Pax3 stimulates p53 ubiquitination and degradation independent of transcription (Q34117536)

31 July 2017

Pax3 stimulates p53 ubiquitination and degradation independent of transcription (English)

1 reference

31 July 2017

protein ubiquitination

1 reference

Mary R Loeken

3

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author name string

Xiao Dan Wang

series ordinal

1

1 reference

PubMed ID

22216266

31 July 2017

Sarah C Morgan

series ordinal

2

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PubMed ID

22216266

31 July 2017

language of work or name

English

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publication date

28 December 2011

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31 July 2017

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31 July 2017

6

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31 July 2017

12

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31 July 2017

e29379

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Creative Commons Attribution 4.0 International

31 July 2017

start time

28 December 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Pax3 is essential for normal cardiac neural crest morphogenesis but is not required during migration nor outflow tract septation

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Suppression of induced pluripotent stem cell generation by the p53-p21 pathway

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Immortalization eliminates a roadblock during cellular reprogramming into iPS cells

5 July 2018

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A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

5 July 2018

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Linking the p53 tumour suppressor pathway to somatic cell reprogramming

5 July 2018

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Cardiac outflow tract septation failure in Pax3-deficient embryos is due to p53-dependent regulation of migrating cardiac neural crest

5 July 2018

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Dissection of the functional interaction between p53 and the embryonic proto-oncoprotein PAX3.

5 July 2018

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A PANorama of PAX genes in cancer and development

5 July 2018

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Temporally regulated neural crest transcription factors distinguish neuroectodermal tumors of varying malignancy and differentiation.

5 July 2018

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p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression

5 July 2018

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A dynamic switch in the replication timing of key regulator genes in embryonic stem cells upon neural induction.

5 July 2018

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The transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signaling in vivo.

5 July 2018

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The expression of the developmentally regulated proto-oncogene Pax-3 is modulated by N-Myc

5 July 2018

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Rescue of neural tube defects in Pax-3-deficient embryos by p53 loss of function: implications for Pax-3- dependent development and tumorigenesis

5 July 2018

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Microarray analysis detects novel Pax3 downstream target genes

5 July 2018

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Homeodomain proteins Mox1 and Mox2 associate with Pax1 and Pax3 transcription factors

5 July 2018

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Dual inactivation of RB and p53 pathways in RAS-induced melanomas

5 July 2018

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PAX3 is expressed in human melanomas and contributes to tumor cell survival

5 July 2018

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Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells.

5 July 2018

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5 July 2018

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Expression of genes for microphthalmia isoforms, Pax3 and MSG1, in human melanomas

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247257

Msx1 antagonizes the myogenic activity of Pax3 in migrating limb muscle precursors.

5 July 2018

1 reference

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The highly conserved beta-hairpin of the paired DNA-binding domain is required for assembly of Pax-Ets ternary complexes

5 July 2018

1 reference

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Identification of a new binding motif for the paired domain of Pax-3 and unusual characteristics of spacing of bipartite recognition elements on binding and transcription activation

5 July 2018

1 reference

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Epistatic relationship between Waardenburg syndrome genes MITF and PAX3

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247257

Interaction of the pRB-family proteins with factors containing paired-like homeodomains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247257

Gender and androgen treatment influence the expression of proto-oncogenes and apoptotic factors in lacrimal and salivary tissues of MRL/lpr mice.

5 July 2018

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5 July 2018

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Neural tube defects in embryos of diabetic mice: role of the Pax-3 gene and apoptosis.

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247257

Expression of PAX3 in Ewing's sarcoma family of tumors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247257

Ectopic Pax-3 activates MyoD and Myf-5 expression in embryonic mesoderm and neural tissue

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247257

Redefining the genetic hierarchies controlling skeletal myogenesis: Pax-3 and Myf-5 act upstream of MyoD.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247257

Pax3 modulates expression of the c-Met receptor during limb muscle development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247257

Loss of p53 function through PAX-mediated transcriptional repression.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247257

A mutation within intron 3 of the Pax-3 gene produces aberrantly spliced mRNA transcripts in the splotch (Sp) mouse mutant

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247257

The oncogenic potential of Pax genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247257

Pax-3-DNA interaction: flexibility in the DNA binding and induction of DNA conformational changes by paired domains.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247257

Molecular basis of splotch and Waardenburg Pax-3 mutations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247257

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247257

Pax-3 contains domains for transcription activation and transcription inhibition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247257

Identification of DNA recognition sequences for the Pax3 paired domain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247257

Pax-3, a novel murine DNA binding protein expressed during early neurogenesis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247257

CNS stem cells express a new class of intermediate filament protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247257

Regulation of murine TGFbeta2 by Pax3 during early embryonic development.

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029379

Reduced expression of pax-3 is associated with overexpression of cdc46 in the mouse embryo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029379

Identification of Dep-1, a new gene regulated by the transcription factor Pax-3, as a marker for altered embryonic gene expression during diabetic pregnancy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029379

Pax3 regulates Wnt1 expression via a conserved binding site in the 5' proximal promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029379

Oxidant regulation of gene expression and neural tube development: Insights gained from diabetic pregnancy on molecular causes of neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029379

AMP-activated protein kinase (AMPK) is activated in muscle of subjects with type 2 diabetes during exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029379

Acetylation of p53 inhibits its ubiquitination by Mdm2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029379

Msx2 is an immediate downstream effector of Pax3 in the development of the murine cardiac neural crest.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247257

Migration of cardiac neural crest cells in Splotch embryos.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247257

Apoptosis during bone-like tissue development in vitro.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247257

Pax3 and Regulation of the Melanocyte-specific Tyrosinase-related Protein-1 Promoter

28 October 2018

1 reference

12 December 2020

Analysis of the Pax-3 gene in the mouse mutant splotch

1 reference

12 December 2020

Absence of p53 gene mutations in primary neuroblastomas

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12 December 2020

Pax-3 is required for the development of limb muscles: a possible role for the migration of dermomyotomal muscle progenitor cells

1 reference

12 December 2020

Investigation of downstream target genes of PAX3c, PAX3e and PAX3g isoforms in melanocytes by microarray analysis

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0029379

Identifiers

DOI

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference

PubMed ID

22216266