Pax3 is essential for normal cardiac neural crest morphogenesis but is not required during migration nor outflow tract septation (Q35127152)

6 August 2017

Pax3 is essential for normal cardiac neural crest morphogenesis but is not required during migration nor outflow tract septation (English)

1 reference

6 August 2017

1 reference

Michael Olaopa

1

1 reference

6 August 2017

Hong-ming Zhou

2

1 reference

6 August 2017

Paige Snider

3

1 reference

6 August 2017

Jian Wang

4

1 reference

6 August 2017

Robert J Schwartz

5

1 reference

6 August 2017

Anne M Moon

6

1 reference

6 August 2017

Simon J Conway

7

1 reference

6 August 2017

language of work or name

English

0 references

publication date

12 May 2011

1 reference

6 August 2017

Developmental Biology

1 reference

6 August 2017

356

1 reference

6 August 2017

2

1 reference

6 August 2017

308-322

1 reference

describes a project that uses

6 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3143301/fullTextXML

inferred from PubMed Central ID database lookup

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Phosphatase-dependent and -independent functions of Shp2 in neural crest cells underlie LEOPARD syndrome pathogenesis

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13 July 2018

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Retinoic acid regulates differentiation of the secondary heart field and TGFbeta-mediated outflow tract septation

13 July 2018

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22q11 deletion syndrome: a role for TBX1 in pharyngeal and cardiovascular development

13 July 2018

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Distinct enhancers at the Pax3 locus can function redundantly to regulate neural tube and neural crest expressions

13 July 2018

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Apoptosis is not required for mammalian neural tube closure.

13 July 2018

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Generation of Smad7(-Cre) recombinase mice: A useful tool for the study of epithelial-mesenchymal transformation within the embryonic heart

13 July 2018

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Treacher Collins syndrome: etiology, pathogenesis and prevention

13 July 2018

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Evolution of the neural crest viewed from a gene regulatory perspective

13 July 2018

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Pbx1 functions in distinct regulatory networks to pattern the great arteries and cardiac outflow tract

13 July 2018

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Oxidative stress during diabetic pregnancy disrupts cardiac neural crest migration and causes outflow tract defects

13 July 2018

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Generation and characterization of Csrp1 enhancer-driven tissue-restricted Cre-recombinase mice

13 July 2018

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Periostin is required for maturation and extracellular matrix stabilization of noncardiomyocyte lineages of the heart

13 July 2018

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Lineage-specific responses to reduced embryonic Pax3 expression levels

13 July 2018

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Identification and characterization of a novel Schwann and outflow tract endocardial cushion lineage-restricted periostin enhancer.

13 July 2018

1 reference

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Model systems for the study of heart development and disease. Cardiac neural crest and conotruncal malformations

13 July 2018

1 reference

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Development of the neural crest: achieving specificity in regulatory pathways

13 July 2018

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The neurofibromin GAP-related domain rescues endothelial but not neural crest development in Nf1 mice

13 July 2018

1 reference

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Distinct cardiac malformations caused by absence of connexin 43 in the neural crest and in the non-crest neural tube

13 July 2018

1 reference

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Cardiovascular malformations with normal smooth muscle differentiation in neural crest-specific type II TGFbeta receptor (Tgfbr2) mutant mice

13 July 2018

1 reference

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In vivo genetic ablation by Cre-mediated expression of diphtheria toxin fragment A.

13 July 2018

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13 July 2018

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Recent advances in cardiac development with therapeutic implications for adult cardiovascular disease

13 July 2018

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Pax3 functions at a nodal point in melanocyte stem cell differentiation

13 July 2018

1 reference

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Gene-regulatory interactions in neural crest evolution and development

13 July 2018

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BMP receptor IA is required in mammalian neural crest cells for development of the cardiac outflow tract and ventricular myocardium

13 July 2018

1 reference

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Identification of minimal enhancer elements sufficient for Pax3 expression in neural crest and implication of Tead2 as a regulator of Pax3

13 July 2018

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Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/- mast cells

13 July 2018

1 reference

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Ablation of specific expression domains reveals discrete functions of ectoderm- and endoderm-derived FGF8 during cardiovascular and pharyngeal development

13 July 2018

1 reference

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Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction

13 July 2018

1 reference

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Neural crest and cardiovascular development: a 20-year perspective

13 July 2018

1 reference

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The homeobox gene Lbx1 specifies a subpopulation of cardiac neural crest necessary for normal heart development

13 July 2018

1 reference

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What cardiovascular defect does my prenatal mouse mutant have, and why?

13 July 2018

1 reference

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Pax3-FKHR knock-in mice show developmental aberrations but do not develop tumors

13 July 2018

1 reference

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Requirement for AP-2alpha in cardiac outflow tract morphogenesis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Pax3 acts cell autonomously in the neural tube and somites by controlling cell surface properties

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Conditional vascular cell adhesion molecule 1 deletion in mice: impaired lymphocyte migration to bone marrow

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Inhibition of noggin expression in the dorsal neural tube by somitogenesis: a mechanism for coordinating the timing of neural crest emigration.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Decreased neural crest stem cell expansion is responsible for the conotruncal heart defects within the splotch (Sp(2H))/Pax3 mouse mutant

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Fate of the mammalian cardiac neural crest

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Transgenic rescue of congenital heart disease and spina bifida in Splotch mice.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Generalized lacZ expression with the ROSA26 Cre reporter strain

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Over-expression of the chondroitin sulphate proteoglycan versican is associated with defective neural crest migration in the Pax3 mutant mouse (splotch).

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Wnt signalling required for expansion of neural crest and CNS progenitors.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Neural crest is involved in development of abnormal myocardial function.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Cx43 gap junction gene expression and gap junctional communication in mouse neural crest cells.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Transcription factor AP-2 essential for cranial closure and craniofacial development

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Patterning of the vertebrate neural crest.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Local sources of retinoic acid coincide with retinoid-mediated transgene activity during embryonic development

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Neural crest cells contribute to normal aorticopulmonary septation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

The anatomy of common aorticopulmonary trunk (truncus arteriosus communis) and its embryologic implications. A study of 57 necropsy cases

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Pax-3, a novel murine DNA binding protein expressed during early neurogenesis.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Neural tube defects without neural crest defects in Splotch mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Dual role for neural crest cells during outflow tract septation in the neural crest-deficient mutant Splotch(2H).

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Pulmonary atresia or persistent truncus arteriosus: is it important to make the distinction and how do we do it?

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Haemodynamics determined by a genetic programme govern asymmetric development of the aortic arch.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Cardiovascular development and the colonizing cardiac neural crest lineage.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Independent requirements for Hedgehog signaling by both the anterior heart field and neural crest cells for outflow tract development.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Rotation of the myocardial wall of the outflow tract is implicated in the normal positioning of the great arteries.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Cardiac neural crest is necessary for normal addition of the myocardium to the arterial pole from the secondary heart field.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Developmental consequences of abnormal folate transport during murine heart morphogenesis.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Cardiac neural crest of the mouse embryo: axial level of origin, migratory pathway and cell autonomy of the splotch (Sp2H) mutant effect

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Msx2 is an immediate downstream effector of Pax3 in the development of the murine cardiac neural crest.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Embryonic expression of an Nkx2-5/Cre gene using ROSA26 reporter mice.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Migration of cardiac neural crest cells in Splotch embryos.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Sox4-deficiency syndrome in mice is an animal model for common trunk.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Role of cardiac neural crest cells in cardiovascular development

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Analysis of neural crest cell migration in Splotch mice using a neural crest-specific LacZ reporter.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Expression of Pax-3 is initiated in the early neural plate by posteriorizing signals produced by the organizer and by posterior non-axial mesoderm.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Abnormal patterning of the aortic arch arteries does not evoke cardiac malformations.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Interaction between splotch (Sp) and curly tail (ct) mouse mutants in the embryonic development of neural tube defects.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Experimental analysis of the migration and differentiation of neuroblasts of the autonomic nervous system and of neurectodermal mesenchymal derivatives, using a biological cell marking technique.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143301

Insertion of Cre into the Pax3 locus creates a new allele of Splotch and identifies unexpected Pax3 derivatives

27 September 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2011.05.583

Generation of a conditional loxP allele of the Pax3 transcription factor that enables selective deletion of the homeodomain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2011.05.583

The role of Pax3 and Pax7 in development and cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2011.05.583

Temporal-spatial ablation of neural crest in the mouse results in cardiovascular defects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2011.05.583

Another key role for the cardiac neural crest in heart development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2011.05.583

Developmental biology: the power of blood

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2011.05.583

The del22q11.2 candidate gene Tbx1 controls regional outflow tract identity and coronary artery patterning

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2011.05.583

Development. Riding the crest of the Wnt signaling wave

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2011.05.583

Cardiac neural crest is essential for the persistence rather than the formation of an arch artery

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2011.05.583

A novel role for cardiac neural crest in heart development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2011.05.583

A novel transgenic technique that allows specific marking of the neural crest cell lineage in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2011.05.583

Pax3 is required for cardiac neural crest migration in the mouse: evidence from the splotch (Sp2H) mutant

7 January 2021

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21600894

12 December 2020

inferred from PubMed ID database lookup

[Waardenburg syndrome. Report of a familial case]

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21600894

12 December 2020

inferred from PubMed ID database lookup

[Waardenburg's syndrome and severe cyanotic cardiopathy]

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21600894

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.YDBIO.2011.05.583

1 reference

6 August 2017

1 reference

6 August 2017

1 reference