How specificity for self-peptides shapes the development and function of regulatory T cells (Q34378731)

1 August 2017

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title

How specificity for self-peptides shapes the development and function of regulatory T cells (English)

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1 August 2017

Donald M Simons

1

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1 August 2017

Cristina Cozzo Picca

2

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1 August 2017

Soyoung Oh

3

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1 August 2017

Olivia A Perng

4

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1 August 2017

Malinda Aitken

5

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1 August 2017

Jan Erikson

6

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1 August 2017

Andrew J Caton

7

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1 August 2017

publication date

21 May 2010

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Journal of Leukocyte Biology

1 August 2017

published in

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1 August 2017

volume

88

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1 August 2017

issue

6

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1 August 2017

page(s)

1099-1107

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CD4+CD25+ regulatory T cells in autoimmune arthritis

1 August 2017

cites work

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Th1, Th2, and Th17 effector T cell-induced autoimmune gastritis differs in pathological pattern and in susceptibility to suppression by regulatory T cells

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Physiologic self antigens rapidly capacitate autoimmune disease-specific polyclonal CD4+ CD25+ regulatory T cells

6 July 2018

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6 July 2018

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Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells.

6 July 2018

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CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes.

6 July 2018

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In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes

6 July 2018

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6 July 2018

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6 July 2018

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

6 July 2018

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Control of regulatory T cell development by the transcription factor Foxp3

6 July 2018

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Positive and negative selection of T cells

6 July 2018

1 reference

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Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in anti-myelin basic protein T cell receptor transgenic mice.

6 July 2018

1 reference

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Regulatory T cells: key controllers of immunologic self-tolerance

6 July 2018

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6 July 2018

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The third function of the thymus.

6 July 2018

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Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific

6 July 2018

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Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance

6 July 2018

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Peripheral autoantigen induces regulatory T cells that prevent autoimmunity

6 July 2018

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Regulatory CD4(+) T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis

6 July 2018

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CD4(+) T cells prevent spontaneous experimental autoimmune encephalomyelitis in anti-myelin basic protein T cell receptor transgenic mice

6 July 2018

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6 July 2018

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Evidence for a thymus-dependent form of tolerance that is not based on elimination or anergy of reactive T cells

6 July 2018

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Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation

6 July 2018

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Essential flexibility in the T-cell recognition of antigen

6 July 2018

1 reference

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Subversion of the immune system by pathogens.

6 July 2018

1 reference

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Negative selection of lymphocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996893

T cell receptor antagonist peptides induce positive selection

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996893

Specificity and flexibility in thymic selection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996893

Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptor

6 July 2018

1 reference

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Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996893

Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis

6 July 2018

1 reference

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Study on cellular events in postthymectomy autoimmune oophoritis in mice. I. Requirement of Lyt-1 effector cells for oocytes damage after adoptive transfer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996893

Evidence for a differential avidity model of T cell selection in the thymus

6 July 2018

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Crossref

https://api.crossref.org/works/10.1189%2FJLB.0310183

CD4+ CD25+ regulatory T cell repertoire formation in response to varying expression of a neo-self-antigen

21 January 2018

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Crossref

https://api.crossref.org/works/10.1189%2FJLB.0310183

Regulation of diabetes development by regulatory T cells in pancreatic islet antigen-specific TCR transgenic nonobese diabetic mice.

21 January 2018

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Crossref

https://api.crossref.org/works/10.1189%2FJLB.0310183

The impact of T helper and T regulatory cells on the regulation of anti-double-stranded DNA B cells

21 January 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996893

Anergy and suppression regulate CD4(+) T cell responses to a self peptide.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996893

Activation of CD4+ CD25+ regulatory T cell suppressor function by analogs of the selecting peptide

27 October 2018

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12 December 2020

CD4+ T cells recognizing a single self-peptide expressed by APCs induce spontaneous autoimmune arthritis

1 reference

12 December 2020

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

1 reference

12 December 2020

A T cell receptor transgenic model of severe, spontaneous organ-specific autoimmunity

1 reference

12 December 2020

Generation of CD4(+)CD25(+) regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression

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12 December 2020

Origin of regulatory T cells with known specificity for antigen

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12 December 2020

The thymus and negative selection

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12 December 2020

Identifiers

DOI

10.1189/JLB.0310183

1 reference

1 August 2017

1 reference

1 August 2017

1 reference