Novel treatment of excitotoxicity: targeted disruption of intracellular signalling from glutamate receptors (Q28205804)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12963474%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

title

Novel treatment of excitotoxicity: targeted disruption of intracellular signalling from glutamate receptors (English)

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7 November 2019

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1

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7 November 2019

author name string

Michael Tymianski

series ordinal

2

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7 November 2019

language of work or name

English

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publication date

1 September 2003

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7 November 2019

published in

Biochemical Pharmacology

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12963474%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

volume

66

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12963474%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

page(s)

877-886

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7 November 2019

issue

6

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Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury?

7 November 2019

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7 January 2021

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7 January 2021

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7 January 2021

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Dual-component amino-acid-mediated synaptic potentials: excitatory drive for swimming in Xenopus embryos.

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Antagonism of non-NMDA receptors augments the neuroprotective effect of NMDA receptor blockade in cortical cultures subjected to prolonged deprivation of oxygen and glucose

7 January 2021

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Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons

7 January 2021

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Assessment of mitochondrial membrane potential as an indicator of cytotoxicity

7 January 2021

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Excitotoxic degeneration is initiated at non-random sites in cultured rat cerebellar neurons

7 January 2021

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Ionic dependence of glutamate neurotoxicity

7 January 2021

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7 January 2021

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Glutamate neurotoxicity in cortical cell culture is calcium dependent

7 January 2021

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Glutamate neurotoxicity, calcium, and zinc

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors.

7 January 2021

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The major tyrosine-phosphorylated protein in the postsynaptic density fraction is N-methyl-D-aspartate receptor subunit 2B

7 January 2021

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High-resolution immunogold localization of AMPA type glutamate receptor subunits at synaptic and non-synaptic sites in rat hippocampus

7 January 2021

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Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo

7 January 2021

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Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit

7 January 2021

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Regulatory phosphorylation of AMPA-type glutamate receptors by CaM-KII during long-term potentiation

7 January 2021

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Regulated subcellular distribution of the NR1 subunit of the NMDA receptor

7 January 2021

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Modulation of AMPA/kainate receptors in cultured murine hippocampal neurones by protein kinase C.

7 January 2021

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Regulation of signal transduction by protein targeting: the case for CaMKII.

7 January 2021

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NMDA channel regulation by channel-associated protein tyrosine kinase Src.

7 January 2021

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Competitive binding of alpha-actinin and calmodulin to the NMDA receptor

7 January 2021

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The AMPA receptor GluR2 C terminus can mediate a reversible, ATP-dependent interaction with NSF and alpha- and beta-SNAPs

7 January 2021

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Interaction of the N-ethylmaleimide-sensitive factor with AMPA receptors.

7 January 2021

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NSF binding to GluR2 regulates synaptic transmission

7 January 2021

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Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95

7 January 2021

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Clustering of AMPA receptors by the synaptic PDZ domain-containing protein PICK1

7 January 2021

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GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors

7 January 2021

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Novel anchorage of GluR2/3 to the postsynaptic density by the AMPA receptor-binding protein ABP

7 January 2021

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Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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NMDA-R1 subunit of the cerebral cortex co-localizes with neuronal nitric oxide synthase at pre- and postsynaptic sites and in spines.

7 January 2021

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Laminar organization of the NMDA receptor complex within the postsynaptic density.

7 January 2021

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SynGAP: a synaptic RasGAP that associates with the PSD-95/SAP90 protein family

7 January 2021

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Regulation of dendritic spine morphology by SPAR, a PSD-95-associated RapGAP

7 January 2021

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Citron binds to PSD-95 at glutamatergic synapses on inhibitory neurons in the hippocampus

7 January 2021

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Molecular organization of the postsynaptic specialization

7 January 2021

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PDZ domains: structural modules for protein complex assembly

7 January 2021

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Interaction of ion channels and receptors with PDZ domain proteins

7 January 2021

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Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and alpha1-syntrophin mediated by PDZ domains

7 January 2021

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Microtubule binding by CRIPT and its potential role in the synaptic clustering of PSD-95

7 January 2021

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CRIPT, a novel postsynaptic protein that binds to the third PDZ domain of PSD-95/SAP90

7 January 2021

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Interaction of the tyrosine kinase Pyk2 with the N-methyl-D-aspartate receptor complex via the Src homology 3 domains of PSD-95 and SAP102

7 January 2021

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Synapse structure: glutamate receptors connected by the shanks

7 January 2021

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Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin

7 January 2021

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PICK1: a perinuclear binding protein and substrate for protein kinase C isolated by the yeast two-hybrid system

7 January 2021

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PICK1 targets activated protein kinase Calpha to AMPA receptor clusters in spines of hippocampal neurons and reduces surface levels of the AMPA-type glutamate receptor subunit 2.

7 January 2021

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Identification of ion channel-associated proteins using the yeast two-hybrid system

7 January 2021

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AMPA receptor trafficking and synaptic plasticity

7 January 2021

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Mutagenesis reveals a role for ABP/GRIP binding to GluR2 in synaptic surface accumulation of the AMPA receptor

7 January 2021

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Reduction of GluR2 RNA editing, a molecular change that increases calcium influx through AMPA receptors, selective in the spinal ventral gray of patients with amyotrophic lateral sclerosis

7 January 2021

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The influence of glutamate receptor 2 expression on excitotoxicity in Glur2 null mutant mice.

7 January 2021

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GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex

7 January 2021

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Physiological and pathological caspase cleavage of the neuronal RasGEF GRASP-1 as detected using a cleavage site-specific antibody

7 January 2021

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Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell death

7 January 2021

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Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein

7 January 2021

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Role of actin in anchoring postsynaptic receptors in cultured hippocampal neurons: differential attachment of NMDA versus AMPA receptors.

7 January 2021

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Distinct roles of synaptic and extrasynaptic NMDA receptors in excitotoxicity

7 January 2021

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Nitric oxide signaling in the nervous system

7 January 2021

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Cloning and characterization of postsynaptic density 93, a nitric oxide synthase interacting protein.

7 January 2021

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PDZ domain of neuronal nitric oxide synthase recognizes novel C-terminal peptide sequences

7 January 2021

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AMPA receptor antagonists

7 January 2021

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Inhibitors of AMPA and kainate receptors

7 January 2021

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Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain.

7 January 2021

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Cellular uptake of the tat protein from human immunodeficiency virus

7 January 2021

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TAT-mediated protein transduction into mammalian cells

7 January 2021

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Plasma clearance, tissue distribution and catabolism of cationized albumins with increasing isoelectric points in the rat

7 January 2021

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Conjugation of poly-L-lysine to albumin and horseradish peroxidase: a novel method of enhancing the cellular uptake of proteins

7 January 2021

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Cell-penetrating peptides.

7 January 2021

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Messenger proteins: homeoproteins, TAT and others

7 January 2021

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Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent.

7 January 2021

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Intercellular trafficking and protein delivery by a herpesvirus structural protein

7 January 2021

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In vivo protein transduction: delivery of a biologically active protein into the mouse

7 January 2021

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Protein modules and signalling networks

7 January 2021

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Small molecule antagonists of proteins

7 January 2021

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10.1016/S0006-2952(03)00297-1

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12963474%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference