Stability and the evolvability of function in a model protein (Q34185523)

31 July 2017

Stability and the evolvability of function in a model protein (English)

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31 July 2017

1

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31 July 2017

3

Frances H Arnold

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31 July 2017

Christoph Adami

4

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Claus O. Wilke

series ordinal

2

object named as

Claus O Wilke

1 reference

PubMed ID

15111394

31 July 2017

language of work or name

English

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publication date

1 May 2004

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31 July 2017

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31 July 2017

86

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31 July 2017

2758-2764

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31 July 2017

5

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Perspectives on protein evolution from simple exact models.

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

Roles of mutation and recombination in the evolution of protein thermodynamics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

Evolution of an antibiotic resistance enzyme constrained by stability and activity trade-offs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

Recombinatoric exploration of novel folded structures: a heteropolymer-based model of protein evolutionary landscapes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

Protein topology and stability define the space of allowed sequences.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

Evolution of functionality in lattice proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

Functional proteins from a random-sequence library

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

How enzymes adapt: lessons from directed evolution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

Modeling evolutionary landscapes: mutational stability, topology, and superfunnels in sequence space

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

Directed evolution of a thermostable esterase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

How evolution makes proteins fold quickly

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

Enzyme engineering reaches the boiling point

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

Ligand binding to proteins: the binding landscape model

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

Engineering of stable and fast-folding sequences of model proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

Exploring conformational space with a simple lattice model for protein structure

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

Evolution-like selection of fast-folding model proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

A relationship between protein stability and protein function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

Hyperthermophiles: taking the heat and loving it.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

5 July 2018

Proteins and temperature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

Principles of protein folding--a perspective from simple exact models.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

Cooperatively folded proteins in random sequence libraries

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

Principles that govern the folding of protein chains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

Hiking in the energy landscape in sequence space: a bumpy road to good folders.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

Neutral evolution of model proteins: diffusion in sequence space and overdispersion

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

Protein folding mechanisms and the multidimensional folding funnel.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

Step-wise mutation of barnase to binase. A procedure for engineering increased stability of proteins and an experimental analysis of the evolution of protein stability

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

Stability and function: two constraints in the evolution of barstar and other proteins

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304146

Structurally constrained protein evolution: results from a lattice simulation

28 October 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2804%2974329-5

Stability of Designed Proteins against Mutations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2804%2974329-5

Protein design: a perspective from simple tractable models.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2804%2974329-5

The distribution of structures in evolving protein populations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2804%2974329-5

Why are proteins marginally stable?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2804%2974329-5

The evolutionary landscape of functional model proteins

7 January 2021

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15111394

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/S0006-3495(04)74329-5

1 reference

31 July 2017

1 reference

1 reference

31 July 2017

1 reference

PubMed ID

15111394