Severity of doxorubicin-induced small intestinal mucositis is regulated by the TLR-2 and TLR-9 pathways (Q34220376)

31 July 2017

Severity of doxorubicin-induced small intestinal mucositis is regulated by the TLR-2 and TLR-9 pathways (English)

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31 July 2017

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Dmitri V Krysko

5

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Peter Vandenabeele

object named as

Peter Vandenabeele

4

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author name string

Agnieszka Kaczmarek

1

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PubMed ID

21960132

31 July 2017

Brigitta M Brinkman

2

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PubMed ID

21960132

31 July 2017

Liesbeth Heyndrickx

3

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31 July 2017

5 December 2011

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31 July 2017

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31 July 2017

226

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31 July 2017

598-608

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31 July 2017

4

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Mucosal barrier injury: biology, pathology, clinical counterparts and consequences of intensive treatment for haematological malignancy: an overview

31 July 2017

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Intestinal damage determines the inflammatory response and early complications in patients receiving conditioning for a stem cell transplantation

21 January 2018

1 reference

The pathobiology of mucositis

21 January 2018

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New thoughts on the initiation of mucositis

21 January 2018

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Characterisation of mucosal changes in the alimentary tract following administration of irinotecan: implications for the pathobiology of mucositis.

21 January 2018

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Is the pathobiology of chemotherapy-induced alimentary tract mucositis influenced by the type of mucotoxic drug administered?

21 January 2018

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Citrulline: a potentially simple quantitative marker of intestinal epithelial damage following myeloablative therapy

21 January 2018

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Monitoring myeloablative therapy-induced small bowel toxicity by serum citrulline concentration: a comparison with sugar permeability tests.

21 January 2018

1 reference

Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing Toll-like receptors

21 January 2018

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Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface

21 January 2018

1 reference

Colitis-associated variant of TLR2 causes impaired mucosal repair because of TFF3 deficiency

21 January 2018

1 reference

Enteroendocrine cells express functional Toll-like receptors

21 January 2018

1 reference

Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis

21 January 2018

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Beta-defensin-2 expression is regulated by TLR signaling in intestinal epithelial cells

21 January 2018

1 reference

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

21 January 2018

1 reference

Toll-like receptors (TLRs) and Nod-like receptors (NLRs) in inflammatory disorders.

21 January 2018

1 reference

Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3).

21 January 2018

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Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3.

21 January 2018

1 reference

The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways

21 January 2018

1 reference

Glycogen synthase kinase 3-β: a master regulator of toll-like receptor-mediated chronic intestinal inflammation

21 January 2018

1 reference

Critical role of toll-like receptor 9 in morphine and Mycobacterium tuberculosis-Induced apoptosis in mice

21 January 2018

1 reference

Toll-like receptor 9 is required for opioid-induced microglia apoptosis

21 January 2018

1 reference

Toll-like receptor 2 is required for opioids-induced neuronal apoptosis

21 January 2018

1 reference

Chemotherapy for cancer causes apoptosis that precedes hypoplasia in crypts of the small intestine in humans

21 January 2018

1 reference

Contributions of mucosal immune cells to methotrexate-induced mucositis.

21 January 2018

1 reference

Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription

21 January 2018

1 reference

A new class of molecular targeted radioprotectors: GSK-3beta inhibitors

21 January 2018

1 reference

Methods for distinguishing apoptotic from necrotic cells and measuring their clearance

21 January 2018

1 reference

TLR-2 and TLR-9 are sensors of apoptosis in a mouse model of doxorubicin-induced acute inflammation

21 January 2018

1 reference

Inhibitors of TLR-9 act on multiple cell subsets in mouse and man in vitro and prevent death in vivo from systemic inflammation

21 January 2018

1 reference

21 January 2018

The renaissance of GSK3

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MyD88/TLR9 mediated immunopathology and gut microbiota dynamics in a novel murine model of intestinal graft-versus-host disease

21 January 2018

1 reference

Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function

21 January 2018

1 reference

Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells

21 January 2018

1 reference

Flagellin administration protects gut mucosal tissue from irradiation-induced apoptosis via MKP-7 activity.

21 January 2018

1 reference

Flagellin treatment protects against chemicals, bacteria, viruses, and radiation.

21 January 2018

1 reference

An agonist of toll-like receptor 5 has radioprotective activity in mouse and primate models

21 January 2018

1 reference

Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function.

21 January 2018

1 reference

Stimulation of human Toll-like receptor (TLR) 2 and TLR6 with membrane lipoproteins of Mycoplasma fermentans induces apoptotic cell death after NF-kappa B activation

21 January 2018

1 reference

TLR4, but not TLR2, signals autoregulatory apoptosis of cultured microglia: a critical role of IFN-beta as a decision maker

21 January 2018

1 reference

The glamour and gloom of glycogen synthase kinase-3

21 January 2018

1 reference

Toll-like receptor signalling

21 January 2018

1 reference

Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists

21 January 2018

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In vivo CpG DNA/toll-like receptor 9 interaction induces regulatory properties in CD4+CD62L+ T cells which prevent intestinal inflammation in the SCID transfer model of colitis

21 January 2018

1 reference

CpG motifs of bacterial DNA essentially contribute to the perpetuation of chronic intestinal inflammation

21 January 2018

1 reference

GSK3: an in-Toll-erant protein kinase?

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/PATH.3009

1 reference

31 July 2017

1 reference

PubMed ID

21960132