BMP type I receptor inhibition reduces heterotopic [corrected] ossification (Q24611307)

12

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Mary L. Bouxsein

6

object named as

Mary L Bouxsein

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author name string

Donna Y Deng

2

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Carol S Lai

3

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Charles C Hong

4

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Gregory D Cuny

5

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Deborah W Hong

7

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Patrick M McManus

8

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Takenobu Katagiri

9

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Chetana Sachidanandan

10

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Nobuhiro Kamiya

11

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Yuji Mishina

13

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Randall T Peterson

14

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Kenneth D Bloch

A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva

15

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language of work or name

English

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publication date

December 2008

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published in

Nature Medicine

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volume

14

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issue

12

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page(s)

1363-9

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cites work

1 reference

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ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development

7 April 2017

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Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter

7 April 2017

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Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2

7 April 2017

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Cloning and characterization of a transmembrane serine kinase that acts as an activin type I receptor

7 April 2017

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Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

7 April 2017

1 reference

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Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism

7 April 2017

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Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse

7 April 2017

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Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

7 April 2017

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Constitutively activated ALK2 and increased SMAD1/5 cooperatively induce bone morphogenetic protein signaling in fibrodysplasia ossificans progressiva.

7 April 2017

1 reference

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Structure-activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors

27 September 2017

1 reference

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Insights from a rare genetic disorder of extra-skeletal bone formation, fibrodysplasia ossificans progressiva (FOP)

27 September 2017

1 reference

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Fibrodysplasia ossificans progressiva

27 September 2017

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Dysregulated BMP signaling and enhanced osteogenic differentiation of connective tissue progenitor cells from patients with fibrodysplasia ossificans progressiva (FOP).

27 September 2017

1 reference

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Endothelial Bmp4 is induced during arterial remodeling: effects on smooth muscle cell migration and proliferation

27 September 2017

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A new era for fibrodysplasia ossificans progressiva: a druggable target for the second skeleton

27 September 2017

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BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk

27 September 2017

1 reference

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Consequences of knocking out BMP signaling in the mouse

27 September 2017

1 reference

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Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblast and chondroblast differentiation.

27 September 2017

1 reference

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Identification of receptors and Smad proteins involved in activin signalling in a human epidermal keratinocyte cell line

27 September 2017

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Fibrodysplasia ossificans progressiva: still turning into wood after 300 years?

27 September 2017

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Bone morphogenetic protein (BMP) type II receptor is required for BMP-mediated growth arrest and differentiation in pulmonary artery smooth muscle cells

27 September 2017

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Crossref

https://api.crossref.org/works/10.1038%2FNM.1888

BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing.

21 January 2018

1 reference

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Generation of a mouse with conditionally activated signaling through the BMP receptor, ALK2.

28 November 2018

1 reference

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Biological effects of rAAV-caAlk2 coating on structural allograft healing.

28 November 2018

1 reference

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Bone morphogenetic protein (BMP) type II receptor deletion reveals BMP ligand-specific gain of signaling in pulmonary artery smooth muscle cells

28 November 2018

1 reference

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Factors associated with induced chronic inflammation in mdx skeletal muscle cause posttranslational stabilization and augmentation of extrasynaptic sarcolemmal utrophin

28 November 2018

1 reference

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Hematopoietic stem-cell contribution to ectopic skeletogenesis

28 November 2018

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12 December 2020

Functional modeling of the ACVR1 (R206H) mutation in FOP

1 reference

12 December 2020

Stromal cells of fibrodysplasia ossificans progressiva lesions express smooth muscle lineage markers and the osteogenic transcription factor Runx2/Cbfa-1: clues to a vascular origin of heterotopic ossification?

1 reference

12 December 2020

Influenza-like viral illnesses and flare-ups of fibrodysplasia ossificans progressiva

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12 December 2020

Surgical management of Paget's disease of bone

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Crossref

https://api.crossref.org/works/10.1038%2FNM.1888

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NM.1888

1 reference

Dimensions Publication ID

464118

1017877742

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Fatcat ID

release_7vpodgy5mnaprgb6gmbqshoqha

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/7vpodgy5mnaprgb6gmbqshoqha

24 November 2022

mapped directly with Wikidata item

464118

1 reference

1 reference

1 reference