Adenomatous polyposis coli and hypoxia-inducible factor-1{alpha} have an antagonistic connection (Q34249164)

31 July 2017

Adenomatous polyposis coli and hypoxia-inducible factor-1{alpha} have an antagonistic connection (English)

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31 July 2017

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Niall S Kenneth

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S Rocha

object named as

Sonia Rocha

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Inke Nathke

object named as

Inke Näthke

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author name string

Ian P Newton

1

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PubMed ID

20844082

31 July 2017

Paul L Appleton

3

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31 July 2017

15 September 2010

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Molecular Biology of the Cell

31 July 2017

1 reference

31 July 2017

21

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31 July 2017

21

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31 July 2017

3630-3638

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PubMed ID

20844082

describes a project that uses

31 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2965681/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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An essential role of the HIF-1alpha-c-Myc axis in malignant progression

6 July 2018

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A two-step model for colon adenoma initiation and progression caused by APC loss

6 July 2018

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6 July 2018

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SWI/SNF regulates the cellular response to hypoxia.

6 July 2018

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Regulation of gene expression by hypoxia.

6 July 2018

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Up-regulation of the hypoxia-inducible factor-1 transcriptional pathway in colorectal carcinomas.

6 July 2018

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The role of hypoxia in recurrence following resection of Dukes' B colorectal cancer

6 July 2018

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Hypoxia-inducible factor-1alpha obstructs a Wnt signaling pathway by inhibiting the hARD1-mediated activation of beta-catenin

6 July 2018

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NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha

6 July 2018

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Regulation of hypoxia-inducible factor-1alpha by NF-kappaB

6 July 2018

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The selectivity of autophagy and its role in cell death and survival

6 July 2018

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Cell regulation by the Apc protein Apc as master regulator of epithelia.

6 July 2018

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Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia

6 July 2018

1 reference

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Autophagy in the Pathogenesis of Disease

6 July 2018

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Hypoxia and gastrointestinal disease

6 July 2018

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Hydroxylation of hypoxia-inducible transcription factors and chemical compounds targeting the HIF-alpha hydroxylases

6 July 2018

1 reference

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Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis

6 July 2018

1 reference

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Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxia

6 July 2018

1 reference

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Regulation of p53 tumour suppressor target gene expression by the p52 NF-kappaB subunit

6 July 2018

1 reference

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Regulating cellular oxygen sensing by hydroxylation.

6 July 2018

1 reference

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HIFing the brakes: therapeutic opportunities for treatment of human malignancies

6 July 2018

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Good cop, bad cop: the different faces of NF-kappaB

6 July 2018

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Negative and positive regulation of HIF-1: a complex network

6 July 2018

1 reference

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Tumor-associated NH2-terminal fragments are the most stable part of the adenomatous polyposis coli protein and can be regulated by interactions with COOH-terminal domains.

6 July 2018

1 reference

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Identification of a functional hypoxia-responsive element that regulates the expression of the egl nine homologue 3 (egln3/phd3) gene

6 July 2018

1 reference

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Regulation of NF-kappaB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965681

Regulation of the prolyl hydroxylase domain protein 2 (phd2/egln-1) gene: identification of a functional hypoxia-responsive element

6 July 2018

1 reference

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Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration

6 July 2018

1 reference

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Growth factor-mediated induction of HDM2 positively regulates hypoxia-inducible factor 1alpha expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965681

Crossregulation of NF-kappaB by the APC/GSK-3beta/beta-catenin pathway

6 July 2018

1 reference

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Regulation of RelA (p65) function by the large subunit of replication factor C

6 July 2018

1 reference

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beta-catenin interacts with and inhibits NF-kappa B in human colon and breast cancer

6 July 2018

1 reference

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Deregulated beta-catenin induces a p53- and ARF-dependent growth arrest and cooperates with Ras in transformation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965681

Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment

6 July 2018

1 reference

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Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965681

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965681

Linking colorectal cancer to Wnt signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965681

The relationship between angiogenesis and the immune response in carcinogenesis and the progression of malignant disease.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965681

The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965681

APC mutations occur early during colorectal tumorigenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965681

Roles of hypoxia-inducible factor-1alpha (HIF-1alpha) versus HIF-2alpha in the survival of hepatocellular tumor spheroids.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965681

Wnt/beta-catenin signaling regulates cytokine-induced human inducible nitric oxide synthase expression by inhibiting nuclear factor-kappaB activation in cancer cells.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965681

Hypoxia-inducible factor-1alpha promotes nonhypoxia-mediated proliferation in colon cancer cells and xenografts

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965681

The cross-talk between NF-kappaB and HIF-1: further evidence for a significant liaison

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20844082

12 December 2020

inferred from PubMed ID database lookup

Growth factor signaling permits hypoxia-induced autophagy by a HIF1α-dependent, BNIP3/3L-independent transcriptional program in human cancer cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20844082

12 December 2020

inferred from PubMed ID database lookup

Detailed analysis of genetic alterations in colorectal tumors from patients with and without familial adenomatous polyposis (FAP)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20844082

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1091/MBC.E10-04-0312

1 reference

31 July 2017

1 reference

31 July 2017

1 reference

PubMed ID

20844082