A selective histone deacetylase-6 inhibitor improves BDNF trafficking in hippocampal neurons from Mecp2 knockout mice: implications for Rett syndrome. (Q34410663)

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English	A selective histone deacetylase-6 inhibitor improves BDNF trafficking in hippocampal neurons from Mecp2 knockout mice: implications for Rett syndrome.	scientific article

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10 March 2020

A selective histone deacetylase-6 inhibitor improves BDNF trafficking in hippocampal neurons from Mecp2 knockout mice: implications for Rett syndrome (English)

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10 March 2020

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Lucas Pozzo-miller

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10 March 2020

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Xin Xu

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10 March 2020

Alan P Kozikowski

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7 March 2014

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10 March 2020

Frontiers in Cellular Neuroscience

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10 March 2020

Reduced axonal localization of a Caps2 splice variant impairs axonal release of BDNF and causes autistic-like behavior in mice.

1 reference

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6 July 2018

Activity-dependent BDNF release and TRPC signaling is impaired in hippocampal neurons of Mecp2 mutant mice

1 reference

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6 July 2018

HDAC6 inhibitor blocks amyloid beta-induced impairment of mitochondrial transport in hippocampal neurons

1 reference

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6 July 2018

Multiple approaches to investigate the transport and activity-dependent release of BDNF and their application in neurogenetic disorders

1 reference

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Loss of deacetylation activity of Hdac6 affects emotional behavior in mice

1 reference

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Modification of Mecp2 dosage alters axonal transport through the Huntingtin/Hap1 pathway

1 reference

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Positive feedback regulation between gamma-aminobutyric acid type A (GABA(A)) receptor signaling and brain-derived neurotrophic factor (BDNF) release in developing neurons

1 reference

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Rational design and simple chemistry yield a superior, neuroprotective HDAC6 inhibitor, tubastatin A

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Impaired TrkB-mediated ERK1/2 activation in huntington disease knock-in striatal cells involves reduced p52/p46 Shc expression

1 reference

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Modulation of dendritic spine development and plasticity by BDNF and vesicular trafficking: fundamental roles in neurodevelopmental disorders associated with mental retardation and autism

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Differential activity-dependent secretion of brain-derived neurotrophic factor from axon and dendrite

1 reference

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HDAC6 is a target for protection and regeneration following injury in the nervous system

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β-Amyloid impairs axonal BDNF retrograde trafficking

1 reference

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6 July 2018

Mechanisms, locations, and kinetics of synaptic BDNF secretion: an update.

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6 July 2018

The common BDNF polymorphism may be a modifier of disease severity in Rett syndrome

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6 July 2018

Therapeutic application of histone deacetylase inhibitors for central nervous system disorders

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6 July 2018

A bi-directional carboxypeptidase E-driven transport mechanism controls BDNF vesicle homeostasis in hippocampal neurons

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6 July 2018

MeCP2 deficiency in the brain decreases BDNF levels by REST/CoREST-mediated repression and increases TRKB production

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6 July 2018

The story of Rett syndrome: from clinic to neurobiology

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6 July 2018

Histone deacetylase 6 regulates growth factor-induced actin remodeling and endocytosis

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6 July 2018

Brain-derived neurotrophic factor expression and respiratory function improve after ampakine treatment in a mouse model of Rett syndrome.

1 reference

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6 July 2018

TRPC3 channels are necessary for brain-derived neurotrophic factor to activate a nonselective cationic current and to induce dendritic spine formation

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6 July 2018

Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation

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6 July 2018

Microtubule modification: acetylation speeds anterograde traffic flow

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6 July 2018

Microtubule acetylation promotes kinesin-1 binding and transport.

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Dysregulation of brain-derived neurotrophic factor expression and neurosecretory function in Mecp2 null mice

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6 July 2018

Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation

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6 July 2018

Molecular genetics of Rett syndrome: when DNA methylation goes unrecognized

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Rett syndrome: model of neurodevelopmental disorders

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6 July 2018

Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules

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DNA Methylation-Related Chromatin Remodeling in Activity-Dependent Bdnf Gene Regulation

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6 July 2018

Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2

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Neurotrophin secretion: current facts and future prospects

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6 July 2018

HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo

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The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function

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6 July 2018

In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation

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6 July 2018

HDAC6 is a microtubule-associated deacetylase

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6 July 2018

Synaptic secretion of BDNF after high-frequency stimulation of glutamatergic synapses

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Neurotrophins as synaptic modulators

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6 July 2018

Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice

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6 July 2018

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

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6 July 2018

BDNF-GFP containing secretory granules are localized in the vicinity of synaptic junctions of cultured cortical neurons.

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6 July 2018

MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

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6 July 2018

The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression.

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21 January 2018

GABA(B) receptor activation triggers BDNF release and promotes the maturation of GABAergic synapses.

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21 January 2018

Activity-dependent transfer of brain-derived neurotrophic factor to postsynaptic neurons.

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21 January 2018

Postsynaptic secretion of BDNF and NT-3 from hippocampal neurons depends on calcium calmodulin kinase II signaling and proceeds via delayed fusion pore opening.

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21 January 2018

Neurotrophic factors and Alzheimer's disease: are we focusing on the wrong molecule?

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27 October 2018

Mechanisms of the release of anterogradely transported neurotrophin-3 from axon terminals.

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27 October 2018

HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1–induced Charcot-Marie-Tooth disease

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21 January 2018

HDAC6 deacetylation of tubulin modulates dynamics of cellular adhesions

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12 December 2020

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10.3389/FNCEL.2014.00068

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10 March 2020

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Europe PubMed Central

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10 March 2020

1 reference

Europe PubMed Central

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10 March 2020

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