Induction of KLF4 in basal keratinocytes blocks the proliferation-differentiation switch and initiates squamous epithelial dysplasia (Q34338550)

1 August 2017

Induction of KLF4 in basal keratinocytes blocks the proliferation-differentiation switch and initiates squamous epithelial dysplasia (English)

1 reference

1 August 2017

1 reference

Iuri D Louro

8

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author name string

K Wade Foster

1

1 reference

1 August 2017

Zhaoli Liu

2

1 reference

1 August 2017

Clinton D Nail

3

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1 August 2017

Xingnan Li

4

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1 August 2017

Thomas J Fitzgerald

5

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1 August 2017

Sarah K Bailey

6

1 reference

1 August 2017

Andra R Frost

7

1 reference

1 August 2017

Tim M Townes

9

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1 August 2017

Andrew J Paterson

10

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1 August 2017

Jeffrey E Kudlow

11

1 reference

1 August 2017

Susan M Lobo-Ruppert

12

1 reference

1 August 2017

J Michael Ruppert

13

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1 August 2017

language of work or name

English

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publication date

1 February 2005

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1 August 2017

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1 August 2017

24

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1 August 2017

1491-1500

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1 August 2017

9

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1208307

1 August 2017

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Focus on head and neck cancer

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Identification of Krüppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer

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Progressive vascular changes in a transgenic mouse model of squamous cell carcinoma

6 July 2018

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Live and let die in the intestinal epithelium

6 July 2018

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Enterocyte differentiation marker intestinal alkaline phosphatase is a target gene of the gut-enriched Kruppel-like factor

6 July 2018

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Overexpression of Krüppel-like factor 4 in the human colon cancer cell line RKO leads to reduced tumorigenecity

6 July 2018

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Ectopic expression of Kruppel like factor 4 (Klf4) accelerates formation of the epidermal permeability barrier

6 July 2018

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Notch and cancer: best to avoid the ups and downs.

6 July 2018

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Krüppel-like factor 4 (KLF4/GKLF) is a target of bone morphogenetic proteins and transforming growth factor beta 1 in the regulation of vascular smooth muscle cell phenotype.

6 July 2018

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The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

6 July 2018

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Comparative gene expression profile analysis of GLI and c-MYC in an epithelial model of malignant transformation.

6 July 2018

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The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon.

6 July 2018

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Building 'validated' mouse models of human cancer

6 July 2018

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Mouse models for multistep tumorigenesis

6 July 2018

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The Hedgehog and Wnt signalling pathways in cancer

6 July 2018

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Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

6 July 2018

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Increase of GKLF messenger RNA and protein expression during progression of breast cancer

6 July 2018

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Positive- and negative-acting Kruppel-like transcription factors bind a transforming growth factor beta control element required for expression of the smooth muscle cell differentiation marker SM22alpha in vivo.

6 July 2018

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Gut-enriched Krüppel-like factor represses cyclin D1 promoter activity through Sp1 motif

6 July 2018

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The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361530

6 July 2018

The Hallmarks of Cancer

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Characterization of the structure and regulation of the murine gene encoding gut-enriched Krüppel-like factor (Krüppel-like factor 4).

6 July 2018

1 reference

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6 July 2018

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Klf4 is a transcription factor required for establishing the barrier function of the skin

6 July 2018

1 reference

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Oncogene expression cloning by retroviral transduction of adenovirus E1A-immortalized rat kidney RK3E cells: transformation of a host with epithelial features by c-MYC and the zinc finger protein GKLF.

6 July 2018

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Conditional expression of the ErbB2 oncogene elicits reversible hyperplasia in stratified epithelia and up-regulation of TGFalpha expression in transgenic mice

6 July 2018

1 reference

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Onset of keratin 17 expression coincides with the definition of major epithelial lineages during skin development

6 July 2018

1 reference

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The gut-enriched Krüppel-like factor suppresses the activity of the CYP1A1 promoter in an Sp1-dependent fashion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361530

Transactivation of the human keratin 4 and Epstein-Barr virus ED-L2 promoters by gut-enriched Krüppel-like factor

6 July 2018

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Expression of the gut-enriched Krüppel-like factor gene during development and intestinal tumorigenesis

6 July 2018

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Cytokeratin and vimentin expression in normal epithelium and squamous cell carcinomas of the larynx

6 July 2018

1 reference

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Cancer-susceptibility genes. Gatekeepers and caretakers

6 July 2018

1 reference

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Genetic predisposition and parameters of malignant progression in K14-HPV16 transgenic mice.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361530

Frequent clones of p53-mutated keratinocytes in normal human skin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361530

A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361530

Conditional gene expression in secretory tissues and skin of transgenic mice using the MMTV-LTR and the tetracycline responsive system

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361530

Identification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361530

Human homolog of patched, a candidate gene for the basal cell nevus syndrome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361530

Sending and receiving the hedgehog signal: control by the Drosophila Gli protein Cubitus interruptus.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361530

The incidence of p53 mutations increases with progression of head and neck cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361530

A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361530

Transgenic mice and squamous multistage skin carcinogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361530

Progressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361530

Clonal origin of chemically induced papillomas: separate analysis of epidermal and dermal components.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361530

Oncogenes, antioncogenes, and the molecular bases of multistep carcinogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361530

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361530

Comparison of epidermal patch size in X-chromosome-linked mosaic and dizygotic chimeric mice.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361530

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361530

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361530

[1] Isolation and utilization of epidermal keratinocytes for oncogene research

6 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208307

Signal transduction by transforming growth factor-β: A cooperative paradigm with extensive negative regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208307

Rapid Compensation for Glycosylphosphatidylinositol Anchor Deficient Keratinocytes after Birth: Visualization of Glycosylphosphatidylinositol-Anchored Proteins in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208307

Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208307

Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208307

Sunburn and p53 in the onset of skin cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208307

Squamous cell tumors in mice heterozygous for a null allele of Atp2a2, encoding the sarco(endo)plasmic reticulum Ca2+-ATPase isoform 2 Ca2+ pump

21 January 2018

1 reference

PubMed

12 December 2020

1 reference

12 December 2020

Development of mammary hyperplasia and neoplasia in MMTV-TGF alpha transgenic mice

1 reference

PubMed

12 December 2020

Signal transduction by transforming growth factor-beta: a cooperative paradigm with extensive negative regulation

1 reference

PubMed

12 December 2020

Identifiers

DOI

10.1038/SJ.ONC.1208307

1 reference

Dimensions Publication ID

1 August 2017

0 references

1 reference

1 August 2017

1 reference