Anti-inflammatory activity and neutrophil reductions mediated by the JAK1/JAK3 inhibitor, CP-690,550, in rat adjuvant-induced arthritis (Q34084020)

30 July 2017

Anti-inflammatory activity and neutrophil reductions mediated by the JAK1/JAK3 inhibitor, CP-690,550, in rat adjuvant-induced arthritis (English)

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30 July 2017

Debra M Meyer

1

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30 July 2017

Michael I Jesson

2

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30 July 2017

Xiong Li

3

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30 July 2017

Mollisa M Elrick

4

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30 July 2017

Christie L Funckes-Shippy

5

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30 July 2017

James D Warner

6

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30 July 2017

Cindy J Gross

7

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30 July 2017

Martin E Dowty

8

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30 July 2017

Shashi K Ramaiah

9

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30 July 2017

Jeffrey L Hirsch

10

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30 July 2017

Matthew J Saabye

11

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30 July 2017

Jennifer L Barks

12

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30 July 2017

Nandini Kishore

13

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30 July 2017

Dale L Morris

14

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30 July 2017

language of work or name

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11 August 2010

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30 July 2017

Journal of Inflammation

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30 July 2017

7

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30 July 2017

41

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https://scigraph.springernature.com/pub.10.1186/1476-9255-7-41

30 July 2017

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The JAK kinase inhibitor CP-690,550 suppresses the growth of human polycythemia vera cells carrying the JAK2V617F mutation

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Cartilage preservation by inhibition of Janus kinase 3 in two rodent models of rheumatoid arthritis

28 July 2018

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Expression and regulation of CCL18 in synovial fluid neutrophils of patients with rheumatoid arthritis

28 July 2018

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28 July 2018

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28 July 2018

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Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses

28 July 2018

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Granulocyte-macrophage colony-stimulating factor stimulates JAK2 signaling pathway and rapidly activates p93fes, STAT1 p91, and STAT3 p92 in polymorphonuclear leukocytes

28 July 2018

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Implication of granulocyte-macrophage colony-stimulating factor induced neutrophil gelatinase-associated lipocalin in pathogenesis of rheumatoid arthritis revealed by proteome analysis

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A semi-mechanistic model of CP-690,550-induced reduction in neutrophil counts in patients with rheumatoid arthritis.

28 October 2018

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IL-17 and Th17 cells in human inflammatory diseases

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Effect of CP-690,550, an orally active janus kinase inhibitor, on renal function in healthy adult volunteers

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28 October 2018

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The JAK3 inhibitor CP-690550 selectively reduces NK and CD8+ cell numbers in cynomolgus monkey blood following chronic oral dosing

28 October 2018

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The novel JAK-3 inhibitor CP-690550 is a potent immunosuppressive agent in various murine models

28 October 2018

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28 October 2018

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28 October 2018

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28 October 2018

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28 October 2018

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28 October 2018

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Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis

28 October 2018

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28 October 2018

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28 October 2018

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28 October 2018

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12 December 2020

Treatment of established adjuvant arthritis in rats with monoclonal antibody to CD18 and very late activation antigen-4 integrins suppresses neutrophil and T-lymphocyte migration to the joints and improves clinical disease

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12 December 2020

Selective functional inhibition of JAK-3 is sufficient for efficacy in collagen-induced arthritis in mice

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12 December 2020

Anti-neutrophil monoclonal antibody therapy inhibits the development of adjuvant arthritis

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12 December 2020

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12 December 2020

Neutrophil apoptosis in rheumatoid arthritis is regulated by local oxygen tensions within joints

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12 December 2020

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12 December 2020

Stopping the traffic: a route to arthritis therapy

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12 December 2020

Neutrophils and adjuvant arthritis

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12 December 2020

Identifiers

DOI

10.1186/1476-9255-7-41

1 reference

Dimensions Publication ID

30 July 2017

0 references

1 reference

30 July 2017

1 reference