Concomitant Notch activation and p53 deletion trigger epithelial-to-mesenchymal transition and metastasis in mouse gut. (Q34427267)

2 August 2017

Concomitant Notch activation and p53 deletion trigger epithelial-to-mesenchymal transition and metastasis in mouse gut. (English)

1 reference

2 August 2017

9

Ivan Bièche

0 references

Perrine Paul-Gilloteaux

8

Perrine Paul-Gilloteaux

0 references

Loredana Martignetti

Loredana Martignetti

15

0 references

Danijela Matic Vignjevic

Danijela Vignjevic

6

0 references

Emmanuel Barillot

Emmanuel Barillot

19

0 references

Daniel Louvard

20

Daniel Louvard

1 reference

2 August 2017

22

Sylvie Robine

1 reference

2 August 2017

4

Fatima El Marjou

1 reference

2 August 2017

Maia Chanrion

1

1 reference

2 August 2017

Inna Kuperstein

2

1 reference

2 August 2017

Cédric Barrière

3

1 reference

2 August 2017

David Cohen

5

1 reference

2 August 2017

Lev Stimmer

7

1 reference

2 August 2017

Silvina Dos Reis Tavares

10

1 reference

2 August 2017

Giuseppe-Fulvio Boccia

11

1 reference

2 August 2017

Wulfran Cacheux

12

1 reference

2 August 2017

Didier Meseure

13

1 reference

2 August 2017

Silvia Fre

14

1 reference

2 August 2017

Patricia Legoix-Né

16

1 reference

2 August 2017

Elodie Girard

17

1 reference

2 August 2017

Luc Fetler

18

1 reference

2 August 2017

Andreï Zinovyev

21

1 reference

2 August 2017

language of work or name

English

0 references

publication date

8 October 2014

1 reference

2 August 2017

Nature Communications

1 reference

2 August 2017

5

1 reference

2 August 2017

5005

1 reference

Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

2 August 2017

start time

8 October 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4214431/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/ncomms6005

0 references

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Presence of Twist1-positive neoplastic cells in the stroma of chromosome-unstable colorectal tumors

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EMT inducers catalyze malignant transformation of mammary epithelial cells and drive tumorigenesis towards claudin-low tumors in transgenic mice.

6 July 2018

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A novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transition

6 July 2018

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EMT and dissemination precede pancreatic tumor formation

6 July 2018

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Notch signal suppresses Toll-like receptor-triggered inflammatory responses in macrophages by inhibiting extracellular signal-regulated kinase 1/2-mediated nuclear factor κB activation

6 July 2018

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Axin pathway activity regulates in vivo pY654-β-catenin accumulation and pulmonary fibrosis

6 July 2018

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miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions

6 July 2018

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A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial-mesenchymal transition.

6 July 2018

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Tumor metastasis: molecular insights and evolving paradigms

6 July 2018

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An integrative genomic approach identifies p73 and p63 as activators of miR-200 microRNA family transcription

6 July 2018

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Notch post-translationally regulates β-catenin protein in stem and progenitor cells

6 July 2018

1 reference

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The ins and outs of the epithelial to mesenchymal transition in health and disease

6 July 2018

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Zeb1 is required for TrkB-induced epithelial-mesenchymal transition, anoikis resistance and metastasis

6 July 2018

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Activation of β-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters

6 July 2018

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Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling

6 July 2018

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Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells

6 July 2018

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Complex interplay between β-catenin signalling and Notch effectors in intestinal tumorigenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214431

Snail2 is an essential mediator of Twist1-induced epithelial mesenchymal transition and metastasis

6 July 2018

1 reference

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Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer

6 July 2018

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ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

6 July 2018

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Slug inhibits proliferation of human prostate cancer cells via downregulation of cyclin D1 expression

6 July 2018

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NF-kappaB promotes epithelial-mesenchymal transition, migration and invasion of pancreatic carcinoma cells

6 July 2018

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Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment

6 July 2018

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6 July 2018

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The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

6 July 2018

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Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility

6 July 2018

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6 July 2018

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The basics of epithelial-mesenchymal transition

6 July 2018

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Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine

6 July 2018

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TGF-beta receptor inactivation and mutant Kras induce intestinal neoplasms in mice via a beta-catenin-independent pathway

6 July 2018

1 reference

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Notch signaling mediates hypoxia-induced tumor cell migration and invasion

6 July 2018

1 reference

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Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin

6 July 2018

1 reference

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EMT tumorigenesis in the mouse mammary gland

6 July 2018

1 reference

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Fascin, a novel target of beta-catenin-TCF signaling, is expressed at the invasive front of human colon cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214431

Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

6 July 2018

1 reference

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APC and oncogenic KRAS are synergistic in enhancing Wnt signaling in intestinal tumor formation and progression

6 July 2018

1 reference

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A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer

6 July 2018

1 reference

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Towards a pan-European consensus on the treatment of patients with colorectal liver metastases

6 July 2018

1 reference

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Tumor metastasis: mechanistic insights and clinical challenges

6 July 2018

1 reference

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Complex networks orchestrate epithelial-mesenchymal transitions

6 July 2018

1 reference

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Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis

6 July 2018

1 reference

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Oncogenic pathway signatures in human cancers as a guide to targeted therapies

6 July 2018

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6 July 2018

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Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

6 July 2018

1 reference

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Snail blocks the cell cycle and confers resistance to cell death

6 July 2018

1 reference

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Notch signaling controls multiple steps of pancreatic differentiation

6 July 2018

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6 July 2018

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DNA microarrays identification of primary and secondary target genes regulated by p53.

6 July 2018

1 reference

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Tumorigenesis in the multiple intestinal neoplasia mouse: redundancy of negative regulators and specificity of modifiers

6 July 2018

1 reference

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Effects of p53 mutations on apoptosis in mouse intestinal and human colonic adenomas

6 July 2018

1 reference

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Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214431

Lessons from hereditary colorectal cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214431

A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214431

PTEN loss and KRAS activation leads to the formation of serrated adenomas and metastatic carcinoma in the mouse intestine.

6 July 2018

1 reference

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Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.

21 January 2018

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Tissue-specific and inducible Cre-mediated recombination in the gut epithelium

21 January 2018

1 reference

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The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6005

Integrative genomic analyses of ZEB2: Transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1alpha, POU/OCT, and NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6005

BiNoM: a Cytoscape plugin for manipulating and analyzing biological networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6005

Notch signals control the fate of immature progenitor cells in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6005

Crosstalk of Notch with p53 and p63 in cancer growth control

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25295490

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Using process diagrams for the graphical representation of biological networks

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25295490

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS6005

1 reference

Dimensions Publication ID

2 August 2017

0 references

0 references

1 reference

2 August 2017

1 reference