ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers (Q34383742)

1 August 2017

ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers (English)

1 reference

1 August 2017

Jill E Larsen

10

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Melanie H. Cobb

object named as

Melanie H Cobb

15

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Ignacio I Wistuba

13

object named as

Ignacio I Wistuba

1 reference

1 August 2017

Alexander Augustyn

1

1 reference

1 August 2017

Mark Borromeo

2

1 reference

1 August 2017

Tao Wang

3

1 reference

1 August 2017

Junya Fujimoto

4

1 reference

1 August 2017

Chunli Shao

5

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1 August 2017

Patrick D Dospoy

6

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1 August 2017

Victoria Lee

7

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1 August 2017

Christopher Tan

8

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1 August 2017

James P Sullivan

9

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1 August 2017

Luc Girard

11

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1 August 2017

Carmen Behrens

12

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1 August 2017

Yang Xie

14

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1 August 2017

Adi F Gazdar

16

1 reference

1 August 2017

Jane E Johnson

17

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1 August 2017

John D Minna

18

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1 August 2017

language of work or name

English

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publication date

29 September 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

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1 August 2017

111

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1 August 2017

41

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1 August 2017

14788-14793

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A transcription factor network specifying inhibitory versus excitatory neurons in the dorsal spinal cord

1 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

PTEN is a potent suppressor of small cell lung cancer.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

ASCL1 and RET expression defines a clinically relevant subgroup of lung adenocarcinoma characterized by neuroendocrine differentiation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

NeuroD1 regulates survival and migration of neuroendocrine lung carcinomas via signaling molecules TrkB and NCAM.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

Human lung epithelial cells progressed to malignancy through specific oncogenic manipulations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

Phase II study of single-agent navitoclax (ABT-263) and biomarker correlates in patients with relapsed small cell lung cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

Insights into the achaete-scute homolog-1 gene (hASH1) in normal and neoplastic human lung

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

Abnormalities of the TITF-1 lineage-specific oncogene in NSCLC: implications in lung cancer pathogenesis and prognosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

Small cell lung cancer: past, present, and future

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

GREAT improves functional interpretation of cis-regulatory regions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

Downregulation of drs tumor suppressor gene in highly malignant human pulmonary neuroendocrine tumors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

Achaete-scute complex homologue 1 regulates tumor-initiating capacity in human small cell lung cancer.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

Model-based analysis of ChIP-Seq (MACS)

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

Activity of the Bcl-2 family inhibitor ABT-263 in a panel of small cell lung cancer xenograft models

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

Therapeutic efficacy of ABT-737, a selective inhibitor of BCL-2, in small cell lung cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

Genomic profiling identifies TITF1 as a lineage-specific oncogene amplified in lung cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

Achaete-scute homolog-1 linked to remodeling and preneoplasia of pulmonary epithelium

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

DrugBank: a comprehensive resource for in silico drug discovery and exploration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

ASH1 gene is a specific therapeutic target for lung cancers with neuroendocrine features.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

Semi-supervised methods to predict patient survival from gene expression data

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

Two prognostically significant subtypes of high-grade lung neuroendocrine tumours independent of small-cell and large-cell neuroendocrine carcinomas identified by gene expression profiles.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

The new World Health Organization classification of lung tumours

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

Mash1 regulates neurogenesis in the ventral telencephalon

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

An achaete-scute homologue essential for neuroendocrine differentiation in the lung

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

Establishment and identification of small cell lung cancer cell lines having classic and variant features.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

Two rat homologues of Drosophila achaete-scute specifically expressed in neuronal precursors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205603

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1410419111

The diagnostic value of TTF-1, CK 5/6, and p63 immunostaining in classification of lung carcinomas

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25267614

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1410419111

1 reference

1 August 2017

0 references

1 reference

1 August 2017

1 reference