Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex (Q34375115)

1 August 2017

Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex (English)

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1 August 2017

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Jean-Yves Scoazec

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Nicolas Pallet

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Nicolas Pallet

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Udayan Apte

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object named as

Udayan Apte

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Ning Liang

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Chi Zhang

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Patricia Dill

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Ganna Panasyuk

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Delphine Pion

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Vonda Koka

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Morgan Gallazzini

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Eric N Olson

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Hilaire Lam

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Elizabeth P Henske

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Zheng Dong

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Randy L Johnson

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Fabiola Terzi

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David J Kwiatkowski

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Guido Martignoni

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Mario Pende

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language of work or name

English

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publication date

6 October 2014

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Journal of Experimental Medicine

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211

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2249-2263

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describes a project that uses

1 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4203941/fullTextXML

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inferred from PubMed Central ID database lookup

cites work

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Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts.

6 July 2018

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Efficacy and safety of everolimus for subependymal giant cell astrocytomas associated with tuberous sclerosis complex (EXIST-1): a multicentre, randomised, placebo-controlled phase 3 trial.

6 July 2018

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Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling

6 July 2018

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TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1

6 July 2018

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Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

6 July 2018

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The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells

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Regulation of insulin-like growth factor signaling by Yap governs cardiomyocyte proliferation and embryonic heart size

6 July 2018

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Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle

6 July 2018

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6 July 2018

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6 July 2018

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The hippo signaling pathway in development and cancer

6 July 2018

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Four-jointed modulates growth and planar polarity by reducing the affinity of dachsous for fat

6 July 2018

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A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)

6 July 2018

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6 July 2018

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An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1

6 July 2018

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TEAD mediates YAP-dependent gene induction and growth control

6 July 2018

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6 July 2018

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YAP1 increases organ size and expands undifferentiated progenitor cells

6 July 2018

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Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

6 July 2018

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6 July 2018

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A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival

6 July 2018

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The tuberous sclerosis complex

6 July 2018

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The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP

6 July 2018

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Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

6 July 2018

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Rheb fills a GAP between TSC and TOR.

6 July 2018

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Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFR

6 July 2018

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6 July 2018

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6 July 2018

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A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice

6 July 2018

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Tsc2(+/-) mice develop tumors in multiple sites that express gelsolin and are influenced by genetic background

6 July 2018

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Everolimus for angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis (EXIST-2): a multicentre, randomised, double-blind, placebo-controlled trial

6 July 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140341

Propranolol for severe hemangiomas of infancy.

21 January 2018

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https://api.crossref.org/works/10.1084%2FJEM.20140341

The Hippo pathway--from top to bottom and everything in between.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140341

Loss of Tsc1, but not Pten, in renal tubular cells causes polycystic kidney disease by activating mTORC1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140341

Transduction of mechanical and cytoskeletal cues by YAP and TAZ

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140341

21 January 2018

Identifiers

DOI

10.1084/JEM.20140341

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1 August 2017

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1 August 2017

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