Xanthatin induces cell cycle arrest at G2/M checkpoint and apoptosis via disrupting NF-κB pathway in A549 non-small-cell lung cancer cells. (Q34208445)

31 July 2017

Xanthatin induces cell cycle arrest at G2/M checkpoint and apoptosis via disrupting NF-κB pathway in A549 non-small-cell lung cancer cells (English)

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Lei Zhang

1

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Junshan Ruan

2

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Linggeng Yan

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Weidong Li

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Yu Wu

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Li Tao

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Feng Zhang

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Shizhong Zheng

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Aiyun Wang

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Yin Lu

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language of work or name

English

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publication date

26 March 2012

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31 July 2017

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13 May 2020

volume

17

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issue

4

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13 May 2020

page(s)

3736-3750

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Creative Commons Attribution 4.0 International

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copyright license

start time

26 March 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Natural products for cancer chemotherapy

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

Xanthane sesquiterpenoids: structure, synthesis and biological activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

Anti-cancer potential of sesquiterpene lactones: bioactivity and molecular mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

What made sesquiterpene lactones reach cancer clinical trials?

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

Xanthatin and xanthinosin from the burs of Xanthium strumarium L. as potential anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

Cell survival, cell death and cell cycle pathways are interconnected: implications for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

Inflammation: a driving force speeds cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 expression by xanthanolides isolated from Xanthium strumarium

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

p53 and E2f: partners in life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

Anticancer therapy targeting the apoptotic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

The role of the Bcl-2 protein family in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

Caspases: pharmacological manipulation of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

Novel anti-ulcer alpha,beta-unsaturated lactones inhibit compound 48/80-induced mast cell degranulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

(--)-Xanthatin selectively induces GADD45γ and stimulates caspase-independent cell death in human breast cancer MDA-MB-231 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

Targeting the cell cycle: a new approach to cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

Telomere-mediated genomic instability and the clinico-pathological parameters in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

Caspases at the crossroads of immune-cell life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

Targeted induction of apoptosis in cancer management: the emerging role of tumor necrosis factor-related apoptosis-inducing ligand receptor activating agents

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

Cell cycle checkpoint signaling through the ATM and ATR kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

Chk1 and Chk2 kinases in checkpoint control and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

G2 checkpoint abrogation and checkpoint kinase-1 targeting in the treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

The E2F1/Rb and p53/MDM2 pathways in DNA repair and apoptosis: understanding the crosstalk to develop novel strategies for prostate cancer radiotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

NF-kappaB: a potential target for cancer chemoprevention and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

Controlling signaling with a specifically designed Gi-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES17043736

G2 checkpoint abrogators as anticancer drugs

21 January 2018

1 reference

12 December 2020

Chemical constituents from Xanthium mongolicum

1 reference

12 December 2020

Xanthanolides with antitumour activity from Xanthium italicum

1 reference

12 December 2020

Sesquiterpene lactones specifically inhibit activation of NF-kappa B by preventing the degradation of I kappa B-alpha and I kappa B-beta

1 reference

12 December 2020

Cytotoxic activity of xanthatin and the crude extracts of Xanthium strumarium

1 reference

12 December 2020

10.3390/MOLECULES17043736

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6268665&resulttype=core&format=json

13 May 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6268665&resulttype=core&format=json

13 May 2020

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