cytokines IL-17A and IL-17F in asthma and COPD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Th17 immunity in patients with allergic asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

A novel subset of CD4(+) T(H)2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Identification of a novel subset of human circulating memory CD4(+) T cells that produce both IL-17A and IL-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Increased IL-17A secreting CD4+ T cells, serum IL-17 levels and exhaled nitric oxide are correlated with childhood asthma severity

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Diesel exhaust particle induction of IL-17A contributes to severe asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Allergic sensitization through the airway primes Th17-dependent neutrophilia and airway hyperresponsiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Th17 responses in chronic allergic airway inflammation abrogate regulatory T-cell-mediated tolerance and contribute to airway remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

The neutrophilic inflammatory phenotype is associated with systemic inflammation in asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Critical regulation of early Th17 cell differentiation by interleukin-1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

The complex relationship between inflammation and lung function in severe asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Anti-interleukin-17A monoclonal antibody secukinumab in treatment of ankylosing spondylitis: a randomised, double-blind, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Interleukin-17 stimulates the expression of interleukin-8, growth-related oncogene-alpha, and granulocyte-colony-stimulating factor by human airway epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-alpha and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Invasive fungal infection and impaired neutrophil killing in human CARD9 deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Management of severe asthma in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Glucocorticoid receptor-beta up-regulation and steroid resistance induction by IL-17 and IL-23 cytokine stimulation in peripheral mononuclear cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Enhanced production of IL-17A in patients with severe asthma is inhibited by 1α,25-dihydroxyvitamin D3 in a glucocorticoid-independent fashion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Defective IL-10 expression and in vitro steroid-induced IL-17A in paediatric severe therapy-resistant asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Pro-inflammatory human Th17 cells selectively express P-glycoprotein and are refractory to glucocorticoids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Bronchial epithelial cells release IL-6, CXCL1 and CXCL8 upon mast cell interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Requirement for both JAK-mediated PI3K signaling and ACT1/TRAF6/TAK1-dependent NF-kappaB activation by IL-17A in enhancing cytokine expression in human airway epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Interleukin-17A induces glucocorticoid insensitivity in human bronchial epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Regulation and function of epithelial secreted phospholipase A2 group X in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Th17 cytokines induce pro-fibrotic cytokines release from human eosinophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Airway remodeling-associated mediators in moderate to severe asthma: effect of steroids on TGF-beta, IL-11, IL-17, and type I and type III collagen expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Co-culture of human bronchial fibroblasts and CD4+ T cells increases Th17 cytokine signature

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Regulation of airway MUC5AC expression by IL-1beta and IL-17A; the NF-kappaB paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Stimulation of airway mucin gene expression by interleukin (IL)-17 through IL-6 paracrine/autocrine loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Tissue remodelling in chronic bronchial diseases: from the epithelial to mesenchymal phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

IL-17 induces type V collagen overexpression and EMT via TGF-β-dependent pathways in obliterative bronchiolitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Importance of epithelial mesenchymal transition (EMT) in COPD and asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Th17-associated cytokines promote human airway smooth muscle cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Airway remodeling in asthma: new mechanisms and potential for pharmacological intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Autocrine-regulated airway smooth muscle cell migration is dependent on IL-17-induced growth-related oncogenes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

IL-17A produced by αβ T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Small G proteins in the cardiovascular system: physiological and pathological aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Randomized, double-blind, placebo-controlled study of brodalumab, a human anti-IL-17 receptor monoclonal antibody, in moderate to severe asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Effects of steroid therapy on inflammatory cell subtypes in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Evidence for a cross-talk between human neutrophils and Th17 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

Brodalumab, an Anti–Interleukin-17–Receptor Antibody for Psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201405-0859PP

10.1164/RCCM.201405-0859PP

21 January 2018

Identifiers

DOI

1 reference

2 August 2017

1 reference