Expression of DNA polymerase {beta} cancer-associated variants in mouse cells results in cellular transformation (Q34063561)

30 July 2017

Expression of DNA polymerase {beta} cancer-associated variants in mouse cells results in cellular transformation (English)

1 reference

30 July 2017

1

Joann B Sweasy

1 reference

30 July 2017

Tieming Lang

2

1 reference

30 July 2017

Daniela Starcevic

3

1 reference

30 July 2017

Ka-Wai Sun

4

1 reference

30 July 2017

Char-Chang Lai

5

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30 July 2017

Daniel Dimaio

6

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30 July 2017

Shibani Dalal

7

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30 July 2017

language of work or name

English

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publication date

22 September 2005

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30 July 2017

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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30 July 2017

102

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30 July 2017

40

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30 July 2017

14350-14355

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describes a project that uses

30 July 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1242307/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Productive interaction between transmembrane mutants of the bovine papillomavirus E5 protein and the platelet-derived growth factor beta receptor.

5 July 2018

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Is there a link between DNA polymerase beta and cancer?

5 July 2018

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A DNA polymerase beta mutant from colon cancer cells induces mutations

5 July 2018

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Variants of DNA polymerase Beta extend mispaired DNA due to increased affinity for nucleotide substrate

5 July 2018

1 reference

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Deregulated DNA polymerase beta induces chromosome instability and tumorigenesis

5 July 2018

1 reference

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A DNA polymerase beta mutator mutant with reduced nucleotide discrimination and increased protein stability

5 July 2018

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Defective DNA repair genes in a primary culture of human renal cell carcinoma

5 July 2018

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The Tyr-265-to-Cys mutator mutant of DNA polymerase beta induces a mutator phenotype in mouse LN12 cells

5 July 2018

1 reference

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The Pol beta-14 dominant negative rat DNA polymerase beta mutator mutant commits errors during the gap-filling step of base excision repair in Saccharomyces cerevisiae.

5 July 2018

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A variant of DNA polymerase beta acts as a dominant negative mutant

5 July 2018

1 reference

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DNA polymerase beta: structure-fidelity relationship from Pre-steady-state kinetic analyses of all possible correct and incorrect base pairs for wild type and R283A mutant

5 July 2018

1 reference

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Crystal structures of human DNA polymerase beta complexed with DNA: implications for catalytic mechanism, processivity, and fidelity

5 July 2018

1 reference

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DNA polymerase beta: pre-steady-state kinetic analysis and roles of arginine-283 in catalysis and fidelity.

5 July 2018

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Self-contained, tetracycline-regulated retroviral vector system for gene delivery to mammalian cells

5 July 2018

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Instability and decay of the primary structure of DNA

5 July 2018

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The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

5 July 2018

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DNA polymerase beta gene mutation in human prostate cancer.

5 July 2018

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Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair

5 July 2018

1 reference

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Identification of mismatch repair genes and their role in the development of cancer

5 July 2018

1 reference

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DNA polymerase beta mutations in human colorectal cancer

5 July 2018

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Helper-independent transformation by unintegrated Harvey sarcoma virus DNA

5 July 2018

1 reference

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Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps.

5 July 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0505166102

Variant forms of DNA polymerase beta in primary lung carcinomas.

21 January 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0505166102

Enzyme-DNA interactions required for efficient nucleotide incorporation and discrimination in human DNA polymerase beta.

21 January 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0505166102

Identification of 127 amino acid substitution variants in screening 37 DNA repair genes in humans.

21 January 2018

1 reference

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Alternative splicing of DNA polymerase beta mRNA is not tumor-specific

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16179390

12 December 2020

inferred from PubMed ID database lookup

The mutator form of polymerase beta with amino acid substitution at tyrosine 265 in the hinge region displays an increase in both base substitution and frame shift errors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16179390

12 December 2020

inferred from PubMed ID database lookup

Y265H mutator mutant of DNA polymerase beta. Proper teometric alignment is critical for fidelity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16179390

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.0505166102

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference