Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage (Q34353149)

1 August 2017

Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage (English)

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1 August 2017

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protein ubiquitination

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Jian Hu

1

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1 August 2017

Chad M McCall

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2

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1 August 2017

Tomohiko Ohta

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3

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1 August 2017

Yue Xiong

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4

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1 August 2017

26 September 2004

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1 August 2017

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1 August 2017

6

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1 August 2017

10

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1 August 2017

1003-1009

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https://scigraph.springernature.com/pub.10.1038/ncb1172

1 August 2017

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7 January 2021

SCF and Cullin/Ring H2-based ubiquitin ligases

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7 January 2021

The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases

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7 January 2021

Activation of UBC5 ubiquitin-conjugating enzyme by the RING finger of ROC1 and assembly of active ubiquitin ligases by all cullins

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7 January 2021

SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

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7 January 2021

F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex

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7 January 2021

A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p

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7 January 2021

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

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7 January 2021

The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families

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7 January 2021

The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

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7 January 2021

Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase

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7 January 2021

Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function

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7 January 2021

Targeting of protein ubiquitination by BTB–Cullin 3–Roc1 ubiquitin ligases

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7 January 2021

BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases

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7 January 2021

The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase.

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7 January 2021

BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3.

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7 January 2021

Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast

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7 January 2021

CUL-4 ubiquitin ligase maintains genome stability by restraining DNA-replication licensing

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7 January 2021

CUL-4A is critical for early embryonic development

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7 January 2021

TFDP1, CUL4A, and CDC16 identified as targets for amplification at 13q34 in hepatocellular carcinomas

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7 January 2021

Radiation-mediated proteolysis of CDT1 by CUL4–ROC1 and CSN complexes constitutes a new checkpoint

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7 January 2021

CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein

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7 January 2021

The p127 subunit (DDB1) of the UV-DNA damage repair binding protein is essential for the targeted degradation of STAT1 by the V protein of the paramyxovirus simian virus 5

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7 January 2021

Paramyxoviruses SV5 and HPIV2 assemble STAT protein ubiquitin ligase complexes from cellular components.

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7 January 2021

STAT3 ubiquitylation and degradation by mumps virus suppress cytokine and oncogene signaling

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7 January 2021

Human De-etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligase

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7 January 2021

Cullin 4A associates with the UV-damaged DNA-binding protein DDB

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7 January 2021

NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases

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7 January 2021

CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex

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7 January 2021

The SCF(Skp2) ubiquitin ligase complex interacts with the human replication licensing factor Cdt1 and regulates Cdt1 degradation

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7 January 2021

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

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7 January 2021

The xeroderma pigmentosum group E gene product DDB2 is a specific target of cullin 4A in mammalian cells

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7 January 2021

Xeroderma pigmentosum group E cells lack a nuclear factor that binds to damaged DNA

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7 January 2021

The V protein of the paramyxovirus SV5 interacts with damage-specific DNA binding protein

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7 January 2021

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

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7 January 2021

Identifiers

DOI

10.1038/NCB1172

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Dimensions Publication ID

1 August 2017

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