Effect of transmembrane and kinase domain mutations on fibroblast growth factor receptor 3 chimera signaling in PC12 cells. A model for the control of receptor tyrosine kinase activation (Q28609662)

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English	Effect of transmembrane and kinase domain mutations on fibroblast growth factor receptor 3 chimera signaling in PC12 cells. A model for the control of receptor tyrosine kinase activation	scientific journal article

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scholarly article

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3 February 2017

Effect of transmembrane and kinase domain mutations on fibroblast growth factor receptor 3 chimera signaling in PC12 cells. A model for the control of receptor tyrosine kinase activation (English)

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3 February 2017

transmembrane protein

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author name string

S. Raffioni

1

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3 February 2017

Y. Z. Zhu

2

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3 February 2017

R. A. Bradshaw

3

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3 February 2017

L. M. Thompson

4

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3 February 2017

language of work or name

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publication date

25 December 1998

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3 February 2017

Journal of Biological Chemistry

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3 February 2017

273

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3 February 2017

52

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3 February 2017

35250–35259

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3 February 2017

The heparin-binding (fibroblast) growth factor family of proteins

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21 January 2018

Fibroblast growth factor receptor tyrosine kinases: molecular analysis and signal transduction

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Promiscuity of fibroblast growth factor receptors

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21 January 2018

Growth factor signaling by receptor tyrosine kinases

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21 January 2018

Fibroblast growth factor receptors: lessons from the genes

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21 January 2018

FGFR activation in skeletal disorders: too much of a good thing

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21 January 2018

Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia

1 reference

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21 January 2018

Mutations in the gene encoding fibroblast growth factor receptor-3 in achondroplasia

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21 January 2018

Thanatophoric dysplasia (types I and II) caused by distinct mutations in fibroblast growth factor receptor 3.

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21 January 2018

Common mutations in the fibroblast growth factor receptor 3 (FGFR 3) gene account for achondroplasia, hypochondroplasia, and thanatophoric dwarfism

1 reference

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21 January 2018

Molecular, radiologic, and histopathologic correlations in thanatophoric dysplasia

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21 January 2018

A recurrent mutation in the tyrosine kinase domain of fibroblast growth factor receptor 3 causes hypochondroplasia

1 reference

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21 January 2018

Missense FGFR3 mutations create cysteine residues in thanatophoric dwarfism type I (TD1)

1 reference

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21 January 2018

Another mutation that results in the substitution of an unpaired cysteine residue in the extracellular domain of FGFR3 in thanatophoric dysplasia type I

1 reference

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21 January 2018

Stop codon FGFR3 mutations in thanatophoric dwarfism type 1.

1 reference

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21 January 2018

Fibroblast growth factor receptor 3 (FGFR3) transmembrane mutation in Crouzon syndrome with acanthosis nigricans

1 reference

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21 January 2018

A recurrent mutation, ala391glu, in the transmembrane region of FGFR3 causes Crouzon syndrome and acanthosis nigricans

1 reference

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21 January 2018

A gene encoding a fibroblast growth factor receptor isolated from the Huntington disease gene region of human chromosome 4.

1 reference

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21 January 2018

Unique expression pattern of the FGF receptor 3 gene during mouse organogenesis

1 reference

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21 January 2018

Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3.

1 reference

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21 January 2018

Fibroblast growth factor receptor 3 is a negative regulator of bone growth

1 reference

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21 January 2018

Constitutive receptor activation by Crouzon syndrome mutations in fibroblast growth factor receptor (FGFR)2 and FGFR2/Neu chimeras

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21 January 2018

Activation of FGF receptors by mutations in the transmembrane domain

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21 January 2018

Profound ligand-independent kinase activation of fibroblast growth factor receptor 3 by the activation loop mutation responsible for a lethal skeletal dysplasia, thanatophoric dysplasia type II

1 reference

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21 January 2018

Graded activation of fibroblast growth factor receptor 3 by mutations causing achondroplasia and thanatophoric dysplasia

1 reference

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21 January 2018

Ligand-independent activation of fibroblast growth factor receptors by point mutations in the extracellular, transmembrane, and kinase domains

1 reference

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21 January 2018

Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism

1 reference

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21 January 2018

Mutations causing achondroplasia and thanatophoric dysplasia alter bFGF-induced calcium signals in human diploid fibroblasts

1 reference

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21 January 2018

Chimeras of the native form or achondroplasia mutant (G375C) of human fibroblast growth factor receptor 3 induce ligand-dependent differentiation of PC12 cells

1 reference

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21 January 2018

High-efficiency transformation of mammalian cells by plasmid DNA

1 reference

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21 January 2018

FGF signal transduction in PC12 cells: comparison of the responses induced by endogenous and chimeric receptors

1 reference

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21 January 2018

Isolation of an additional member of the fibroblast growth factor receptor family, FGFR-3

1 reference

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21 January 2018

Intracellular signaling pathways activated by neurotrophic factors

1 reference

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A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway

1 reference

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21 January 2018

Suc1-associated neurotrophic factor target (SNT) protein is a major FGF-stimulated tyrosine phosphorylated 90-kDa protein which binds to the SH2 domain of GRB2

1 reference

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21 January 2018

SNT, a differentiation-specific target of neurotrophic factor-induced tyrosine kinase activity in neurons and PC12 cells

1 reference

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Persistence of dimerization and enzymatic activity of epidermal growth factor receptor in the absence of epidermal growth factor

1 reference

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21 January 2018

Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism

1 reference

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21 January 2018

The heparan sulfate-fibroblast growth factor family: diversity of structure and function.

1 reference

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21 January 2018

A glycine 375-to-cysteine substitution in the transmembrane domain of the fibroblast growth factor receptor-3 in a newborn with achondroplasia

1 reference

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21 January 2018

Fibroblast growth factor receptor 3 mutations promote apoptosis but do not alter chondrocyte proliferation in thanatophoric dysplasia

1 reference

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21 January 2018

Immunoglobulin-like domain 4-mediated receptor-receptor interactions contribute to platelet-derived growth factor-induced receptor dimerization

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21 January 2018

Identifiers

10.1074/JBC.273.52.35250

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1 reference

3 February 2017

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