NS6180, a new K(Ca) 3.1 channel inhibitor prevents T-cell activation and inflammation in a rat model of inflammatory bowel disease. (Q34293957)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22891655%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

NS6180, a new K(Ca) 3.1 channel inhibitor prevents T-cell activation and inflammation in a rat model of inflammatory bowel disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22891655%20AND%20SRC:MED&resulttype=core&format=json

inflammatory bowel diseases

11 February 2020

main subject

0 references

author name string

D Strøbæk

1

1 reference

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11 February 2020

D T Brown

2

1 reference

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11 February 2020

D P Jenkins

3

1 reference

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11 February 2020

Y-J Chen

4

1 reference

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11 February 2020

N Coleman

5

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11 February 2020

P Chiu

7

1 reference

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11 February 2020

S Jørgensen

8

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11 February 2020

J Demnitz

9

1 reference

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11 February 2020

H Wulff

10

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11 February 2020

P Christophersen

11

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11 February 2020

Yukio Ando

6

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11 February 2020

language of work or name

English

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publication date

1 January 2013

1 reference

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British Journal of Pharmacology

11 February 2020

published in

1 reference

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11 February 2020

volume

168

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11 February 2020

issue

2

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11 February 2020

page(s)

432-444

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Guide to Receptors and Channels (GRAC), 5th edition

11 February 2020

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Negative gating modulation by (R)-N-(benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphthylamine (NS8593) depends on residues in the inner pore vestibule: pharmacological evidence of deep-pore gating of K(Ca)2 channels

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6 July 2018

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Naphtho[1,2-d]thiazol-2-ylamine (SKA-31), a new activator of KCa2 and KCa3.1 potassium channels, potentiates the endothelium-derived hyperpolarizing factor response and lowers blood pressure

6 July 2018

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The intermediate-conductance calcium-activated potassium channel KCa3.1 contributes to atherogenesis in mice and humans

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Selective intermediate-/small-conductance calcium-activated potassium channel (KCNN4) blockers are potent and effective therapeutics in experimental brain oedema and traumatic brain injury caused by acute subdural haematoma

6 July 2018

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K+ channel expression during B cell differentiation: implications for immunomodulation and autoimmunity

6 July 2018

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Selective blockade of T lymphocyte K(+) channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis

6 July 2018

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Delineation of the clotrimazole/TRAM-34 binding site on the intermediate conductance calcium-activated potassium channel, IKCa1

6 July 2018

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6 July 2018

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6 July 2018

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The antifungal antibiotic, clotrimazole, inhibits chloride secretion by human intestinal T84 cells via blockade of distinct basolateral K+ conductances. Demonstration of efficacy in intact rabbit colon and in an in vivo mouse model of cholera

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6 July 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Inhibitory gating modulation of small conductance Ca2+-activated K+ channels by the synthetic compound (R)-N-(benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphtylamine (NS8593) reduces afterhyperpolarizing current in hippocampal CA1 neurons.

21 January 2018

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21 January 2018

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21 January 2018

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IKCa-channel blockers. Part 2: discovery of cyclohexadienes

21 January 2018

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Blocking ion channel KCNN4 alleviates the symptoms of experimental autoimmune encephalomyelitis in mice

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22891655

inferred from PubMed ID database lookup

12 December 2020

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Identifiers

DOI

10.1111/J.1476-5381.2012.02143.X

1 reference

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11 February 2020

1 reference

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11 February 2020

1 reference

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