Activation of STAT proteins and growth control (Q34136104)

31 July 2017

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title

Activation of STAT proteins and growth control (English)

1 reference

31 July 2017

Bromberg JF

1

1 reference

PubMed ID

11169589

31 July 2017

language of work or name

English

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publication date

1 February 2001

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31 July 2017

9

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based on heuristic

inferred from page(s)

published in

BioEssays

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31 July 2017

23

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31 July 2017

161-169

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31 July 2017

2

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STATs and gene regulation

31 July 2017

1 reference

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Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA

21 January 2018

1 reference

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A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1.

21 January 2018

1 reference

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Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

21 January 2018

1 reference

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Ser727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation

21 January 2018

1 reference

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Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling

21 January 2018

1 reference

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The linker domain of Stat1 is required for gamma interferon-driven transcription

21 January 2018

1 reference

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Cooperative DNA binding and sequence-selective recognition conferred by the STAT amino-terminal domain

21 January 2018

1 reference

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The significance of tetramerization in promoter recruitment by Stat5.

21 January 2018

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Functional interactions between Stat5 and the glucocorticoid receptor

21 January 2018

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Interacting regions in Stat3 and c-Jun that participate in cooperative transcriptional activation

21 January 2018

1 reference

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Structure and function of the interferon-beta enhanceosome

21 January 2018

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Ligand-induced assembly and activation of the gamma interferon receptor in intact cells

21 January 2018

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STATs: signal transducers and activators of transcription

21 January 2018

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The IFN gamma receptor: a paradigm for cytokine receptor signaling

21 January 2018

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Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses

21 January 2018

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Jak2 is essential for signaling through a variety of cytokine receptors

21 January 2018

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Developmental defects of lymphoid cells in Jak3 kinase-deficient mice.

21 January 2018

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Roles of JAKs in activation of STATs and stimulation of c-fos gene expression by epidermal growth factor

21 January 2018

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Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptor

21 January 2018

1 reference

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RANTES and MIP-1alpha activate stats in T cells

21 January 2018

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Stat3-mediated transformation of NIH-3T3 cells by the constitutively active Q205L Galphao protein.

21 January 2018

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A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia

21 January 2018

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21 January 2018

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Differences in phosphorylation of the IL-2R associated JAK/STAT proteins between HTLV-I(+), IL-2-independent and IL-2-dependent cell lines and uncultured leukemic cells from patients with adult T-cell lymphoma/leukemia

21 January 2018

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Differential regulation of the alpha/beta interferon-stimulated Jak/Stat pathway by the SH2 domain-containing tyrosine phosphatase SHPTP1

21 January 2018

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Negative regulation of the JAK/STAT pathway

21 January 2018

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The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

21 January 2018

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Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1.

21 January 2018

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SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine.

21 January 2018

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SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality

21 January 2018

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SOCS3 is essential in the regulation of fetal liver erythropoiesis

21 January 2018

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Specific inhibition of Stat3 signal transduction by PIAS3

21 January 2018

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Inhibition of Stat1-mediated gene activation by PIAS1

21 January 2018

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Localization of a target region of allelic loss to a 1-cM interval on chromosome 16p.13.13 in hepatocellular carcinoma.

21 January 2018

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Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

21 January 2018

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Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

21 January 2018

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Essential role of Stat6 in IL-4 signalling

21 January 2018

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Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

21 January 2018

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Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

21 January 2018

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Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

21 January 2018

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Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice

21 January 2018

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Loss of STAT1 expression confers resistance to IFN-gamma-induced apoptosis in ME180 cells

21 January 2018

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Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma

21 January 2018

1 reference

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Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis

21 January 2018

1 reference

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Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases

21 January 2018

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Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism

21 January 2018

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FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway

21 January 2018

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Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I.

21 January 2018

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Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesis

21 January 2018

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Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation

21 January 2018

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STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells

21 January 2018

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Stat5a is mandatory for adult mammary gland development and lactogenesis.

21 January 2018

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Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses

21 January 2018

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Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

21 January 2018

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Stat5 activation is uniquely associated with cytokine signaling in peripheral T cells

21 January 2018

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Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells

21 January 2018

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Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction

21 January 2018

1 reference

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Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor- mediated cell growth In vitro

21 January 2018

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Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

21 January 2018

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Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo

21 January 2018

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Stat3 activation is required for cellular transformation by v-src

21 January 2018

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Stat3 activation by Src induces specific gene regulation and is required for cell transformation

21 January 2018

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21 January 2018

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Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway.

21 January 2018

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Dual control of neurite outgrowth by STAT3 and MAP kinase in PC12 cells stimulated with interleukin-6.

21 January 2018

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STAT3 orchestrates contradictory signals in cytokine-induced G1 to S cell-cycle transition

21 January 2018

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Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis

21 January 2018

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STAT3 activation is a critical step in gp130-mediated terminal differentiation and growth arrest of a myeloid cell line

21 January 2018

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IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathways

21 January 2018

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Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3.

21 January 2018

1 reference

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Regulation of c-fos expression in transgenic mice requires multiple interdependent transcription control elements

21 January 2018

1 reference

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10.1002/1521-1878(200102)23:2<161::AID-BIES1023>3.0.CO;2-0

21 January 2018

Identifiers

DOI

1 reference

31 July 2017

1 reference

PubMed ID

11169589