Anti-interleukin-17A monoclonal antibody secukinumab in treatment of ankylosing spondylitis: a randomised, double-blind, placebo-controlled trial (Q46911236)

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scientific article published on 13 September 2013

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English	Anti-interleukin-17A monoclonal antibody secukinumab in treatment of ankylosing spondylitis: a randomised, double-blind, placebo-controlled trial	scientific article published on 13 September 2013

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scholarly article

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/24035250

Anti-interleukin-17A monoclonal antibody secukinumab in treatment of ankylosing spondylitis: a randomised, double-blind, placebo-controlled trial (English)

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Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/24035250

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ankylosing spondylitis

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monoclonal antibody

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http://europepmc.org/abstract/MED/24035250

Désirée van der Heijde

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Désirée van der Heijde

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Robert Landewé

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object named as

Robert Landewé

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Paul Emery

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Paul Wordsworth

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Paul Wordsworth

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http://europepmc.org/abstract/MED/24035250

author name string

Dominique Baeten

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http://europepmc.org/abstract/MED/24035250

Xenofon Baraliakos

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Jürgen Braun

3

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http://europepmc.org/abstract/MED/24035250

Joachim Sieper

4

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http://europepmc.org/abstract/MED/24035250

Jacob M van Laar

8

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http://europepmc.org/abstract/MED/24035250

Jürgen Wollenhaupt

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Herbert Kellner

12

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http://europepmc.org/abstract/MED/24035250

Jacqueline Paramarta

13

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http://europepmc.org/abstract/MED/24035250

Jiawei Wei

14

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http://europepmc.org/abstract/MED/24035250

Arndt Brachat

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http://europepmc.org/abstract/MED/24035250

Stephan Bek

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http://europepmc.org/abstract/MED/24035250

Didier Laurent

17

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http://europepmc.org/abstract/MED/24035250

Yali Li

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http://europepmc.org/abstract/MED/24035250

Ying A Wang

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http://europepmc.org/abstract/MED/24035250

Arthur P Bertolino

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Sandro Gsteiger

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Andrew M Wright

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http://europepmc.org/abstract/MED/24035250

Wolfgang Hueber

23

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language of work or name

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publication date

13 September 2013

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http://europepmc.org/abstract/MED/24035250

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http://europepmc.org/abstract/MED/24035250

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Spondyloarthritis

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Treatment of active ankylosing spondylitis with infliximab: a randomised controlled multicentre trial

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Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

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Inflammatory disease protective R381Q IL23 receptor polymorphism results in decreased primary CD4+ and CD8+ human T-cell functional responses

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7 January 2021

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HLA-B27 misfolding and the unfolded protein response augment interleukin-23 production and are associated with Th17 activation in transgenic rats

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Ankylosing spondylitis macrophage production of higher levels of interleukin-23 in response to lipopolysaccharide without induction of a significant unfolded protein response

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Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis

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Th17 cells expressing KIR3DL2+ and responsive to HLA-B27 homodimers are increased in ankylosing spondylitis

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Enrichment of circulating interleukin-17-secreting interleukin-23 receptor-positive γ/δ T cells in patients with active ankylosing spondylitis

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Analysis of IL-17(+) cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response

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7 January 2021

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Interleukin-17-positive mast cells contribute to synovial inflammation in spondylarthritis

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7 January 2021

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Proinflammatory Th17 cells are expanded and induced by dendritic cells in spondylarthritis-prone HLA-B27-transgenic rats

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7 January 2021

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IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4-CD8- entheseal resident T cells

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A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis

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Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis

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Brodalumab, an Anti–Interleukin-17–Receptor Antibody for Psoriasis

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Anti–Interleukin-17 Monoclonal Antibody Ixekizumab in Chronic Plaque Psoriasis

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Efficacy and safety of secukinumab in the treatment of moderate-to-severe plaque psoriasis: a randomized, double-blind, placebo-controlled phase II dose-ranging study

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Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria

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Ankylosing spondylitis assessment group preliminary definition of short-term improvement in ankylosing spondylitis

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Development of the ASQoL: a quality of life instrument specific to ankylosing spondylitis

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Treatment of ankylosing spondylitis in patients refractory to TNF-inhibition: are there alternatives?

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Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci

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Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

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Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial

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Adalimumab, etanercept and infliximab for the treatment of ankylosing spondylitis: a systematic review and economic evaluation

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Different response to rituximab in tumor necrosis factor blocker-naive patients with active ankylosing spondylitis and in patients in whom tumor necrosis factor blockers have failed: a twenty-four-week clinical trial

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Major reduction in spinal inflammation in patients with ankylosing spondylitis after treatment with infliximab: Results of a multicenter, randomized, double-blind, placebo-controlled magnetic resonance imaging study

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10.1016/S0140-6736(13)61134-4

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/24035250

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1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/24035250

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