The genetics and genomics of cancer (Q34180336)

31 July 2017

title

The genetics and genomics of cancer (English)

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31 July 2017

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2

Joe Gray

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31 July 2017

Allan Balmain

1

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31 July 2017

Bruce Ponder

series ordinal

3

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31 July 2017

publication date

1 March 2003

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31 July 2017

language of work or name

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31 July 2017

volume

33 Suppl

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31 July 2017

page(s)

238-244

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publication type of scholarly work

31 July 2017

review article

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Mutation and cancer: statistical study of retinoblastoma

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7 January 2021

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

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7 January 2021

The Causes of Cancer: Quantitative Estimates of Avoidable Risks of Cancer in the United States Today

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Cancer epidemiology in the last century and the next decade

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CANCER MORTALITY AMONG JAPANESE ISSEI AND NISEI OF CALIFORNIA

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Inheritance of human breast cancer: evidence for autosomal dominant transmission in high-risk families

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Linkage of early-onset familial breast cancer to chromosome 17q21

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7 January 2021

The retinoblastoma protein and cell cycle control

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7 January 2021

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

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7 January 2021

T antigen is bound to a host protein in SY40-transformed cells

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7 January 2021

Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas

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7 January 2021

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

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7 January 2021

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

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7 January 2021

Cancer susceptibility and the functions of BRCA1 and BRCA2

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7 January 2021

Genome maintenance mechanisms for preventing cancer

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7 January 2021

Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas

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7 January 2021

Neurofibromas in NF1: Schwann cell origin and role of tumor environment

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7 January 2021

Will Genetics Revolutionize Medicine?

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7 January 2021

The new genetics in clinical practice

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7 January 2021

Polygenic susceptibility to breast cancer and implications for prevention

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7 January 2021

Environmental and heritable factors in the causation of cancer--analyses of cohorts of twins from Sweden, Denmark, and Finland

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7 January 2021

After BRCA1 and BRCA2-what next? Multifactorial segregation analyses of three-generation, population-based Australian families affected by female breast cancer

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7 January 2021

A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genes

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7 January 2021

Breast cancer susceptibility-A new look at an old model

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7 January 2021

Association study designs for complex diseases

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7 January 2021

Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease

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7 January 2021

The structure of haplotype blocks in the human genome

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7 January 2021

Genomics. New mapping project splits the community

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7 January 2021

Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus

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7 January 2021

Cancer resistance genes in mice: models for the study of tumour modifiers

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7 January 2021

Complexity of lung cancer modifiers: mapping of thirty genes and twenty-five interactions in half of the mouse genome.

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7 January 2021

A subset of skin tumor modifier loci determines survival time of tumor-bearing mice.

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7 January 2021

Complex interactions of new quantitative trait loci, Sluc1, Sluc2, Sluc3, and Sluc4, that influence the susceptibility to lung cancer in the mouse

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7 January 2021

Gene interaction and single gene effects in colon tumour susceptibility in mice

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7 January 2021

Interfaces between the detection, signaling, and repair of DNA damage

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7 January 2021

Maintenance of genome stability in Saccharomyces cerevisiae

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7 January 2021

Connecting chromosomes, crisis, and cancer

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7 January 2021

Genetic instabilities in human cancers

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7 January 2021

How nucleotide excision repair protects against cancer

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7 January 2021

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

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7 January 2021

Microsatellite instability in cancer of the proximal colon

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7 January 2021

Hypermutability and mismatch repair deficiency in RER+ tumor cells

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7 January 2021

Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype

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7 January 2021

Telomere reduction in human colorectal carcinoma and with ageing

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7 January 2021

Identification of a telomeric DNA sequence in Trypanosoma brucei

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7 January 2021

Mutations of mitotic checkpoint genes in human cancers

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7 January 2021

Chromosome segregation and cancer: cutting through the mystery

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7 January 2021

APC, signal transduction and genetic instability in colorectal cancer

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7 January 2021

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

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7 January 2021

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

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7 January 2021

Abnormal centrosome amplification in the absence of p53.

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7 January 2021

Surfing the p53 network

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7 January 2021

A genetic model for colorectal tumorigenesis

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7 January 2021

The Clonal Evolution of Tumor Cell Populations

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7 January 2021

Integration of positive and negative growth signals during ras pathway activation in vivo

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7 January 2021

Debate surges over the origins of genomic defects in cancer

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7 January 2021

Frequent clones of p53-mutated keratinocytes in normal human skin

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7 January 2021

Loss of heterozygosity in normal tissue adjacent to breast carcinomas

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7 January 2021

High frequency of loss of heterozygosity in actinic keratoses, a usually benign disease

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7 January 2021

Histopathologic types of benign breast lesions and the risk of breast cancer: case-control study

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7 January 2021

The malignant capacity of skin tumours induced by expression of a mutant H-ras transgene depends on the cell type targeted

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7 January 2021

Fluorescence in situ hybridization with human chromosome-specific libraries: detection of trisomy 21 and translocations of chromosome 4.

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7 January 2021

Genome changes and gene expression in human solid tumors

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7 January 2021

Restriction landmark genomic scanning method and its various applications

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7 January 2021

Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors

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7 January 2021

Cloning the differences between two complex genomes

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7 January 2021

Integrated genomic and epigenomic analyses pinpoint biallelic gene inactivation in tumors

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7 January 2021

Mutations of the BRAF gene in human cancer

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7 January 2021

Quantitative monitoring of gene expression patterns with a complementary DNA microarray

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7 January 2021

Utility of Accurate Mass Tags for Proteome-Wide Protein Identification

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7 January 2021

Structural organization of the bcr gene and its role in the Ph' translocation

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7 January 2021

Modelling haematopoietic malignancies in the mouse and therapeutical implications

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7 January 2021

Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome

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7 January 2021

ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization

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7 January 2021

First-line Herceptin monotherapy in metastatic breast cancer

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7 January 2021

Discovery of a novel Raf kinase inhibitor

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7 January 2021

Cancer: new-age tumour suppressors

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7 January 2021

Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

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7 January 2021

Altered methylation patterns in cancer cell genomes: cause or consequence?

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7 January 2021

The fundamental role of epigenetic events in cancer

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7 January 2021

Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation

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7 January 2021

Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency.

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7 January 2021

The murine gene p27Kip1 is haplo-insufficient for tumour suppression

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7 January 2021

Dmp1 is haplo-insufficient for tumor suppression and modifies the frequencies of Arf and p53 mutations in Myc-induced lymphomas

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7 January 2021

Parental bias of Ki-ras oncogenes detected in lung tumors from mouse hybrids

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7 January 2021

Allele-specific loss or imbalance of chromosomes 9, 15, and 16 in B-cell tumors from interspecific F1 hybrid mice carrying Emu-c-myc or N-myc transgenes

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7 January 2021

Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas

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7 January 2021

Emerging molecular markers of cancer

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7 January 2021

Analysis of minichromosome maintenance proteins as a novel method for detection of colorectal cancer in stool

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7 January 2021

A gene-expression signature as a predictor of survival in breast cancer

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7 January 2021

Error and attack tolerance of complex networks

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7 January 2021

Identifiers

DOI

10.1038/NG1107

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31 July 2017

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