Mkk4 is a negative regulator of the transforming growth factor beta 1 signaling associated with atrial remodeling and arrhythmogenesis with age. (Q34297226)

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English	Mkk4 is a negative regulator of the transforming growth factor beta 1 signaling associated with atrial remodeling and arrhythmogenesis with age.	scientific article

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scholarly article

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Europe PubMed Central

1 August 2017

Mkk4 is a negative regulator of the transforming growth factor beta 1 signaling associated with atrial remodeling and arrhythmogenesis with age. (English)

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Europe PubMed Central

1 August 2017

atrial remodeling

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James A. Fraser

11

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13 June 2020

Vincent M. Christoffels

13

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13 June 2020

Elizabeth J Cartwright

17

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13 June 2020

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13 June 2020

author name string

Laura Davies

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13 June 2020

Jiawei Jin

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13 June 2020

Weijin Shen

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13 June 2020

Hoyee Tsui

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13 June 2020

Ying Shi

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13 June 2020

Yanwen Wang

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13 June 2020

Yanmin Zhang

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13 June 2020

Guoliang Hao

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13 June 2020

Jingjing Wu

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13 June 2020

Si Chen

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13 June 2020

Nianguo Dong

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13 June 2020

Ursula Ravens

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13 June 2020

Christopher L-H Huang

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13 June 2020

Henggui Zhang

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13 June 2020

Xin Wang

18

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13 June 2020

language of work or name

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publication date

10 April 2014

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1 August 2017

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

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13 June 2020

3

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13 June 2020

2

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13 June 2020

e000340

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13 June 2020

describes a project that uses

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4187508/fullTextXML

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Atrial fibrillation pathophysiology: implications for management.

1 reference

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6 July 2018

Pak1 as a novel therapeutic target for antihypertrophic treatment in the heart

1 reference

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6 July 2018

Mitogen-activated protein kinase kinase 4 deficiency in cardiomyocytes causes connexin 43 reduction and couples hypertrophic signals to ventricular arrhythmogenesis.

1 reference

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6 July 2018

Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale

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6 July 2018

Atrial remodeling and atrial fibrillation: mechanisms and implications.

1 reference

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6 July 2018

Role of transforming growth factor-beta superfamily signaling pathways in human disease

1 reference

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6 July 2018

Atrial fibrosis: mechanisms and clinical relevance in atrial fibrillation.

1 reference

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Myocardial matrix remodeling and the matrix metalloproteinases: influence on cardiac form and function

1 reference

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6 July 2018

Heterogeneity of IK1 in the mouse heart

1 reference

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6 July 2018

Targeted deletion of the mitogen-activated protein kinase kinase 4 gene in the nervous system causes severe brain developmental defects and premature death

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6 July 2018

Physiological roles of MKK4 and MKK7: insights from animal models

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6 July 2018

Increased vulnerability to atrial fibrillation in transgenic mice with selective atrial fibrosis caused by overexpression of TGF-beta1.

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6 July 2018

Electrophysiological evidence for a gradient of G protein‐gated K+ current in adult mouse atria

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6 July 2018

Atrial cardiomyocyte-specific expression of Cre recombinase driven by an Nppa gene fragment.

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6 July 2018

Mechanism of p38 MAP kinase activation in vivo.

1 reference

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6 July 2018

Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling

1 reference

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JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

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6 July 2018

Signal transduction systems and atrial fibrillation

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Is angiotensin II a proliferative factor of cardiac fibroblasts?

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6 July 2018

Regulation of the ERK subgroup of MAP kinase cascades through G protein-coupled receptors

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6 July 2018

Relating extracellular potentials and their derivatives to anisotropic propagation at a microscopic level in human cardiac muscle. Evidence for electrical uncoupling of side-to-side fiber connections with increasing age.

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6 July 2018

Presence and functional role of the rapidly activating delayed rectifier K(+) current in left and right atria of adult mice

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28 October 2018

Atrial fibrosis and atrial fibrillation: the role of the TGF-β1 signaling pathway.

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28 October 2018

Cardiac-specific deletion of mkk4 reveals its role in pathological hypertrophic remodeling but not in physiological cardiac growth.

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JNK regulates autocrine expression of TGF-beta1.

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28 October 2018

Computer model of action potential of mouse ventricular myocytes.

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28 October 2018

Effects of angiotensin-converting enzyme inhibition on the development of the atrial fibrillation substrate in dogs with ventricular tachypacing-induced congestive heart failure

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28 October 2018

p38 Mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensin II. Role in vascular smooth muscle cell hypertrophy.

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12 December 2020

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An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct

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Identifiers

10.1161/JAHA.113.000340

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13 June 2020

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13 June 2020

1 reference

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13 June 2020

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