A heterotrimeric death domain complex in Toll signaling (Q34190298)

31 July 2017

A heterotrimeric death domain complex in Toll signaling (English)

1 reference

31 July 2017

1 reference

GOA release 2020-03-11

Pelle Dmel_CG5974

1 reference

GOA release 2020-03-11

Tube Dmel_CG10520

1 reference

GOA release 2020-03-11

author name string

Huaiyu Sun

1

1 reference

31 July 2017

Benjamin N Bristow

2

1 reference

31 July 2017

Guowei Qu

3

1 reference

31 July 2017

Steven A Wasserman

4

1 reference

31 July 2017

language of work or name

English

0 references

publication date

26 September 2002

1 reference

Proceedings of the National Academy of Sciences of the United States of America

31 July 2017

1 reference

31 July 2017

99

1 reference

31 July 2017

12871-12876

1 reference

31 July 2017

20

1 reference

IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

Drosophila innate immunity: an evolutionary perspective

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

Drosophila MyD88 is an adapter in the Toll signaling pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

NF-kappaB signaling pathways in mammalian and insect innate immunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

The death domain superfamily: a tale of two interfaces?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-kappaB-dependent innate immune responses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

Physical and functional interactions between Drosophila TRAF2 and Pelle kinase contribute to Dorsal activation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

The antibacterial arm of the drosophila innate immune response requires an IkappaB kinase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

Toll signaling: the enigma variations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

The Drosophila tumor necrosis factor receptor-associated factor-1 (DTRAF1) interacts with Pelle and regulates NFkappaB activity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

Three-dimensional structure of a complex between the death domains of Pelle and Tube

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

MyD88, an adapter protein involved in interleukin-1 signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

MyD88: an adapter that recruits IRAK to the IL-1 receptor complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

A multimeric complex and the nuclear targeting of the Drosophila Rel protein Dorsal

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

An activity-dependent network of interactions links the Rel protein Dorsal with its cytoplasmic regulators.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

A conserved signaling pathway: the Drosophila toll-dorsal pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

IRAK: a kinase associated with the interleukin-1 receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

A novel domain within the 55 kd TNF receptor signals cell death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

Genetic characterization of tube and pelle, genes required for signaling between Toll and dorsal in the specification of the dorsal-ventral pattern of the Drosophila embryo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

Contenders in FasL/TNF death signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

Ventralization of the Drosophila embryo by deletion of extracellular leucine-rich repeats in the Toll protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

The death domain: a module shared by proteins with diverse cellular functions.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

Genetic and molecular characterization of tube, a Drosophila gene maternally required for embryonic dorsoventral polarity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

Characterization of the Drosophila cactus locus and analysis of interactions between cactus and dorsal proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

The Rel protein DIF mediates the antifungal but not the antibacterial host defense in Drosophila

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.202396399

pelle encodes a protein kinase required to establish dorsoventral polarity in the Drosophila embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.202396399

A Drosophila TNF-receptor-associated factor (TRAF) binds the ste20 kinase Misshapen and activates Jun kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.202396399

Complete structural characterisation of the mammalian and Drosophila TRAF genes: implications for TRAF evolution and the role of RING finger splice variants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.202396399

Role of Drosophila IKK gamma in a toll-independent antibacterial immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.202396399

Activation of the kinase Pelle by Tube in the dorsoventral signal transduction pathway of Drosophila embryo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.202396399

The protein kinase Pelle mediates feedback regulation in the Drosophila Toll signaling pathway.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

Phosphorylation modulates direct interactions between the Toll receptor, Pelle kinase and Tube.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

Interaction of the pelle kinase with the membrane-associated protein tube is required for transduction of the dorsoventral signal in Drosophila embryos.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130552

A docking model of key components of the DISC complex: death domain superfamily interactions redefined

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12351681

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.202396399

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference