Gamma-secretase-regulated proteolysis of the Notch receptor by mitochondrial intermediate peptidase (Q34193760)

31 July 2017

Gamma-secretase-regulated proteolysis of the Notch receptor by mitochondrial intermediate peptidase (English)

1 reference

31 July 2017

1 reference

Sheu-Fen Lee

1

1 reference

31 July 2017

Bhooma Srinivasan

2

1 reference

31 July 2017

Chantelle F Sephton

3

1 reference

31 July 2017

Daniel R Dries

4

1 reference

31 July 2017

Bing Wang

5

1 reference

31 July 2017

Cong Yu

6

1 reference

31 July 2017

Yun Wang

7

1 reference

31 July 2017

Colleen M Dewey

8

1 reference

31 July 2017

Sanjiv Shah

9

1 reference

31 July 2017

Jin Jiang

10

1 reference

31 July 2017

Gang Yu

11

1 reference

31 July 2017

language of work or name

English

0 references

publication date

17 June 2011

1 reference

Journal of Biological Chemistry

31 July 2017

1 reference

31 July 2017

286

1 reference

31 July 2017

31

1 reference

31 July 2017

27447-27453

1 reference

Mitochondrial γ-secretase participates in the metabolism of mitochondria-associated amyloid precursor protein

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Notch-activated signaling cascade interacts with mitochondrial remodeling proteins to regulate cell survival

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Down-regulation of the Notch pathway mediated by a gamma-secretase inhibitor induces anti-tumour effects in mouse models of T-cell leukaemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Function of mitochondrial Stat3 in cellular respiration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

ChIP-on-chip significance analysis reveals large-scale binding and regulation by human transcription factor oncogenes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

RAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription Complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Molecular separation of two signaling pathways for the receptor, Notch

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Regulation of Notch signaling by dynamic changes in the precision of S3 cleavage of Notch-1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Crossing paths with Notch in the hyper-network

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Notch signalling: a simple pathway becomes complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Notch signalling regulates stem cell numbers in vitro and in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Enigma, a mitochondrial protein affecting lifespan and oxidative stress response in Drosophila

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Notch signalling in vertebrate neural development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Recent insights into the role of Notch signaling in tumorigenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Notch in the pathway: the roles of Notch signaling in neural crest development.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Monoubiquitination and endocytosis direct gamma-secretase cleavage of activated Notch receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Notch activation induces apoptosis in neural progenitor cells through a p53-dependent pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Notch1 can contribute to viral-induced transformation of primary human keratinocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

A conserved GXXXG motif in APH-1 is critical for assembly and activity of the gamma-secretase complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

The role of Notch in tumorigenesis: oncogene or tumour suppressor?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Molecular chaperones Hsp90 and Hsp70 deliver preproteins to the mitochondrial import receptor Tom70

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Extensive feature detection of N-terminal protein sorting signals

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Notch signaling: from the outside in

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Cell cycle arrest and apoptosis induced by Notch1 in B cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Predicting subcellular localization of proteins based on their N-terminal amino acid sequence

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Presenilin is required for activity and nuclear access of Notch in Drosophila

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Cutting edge: protective effects of notch-1 on TCR-induced apoptosis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Nuclear access and action of notch in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Computational method to predict mitochondrially imported proteins and their targeting sequences

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Analysis of dominant enhancers and suppressors of activated Notch in Drosophila

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Signalling downstream of activated mammalian Notch

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

The action of the notchlocus in Drosophila melanogaster. II. Biochemical effects of recessive lethals on mitochondrial enzymes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

Nicastrin functions as a gamma-secretase-substrate receptor

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.243154

The suppressor of hairless protein participates in notch receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.243154

Mitochondrial dysfunction associated with a mutation in the Notch3 gene in a CADASIL family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.243154

A novel NOTCH3 frameshift deletion and mitochondrial abnormalities in a patient with CADASIL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.243154

Total inactivation of gamma-secretase activity in presenilin-deficient embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.243154

Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.243154

Notch1 enhances B-cell receptor-induced apoptosis in mature activated B cells without affecting cell cycle progression and surface IgM expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.243154

Local induction of patterning and programmed cell death in the developing Drosophila retina.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149338

The action of the notch locus in Drosophila melanogaster. I. Effects of the notch8 deficiency on mitochondrial enzymes

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21685396

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Import of proteins into mitochondria. Energy-dependent, two-step processing of the intermembrane space enzyme cytochrome b2 by isolated yeast mitochondria

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21685396

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The Notch transcription activation complex makes its move

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21685396

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M111.243154

1 reference

31 July 2017

1 reference

31 July 2017

1 reference