53BP1 cooperates with p53 and functions as a haploinsufficient tumor suppressor in mice (Q34124199)

31 July 2017

53BP1 cooperates with p53 and functions as a haploinsufficient tumor suppressor in mice (English)

1 reference

31 July 2017

0 references

5

Julian R Molina

1 reference

31 July 2017

Irene M Ward

1

1 reference

31 July 2017

Simone Difilippantonio

2

1 reference

31 July 2017

Kay Minn

3

1 reference

31 July 2017

Melissa D Mueller

4

1 reference

31 July 2017

Xiaochun Yu

6

1 reference

31 July 2017

Craig S Frisk

7

1 reference

31 July 2017

Thomas Ried

8

1 reference

31 July 2017

Andre Nussenzweig

9

1 reference

31 July 2017

Junjie Chen

10

1 reference

31 July 2017

language of work or name

English

0 references

publication date

1 November 2005

1 reference

Molecular and Cellular Biology

31 July 2017

1 reference

31 July 2017

25

1 reference

31 July 2017

10079-10086

1 reference

31 July 2017

22

1 reference

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

Deficiency in SNM1 abolishes an early mitotic checkpoint induced by spindle stress

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

53BP1 is required for class switch recombination

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

S-phase checkpoint genes safeguard high-fidelity sister chromatid cohesion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

H2AX haploinsufficiency modifies genomic stability and tumor susceptibility

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

Accumulation of Checkpoint Protein 53BP1 at DNA Breaks Involves Its Binding to Phosphorylated Histone H2AX

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

53BP1, a mediator of the DNA damage checkpoint

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

Loss of p53 and centrosome hyperamplification.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

Dissecting p53 tumor suppressor functions in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

Kinetochore localisation of the DNA damage response component 53BP1 during mitosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

Negative cell cycle regulation and DNA damage-inducible phosphorylation of the BRCT protein 53BP1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

Megabase chromatin domains involved in DNA double-strand breaks in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

Critical role for Atm in suppressing V(D)J recombination-driven thymic lymphoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

Stimulation of p53-mediated transcriptional activation by the p53-binding proteins, 53BP1 and 53BP2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

No requirement for V(D)J recombination in p53-deficient thymic lymphoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

Mutations of mitotic checkpoint genes in human cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

Multicolour spectral karyotyping of mouse chromosomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

BRCA1 protein products ... Functional motifs...

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

Two cellular proteins that bind to wild-type but not mutant p53

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280262

Histone H2AX: a dosage-dependent suppressor of oncogenic translocations and tumors

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16260621

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The Tudor tandem of 53BP1: a new structural motif involved in DNA and RG-rich peptide binding

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16260621

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining genomic stability

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16260621

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.25.22.10079-10086.2005

1 reference

31 July 2017

1 reference

31 July 2017

1 reference