Formation of apoptosome is initiated by cytochrome c-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1. (Q34098735)

31 July 2017

Formation of apoptosome is initiated by cytochrome c-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1. (English)

1 reference

31 July 2017

1 reference

Hyun-Eui Kim

1

1 reference

31 July 2017

Fenghe Du

series ordinal

2

1 reference

31 July 2017

Min Fang

series ordinal

3

1 reference

31 July 2017

Xiaodong Wang

series ordinal

4

1 reference

31 July 2017

language of work or name

English

0 references

publication date

26 October 2005

1 reference

Proceedings of the National Academy of Sciences of the United States of America

31 July 2017

1 reference

31 July 2017

102

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31 July 2017

17545-17550

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31 July 2017

49

1 reference

describes a project that uses

31 July 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1266161/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Drosophila caspase DRONC is required for specific developmental cell death pathways and stress-induced apoptosis

5 July 2018

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Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway

5 July 2018

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The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

5 July 2018

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5 July 2018

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Nods: a family of cytosolic proteins that regulate the host response to pathogens

5 July 2018

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Control of the cell death pathway by Dapaf-1, a Drosophila Apaf-1/CED-4-related caspase activator

5 July 2018

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HAC-1, a Drosophila homolog of APAF-1 and CED-4 functions in developmental and radiation-induced apoptosis

5 July 2018

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Caspase-9 and APAF-1 form an active holoenzyme

5 July 2018

1 reference

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Dark is a Drosophila homologue of Apaf-1/CED-4 and functions in an evolutionarily conserved death pathway

5 July 2018

1 reference

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Regulation of apoptotic protease activating factor-1 oligomerization and apoptosis by the WD-40 repeat region

5 July 2018

1 reference

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An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

5 July 2018

1 reference

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5 July 2018

Caspases: enemies within

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Differential requirement for caspase 9 in apoptotic pathways in vivo.

5 July 2018

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Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

5 July 2018

1 reference

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Induction of an apoptotic program in cell-free extracts by 2-chloro-2'-deoxyadenosine 5'-triphosphate and cytochrome c

5 July 2018

1 reference

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Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

5 July 2018

1 reference

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

5 July 2018

1 reference

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Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

5 July 2018

1 reference

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Intracellular ATP levels determine cell death fate by apoptosis or necrosis.

5 July 2018

1 reference

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Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1266161

Human ICE/CED-3 protease nomenclature

5 July 2018

1 reference

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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

5 July 2018

1 reference

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The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

5 July 2018

1 reference

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Cell death: the significance of apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1266161

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1266161

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1266161

The Caenorhabditis elegans cell death gene ced-4 encodes a novel protein and is expressed during the period of extensive programmed cell death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1266161

The apical caspase dronc governs programmed and unprogrammed cell death in Drosophila

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0507900102

Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0507900102

Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16251271

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cytochrome c promotes caspase-9 activation by inducing nucleotide binding to Apaf-1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16251271

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0507900102

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference