Signaling takes shape in the immune system (Q34073408)

30 July 2017

title

Signaling takes shape in the immune system (English)

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30 July 2017

Dustin ML

1

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30 July 2017

Chan AC

series ordinal

2

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30 July 2017

publication date

1 October 2000

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30 July 2017

language of work or name

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30 July 2017

volume

103

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30 July 2017

issue

2

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30 July 2017

page(s)

283-294

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publication type of scholarly work

30 July 2017

review article

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Concentration of MHC class II molecules in lipid rafts facilitates antigen presentation

cites work

1 reference

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7 January 2021

Thermodynamics of T cell receptor binding to peptide-MHC: evidence for a general mechanism of molecular scanning

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7 January 2021

Two distinct mechanisms for redistribution of lymphocyte surface macromolecules. I. Relationship to cytoplasmic myosin

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7 January 2021

Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation

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7 January 2021

Cutting edge: hierarchy of chemokine receptor and TCR signals regulating T cell migration and proliferation

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7 January 2021

Structure and function of sphingolipid- and cholesterol-rich membrane rafts

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade

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7 January 2021

Protein tyrosine kinases in thymocyte development

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Requirement of the SH3 and SH2 domains for the inhibitory function of tyrosine protein kinase p50csk in T lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF-kappaB pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

The GTPase rho controls a p53-dependent survival checkpoint during thymopoiesis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Orchestrated information transfer underlying leukocyte endothelial interactions.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Activation of mechanical responses in leukocytes

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

SH2 domains exhibit high-affinity binding to tyrosine-phosphorylated peptides yet also exhibit rapid dissociation and exchange

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Ligand binding regulates the directed movement of beta1 integrins on fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Actin-based motility of vaccinia virus mimics receptor tyrosine kinase signalling.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

The immunological synapse: a molecular machine controlling T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Antigen presentation in extracellular matrix: interactions of T cells with dendritic cells are dynamic, short lived, and sequential

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Lck regulates Vav activation of members of the Rho family of GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

A Drosophila homolog of the Rac- and Cdc42-activated serine/threonine kinase PAK is a potential focal adhesion and focal complex protein that colocalizes with dynamic actin structures

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Activation by Cdc42 and PIP(2) of Wiskott-Aldrich syndrome protein (WASp) stimulates actin nucleation by Arp2/3 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

The Duration of Antigenic Stimulation Determines the Fate of Naive and Effector T Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

In vivo detection of dendritic cell antigen presentation to CD4(+) T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

A supramolecular basis for CD45 tyrosine phosphatase regulation in sustained T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Differential clustering of CD4 and CD3zeta during T cell recognition

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Adhesion-activating phorbol ester increases the mobility of leukocyte integrin LFA-1 in cultured lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Polarized expression of cytokines in cell conjugates of helper T cells and splenic B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Activation of T cells by a tyrosine kinase activation domain in the cytoplasmic tail of CD3 epsilon.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Exclusion of CD45 from the T-cell receptor signaling area in antigen-stimulated T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Role of the Guanosine Triphosphatase Rac2 in T Helper 1 Cell Differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

The polarization defect of Wiskott-Aldrich syndrome macrophages is linked to dislocalization of the Arp2/3 complex.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Gads is a novel SH2 and SH3 domain-containing adaptor protein that binds to tyrosine-phosphorylated Shc

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Cytoskeletal Polarization of T Cells Is Regulated by an Immunoreceptor Tyrosine-based Activation Motif–dependent Mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Dual role of the actin cytoskeleton in regulating cell adhesion mediated by the integrin lymphocyte function-associated molecule-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Putting on the brakes: a negative regulatory function for Ena/VASP proteins in cell migration

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

RAC1/P38 MAPK signaling pathway controls beta1 integrin-induced interleukin-8 production in human natural killer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

PAK Kinases Are Directly Coupled to the PIX Family of Nucleotide Exchange Factors

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Dimerization-Induced Inhibition of Receptor Protein Tyrosine Phosphatase Function Through an Inhibitory Wedge

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Lipid-dependent Targeting of G Proteins into Rafts

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Three-dimensional segregation of supramolecular activation clusters in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Adapter proteins in lymphocyte antigen-receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Lymphocyte responses and cytokines

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Ligand-specific oligomerization of T-cell receptor molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

The protein tyrosine phosphatase SHP-1 regulates integrin-mediated adhesion of macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Exclusion of CD45 inhibits activity of p56lck associated with glycolipid-enriched membrane domains

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Phosphatidylinositol 4,5-bisphosphate induces actin-based movement of raft-enriched vesicles through WASP-Arp2/3.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Integrin-cytoskeletal interactions in migrating fibroblasts are dynamic, asymmetric, and regulated

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Polarization of chemoattractant receptor signaling during neutrophil chemotaxis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Critical role for cholesterol in Lyn-mediated tyrosine phosphorylation of FcepsilonRI and their association with detergent-resistant membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Wiskott-Aldrich Syndrome Protein-Deficient Mice Reveal a Role for WASP in T but Not B Cell Activation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Adhesion receptors of the immune system

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

CD28 affects the earliest signaling events generated by TCR engagement

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Transport of peptide-MHC class II complexes in developing dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Ligand-induced movement of lymphocyte membrane macromolecules. I. Analysis by immunofluorescence and ultrastructural radioautography

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Dynamic interactions of macrophages with T cells during antigen presentation.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Serial triggering of many T-cell receptors by a few peptide-MHC complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Directed actin polymerization is the driving force for epithelial cell-cell adhesion

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

A novel functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

T lymphocyte costimulation mediated by reorganization of membrane microdomains

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Mapping the sensitivity of T cells with an optical trap: polarity and minimal number of receptors for Ca(2+) signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Spatial control of actin polymerization during neutrophil chemotaxis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

A motif in the alphabeta T-cell receptor controls positive selection by modulating ERK activity

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Dependence of T cell antigen recognition on the dimensions of an accessory receptor-ligand complex

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

A receptor/cytoskeletal movement triggered by costimulation during T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Visualizing the dynamics of T cell activation: Intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Tec kinases: a family with multiple roles in immunity

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Non-CD28 costimulatory molecules present in T cell rafts induce T cell costimulation by enhancing the association of TCR with rafts

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900120-3

7 January 2021

10.1016/S0092-8674(00)00120-3

Identifiers

DOI

1 reference

30 July 2017

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