Modification of the cysteine residues in IkappaBalpha kinase and NF-kappaB (p65) by xanthohumol leads to suppression of NF-kappaB-regulated gene products and potentiation of apoptosis in leukemia cells (Q34162807)

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English	Modification of the cysteine residues in IkappaBalpha kinase and NF-kappaB (p65) by xanthohumol leads to suppression of NF-kappaB-regulated gene products and potentiation of apoptosis in leukemia cells	scientific article

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25 December 2019

Modification of the cysteine residues in IkappaBalpha kinase and NF-kappaB (p65) by xanthohumol leads to suppression of NF-kappaB-regulated gene products and potentiation of apoptosis in leukemia cells (English)

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25 December 2019

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Kuzhuvelil B Harikumar

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Ajaikumar B Kunnumakkara

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25 December 2019

Kwang S Ahn

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Preetha Anand

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25 December 2019

Sunil Krishnan

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Sushovan Guha

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Bharat B Aggarwal

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24 October 2008

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25 December 2019

2003-2013

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25 December 2019

Xanthohumol inhibits inflammatory factor production and angiogenesis in breast cancer xenografts.

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1 reference

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Helenanolide-type sesquiterpene lactones--III. Rates and stereochemistry in the reaction of helenalin and related helenanolides with sulfhydryl containing biomolecules

1 reference

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inferred from PubMed ID database lookup

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1 reference

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inferred from PubMed ID database lookup

Butein, a tetrahydroxychalcone, inhibits nuclear factor (NF)-kappaB and NF-kappaB-regulated gene expression through direct inhibition of IkappaBalpha kinase beta on cysteine 179 residue

1 reference

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Epidermal growth factor (EGF) activates nuclear factor-kappaB through IkappaBalpha kinase-independent but EGF receptor-kinase dependent tyrosine 42 phosphorylation of IkappaBalpha

1 reference

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inferred from PubMed ID database lookup

Cysteine-179 of IkappaB kinase beta plays a critical role in enzyme activation by promoting phosphorylation of activation loop serines

1 reference

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1 reference

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Identifiers

10.1182/BLOOD-2008-04-151944

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25 December 2019

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25 December 2019

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25 December 2019

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