Brain phenotype of transgenic mice overexpressing cystathionine β-synthase (Q34130338)

31 July 2017

Brain phenotype of transgenic mice overexpressing cystathionine β-synthase (English)

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31 July 2017

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Guido Vacano

11

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author name string

Vinciane Régnier

1

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31 July 2017

Jean-Marie Billard

2

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31 July 2017

Sapna Gupta

3

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31 July 2017

Brigitte Potier

4

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31 July 2017

Stéphanie Woerner

5

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31 July 2017

Evelyne Paly

6

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31 July 2017

Aurélie Ledru

7

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31 July 2017

Sabrina David

8

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31 July 2017

Sabrina Luilier

9

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31 July 2017

Jean-Charles Bizot

10

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31 July 2017

Jan P Kraus

12

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31 July 2017

David Patterson

13

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31 July 2017

Warren D Kruger

14

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31 July 2017

Jean M Delabar

15

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31 July 2017

Jaqueline London

16

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31 July 2017

language of work or name

English

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publication date

12 January 2012

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31 July 2017

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31 July 2017

7

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31 July 2017

1

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31 July 2017

e29056

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Creative Commons Attribution 4.0 International

31 July 2017

start time

12 January 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Impairment of methyl cycle affects mitochondrial methyl availability and glutathione level in Down's syndrome

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Mouse models of cognitive disabilities in trisomy 21 (Down syndrome).

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Effects of individual segmental trisomies of human chromosome 21 syntenic regions on hippocampal long-term potentiation and cognitive behaviors in mice.

5 July 2018

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Role of taurine in the central nervous system

5 July 2018

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A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions

5 July 2018

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Communication breaks-Down: from neurodevelopment defects to cognitive disabilities in Down syndrome

5 July 2018

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Hydrogen sulfide as a gasotransmitter

5 July 2018

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Molecular basis of pharmacotherapies for cognition in Down syndrome

5 July 2018

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A new mouse model for the trisomy of the Abcg1-U2af1 region reveals the complexity of the combinatorial genetic code of down syndrome

5 July 2018

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Aneuploidy: from a physiological mechanism of variance to Down syndrome

5 July 2018

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The undertow of sulfur metabolism on glutamatergic neurotransmission

5 July 2018

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Synaptic plasticity: multiple forms, functions, and mechanisms

5 July 2018

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Classification of human chromosome 21 gene-expression variations in Down syndrome: impact on disease phenotypes

5 July 2018

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Altered expression of mitochondrial and extracellular matrix genes in the heart of human fetuses with chromosome 21 trisomy

5 July 2018

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Natural gene-expression variation in Down syndrome modulates the outcome of gene-dosage imbalance

5 July 2018

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Plasma amino acids and neopterin in healthy persons with Down's syndrome

5 July 2018

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Hippocampal place cells, context, and episodic memory

5 July 2018

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Motor development and neuropsychological patterns in persons with Down syndrome

5 July 2018

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Primary and secondary transcriptional effects in the developing human Down syndrome brain and heart

5 July 2018

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Cystathionine beta-synthase, a key enzyme for homocysteine metabolism, is preferentially expressed in the radial glia/astrocyte lineage of developing mouse CNS

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257219

Redox regulation and reaction mechanism of human cystathionine-beta-synthase: a PLP-dependent hemesensor protein

5 July 2018

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Production of the neuromodulator H2S by cystathionine beta-synthase via the condensation of cysteine and homocysteine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257219

A chromosome 21 critical region does not cause specific Down syndrome phenotypes.

5 July 2018

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Sulfur amino acid metabolism: pathways for production and removal of homocysteine and cysteine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257219

Role of taurine uptake on the induction of long-term synaptic potentiation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257219

Glutathione metabolism and its implications for health

5 July 2018

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Long-Term Potentiation and Memory

5 July 2018

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5 July 2018

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The neuropsychology of Down syndrome: evidence for hippocampal dysfunction

5 July 2018

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New life in an old idea: the synaptic plasticity and memory hypothesis revisited

5 July 2018

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Role of S-adenosyl-L-methionine in the treatment of depression: a review of the evidence

5 July 2018

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

5 July 2018

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The LTP Program: a data acquisition program for on-line analysis of long-term potentiation and other synaptic events

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257219

Homocysteine metabolism in children with Down syndrome: in vitro modulation

5 July 2018

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Metabolism and functions of glutathione in brain.

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257219

Behavioral phenotyping of transgenic and knockout mice: experimental design and evaluation of general health, sensory functions, motor abilities, and specific behavioral tests

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257219

Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257219

Ts1Cje, a partial trisomy 16 mouse model for Down syndrome, exhibits learning and behavioral abnormalities

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257219

Identification and tissue distribution of human cystathionine beta-synthase mRNA isoforms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257219

Role of ventral hippocampus in acquisition, consolidation and retrieval of rat's passive avoidance response memory trace.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257219

Sequential role of hippocampus and amygdala, entorhinal cortex and parietal cortex in formation and retrieval of memory for inhibitory avoidance in rats.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257219

A mouse model for Down syndrome exhibits learning and behaviour deficits.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257219

Comparison of accelerod and rotarod sensitivity in detecting ethanol- and acrylamide-induced performance decrement in rats: review of experimental considerations of rotating rod systems.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257219

Studies of cystathionine synthase of rat liver: Dissociation into two components by sodium dodecyl sulfate disc electrophoresis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257219

Protocols to establish genotype-phenotype correlations in Down syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257219

Gene expression profiling in the adult Down syndrome brain.

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029056

Genetic dissection of region associated with behavioral abnormalities in mouse models for Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029056

Cystathionine beta-synthase is enriched in the brains of Down's patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029056

Expression of the cystathionine beta synthase (CBS) gene during mouse development and immunolocalization in adult brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029056

A functional transsulfuration pathway in the brain links to glutathione homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029056

Modulation of cystathionine beta-synthase level regulates total serum homocysteine in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029056

Abnormal lipid metabolism in cystathionine beta-synthase-deficient mice, an animal model for hyperhomocysteinemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029056

Rotorod sensorimotor learning in cerebellar mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029056

Sensorimotor learning in three cerebellar mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029056

Perturbations in homocysteine-linked redox homeostasis in a murine model for hyperhomocysteinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029056

Synaptic plasticity is impaired in rats with a low glutathione content.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029056

S-adenosyl-L-methionine improves impaired hippocampal long-term potentiation and water maze performance induced by developmental lead exposure in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029056

A simple polymerase chain reaction assay for genotyping the retinal degeneration mutation (Pdeb(rd1)) in FVB/N-derived transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029056

A behavioural characterisation of the FVB/N mouse strain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029056

NMDA receptor activation in the aged rat hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029056

Real-time quantitative PCR-based system for determining transgene copy number in transgenic animals.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257219

The possible role of hydrogen sulfide as an endogenous neuromodulator.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257219

Transsulfuration in mammals. Microassays and tissue distributions of three enzymes of the pathway.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257219

Differential involvement of the dorsal hippocampus in passive avoidance in C57bl/6J and DBA/2J mice

28 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029056

Biosynthesis of human cystathionine beta-synthase in cultured fibroblasts

21 January 2018

1 reference

12 December 2020

Cystathionine beta-synthase (human)

1 reference

12 December 2020

The production of transgenic mice expressing human cystathionine beta-synthase to study Down syndrome

1 reference

12 December 2020

Studies on cystathionine synthase of rat liver properties of the highly purified enzyme

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0029056

Identifiers

DOI

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31 July 2017

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31 July 2017

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