Physical basis behind achondroplasia, the most common form of human dwarfism (Q34144662)

31 July 2017

Physical basis behind achondroplasia, the most common form of human dwarfism (English)

1 reference

31 July 2017

3

Kalina Hristova

1 reference

31 July 2017

Lijuan He

1

1 reference

31 July 2017

William Horton

series ordinal

2

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31 July 2017

language of work or name

English

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publication date

12 July 2010

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Journal of Biological Chemistry

31 July 2017

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31 July 2017

285

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31 July 2017

39

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31 July 2017

30103-30114

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describes a project that uses

31 July 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2943285/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Receptor tyrosine kinase transmembrane domains: Function, dimer structure and dimerization energetics

1 reference

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28 July 2018

1 reference

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The localization of FGFR3 mutations causing thanatophoric dysplasia type I differentially affects phosphorylation, processing and ubiquitylation of the receptor

28 July 2018

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Insights into the role of heparan sulphate in fibroblast growth factor signalling

28 July 2018

1 reference

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Role of receptor tyrosine kinase transmembrane domains in cell signaling and human pathologies

28 July 2018

1 reference

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Cellular signaling by fibroblast growth factor receptors

28 July 2018

1 reference

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Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity

28 July 2018

1 reference

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Defective lysosomal targeting of activated fibroblast growth factor receptor 3 in achondroplasia

28 July 2018

1 reference

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FGF receptors ubiquitylation: dependence on tyrosine kinase activity and role in downregulation

28 July 2018

1 reference

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Ligand-induced, receptor-mediated dimerization and activation of EGF receptor

28 July 2018

1 reference

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Ligand-independent dimer formation of epidermal growth factor receptor (EGFR) is a step separable from ligand-induced EGFR signaling

28 July 2018

1 reference

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Rotational coupling of the transmembrane and kinase domains of the Neu receptor tyrosine kinase

28 July 2018

1 reference

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The molecular and genetic basis of fibroblast growth factor receptor 3 disorders: the achondroplasia family of skeletal dysplasias, Muenke craniosynostosis, and Crouzon syndrome with acanthosis nigricans

28 July 2018

1 reference

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FGFs, heparan sulfate and FGFRs: complex interactions essential for development

28 July 2018

1 reference

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The transmembrane mutation G380R in fibroblast growth factor receptor 3 uncouples ligand-mediated receptor activation from down-regulation

28 July 2018

1 reference

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Effect of transmembrane and kinase domain mutations on fibroblast growth factor receptor 3 chimera signaling in PC12 cells. A model for the control of receptor tyrosine kinase activation

28 July 2018

1 reference

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FGFR activation in skeletal disorders: too much of a good thing

28 July 2018

1 reference

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Activation of FGF receptors by mutations in the transmembrane domain

28 July 2018

1 reference

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Improved prediction for the structure of the dimeric transmembrane domain of glycophorin A obtained through global searching

28 July 2018

1 reference

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Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3.

28 July 2018

1 reference

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Constitutive activation of fibroblast growth factor receptor 3 by the transmembrane domain point mutation found in achondroplasia

28 July 2018

1 reference

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Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943285

Common and distinct elements in cellular signaling via EGF and FGF receptors

28 July 2018

1 reference

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Novel fibroblast growth factor receptor 3 (FGFR3) mutations in bladder cancer previously identified in non-lethal skeletal disorders

21 January 2018

1 reference

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The achondroplasia mutation does not alter the dimerization energetics of the fibroblast growth factor receptor 3 transmembrane domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.094086

FGFR3 dimer stabilization due to a single amino acid pathogenic mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.094086

Pathogenic activation of receptor tyrosine kinases in mammalian membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.094086

Signal transduction. Autoinhibition control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.094086

Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.094086

Computational searching and mutagenesis suggest a structure for the pentameric transmembrane domain of phospholamban

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.094086

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.094086

Skeletal growth in achondroplasia

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20624921

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M109.094086

1 reference

31 July 2017

1 reference

31 July 2017

1 reference