Potential health impacts of excessive flavonoid intake (Q34062734)

30 July 2017

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title

Potential health impacts of excessive flavonoid intake (English)

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30 July 2017

C F Skibola

1

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PubMed ID

11035267

30 July 2017

M T Smith

series ordinal

2

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30 July 2017

1 August 2000

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Free Radical Biology and Medicine

30 July 2017

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30 July 2017

29

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30 July 2017

3-4

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30 July 2017

375-383

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Effects of flavonoids and vitamin C on oxidative DNA damage to human lymphocytes

30 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Antioxidant capacity and polyphenolic components of teas: implications for altering in vivo antioxidant status

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Inhibitory effect of green and black tea on tumor growth

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Site-specific DNA cleavage by mammalian DNA topoisomerase II induced by novel flavone and catechin derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Flavonoids as DNA topoisomerase antagonists and poisons: structure-activity relationships

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Quercetin induces recombinational mutations in cultured cells as detected by DNA fingerprinting

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Induction of sister-chromatid exchanges (SCE), polyploidy, and micronuclei by plant flavonoids in human lymphocyte cultures. A comparative study of 19 flavonoids

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Study on the mutagenic activity of 13 bioflavonoids with the Salmonella Ara test.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Lipid peroxidation and DNA damage induced by morin and naringenin in isolated rat liver nuclei.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Molecular mechanisms of oxygen radical carcinogenesis and mutagenesis: the role of DNA base damage

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Reduced oxygen species, mutation, induction and cancer initiation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in the Netherlands

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Tofu and soy drinks contain phytoestrogens

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Intake of potentially anticarcinogenic flavonoids and their determinants in adults in The Netherlands

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Dietary flavonoids and the risk of lung cancer and other malignant neoplasms.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Flavonoid intake and long-term risk of coronary heart disease and cancer in the seven countries study

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Relation between intake of flavonoids and risk for coronary heart disease in male health professionals

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Modulating effect of resveratrol and quercetin on oral cancer cell growth and proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Effects of naturally-occurring flavonoids and biflavonoids on epidermal cyclooxygenase and lipoxygenase from guinea-pigs

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Antiproliferative activity of flavonoids on several cancer cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

The sugar moiety is a major determinant of the absorption of dietary flavonoid glycosides in man

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Consumption of quercetin and kaempferol in free-living subjects eating a variety of diets.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Relative bioavailability of the antioxidant flavonoid quercetin from various foods in man

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Effects of theaflavins on N-nitrosomethylbenzylamine-induced esophageal tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Mechanisms of growth inhibition of human lung cancer cell line, PC-9, by tea polyphenols

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Effect of (-)-epigallocatechin gallate on leukemic blast cells from patients with acute myeloblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Polyphenolic flavanols as scavengers of aqueous phase radicals and as chain-breaking antioxidants

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

The antioxidant properties of theaflavins and their gallate esters--radical scavengers or metal chelators?

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Interactions between phytoestrogens and human sex steroid binding protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Regulation of sex hormone-binding globulin production by isoflavonoids and patterns of isoflavonoid conjugation in HepG2 cell cultures.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Estrogen-specific 17 beta-hydroxysteroid oxidoreductase type 1 (E.C. 1.1.1.62) as a possible target for the action of phytoestrogens

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Dietary estrogenic isoflavones are potent inhibitors of beta-hydroxysteroid dehydrogenase of P. testosteronii

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Genistein, daidzein, and their .beta.-glycoside conjugates: antitumor isoflavones in soybean foods from American and Asian diets

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Rapid HPLC analysis of dietary phytoestrogens from legumes and from human urine

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Effect of genistein on topoisomerase activity and on the growth of [Val 12]Ha-ras-transformed NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Effect of the protein tyrosine kinase inhibitor genistein on normal and leukaemic haemopoietic progenitor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Genistein-induced cell differentiation and protein-linked DNA strand breakage in human melanoma cells

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https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Genistein as an inducer of tumor cell differentiation: possible mechanisms of action

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Phytoestrogen interaction with estrogen receptors in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Genistein inhibits proliferation similarly in estrogen receptor-positive and negative human breast carcinoma cell lines characterized by P21WAF1/CIP1 induction, G2/M arrest, and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Infertility in Ewes caused by Prolonged Grazing on Oestrogenic Pastures: Oestrus, Fertilization and Cervical Mucus

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Mammalian lignan production from various foods

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Chemical studies of phytoestrogens and related compounds in dietary supplements: flax and chaparral

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Human metabolism of mammalian lignan precursors in raw and processed flaxseed

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Reduction of Serum Cholesterol and Hypercholesterolemic Atherosclerosis in Rabbits by Secoisolariciresinol Diglucoside Isolated From Flaxseed

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Lignans and flavonoids inhibit aromatase enzyme in human preadipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Aromatase and 17beta-hydroxysteroid dehydrogenase inhibition by flavonoids

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Antithyroid effects in vivo and in vitro of vitexin: a C-glucosylflavone in millet

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Antithyroid and goitrogenic effects of millet: role of C-glycosylflavones

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Flavonoids extracted from fonio millet (Digitaria exilis) reveal potent antithyroid properties

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

A urinary profile study of dietary phytoestrogens. The identification and mode of metabolism of new isoflavonoids

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

The variable metabolic response to dietary isoflavones in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Disposition of quercetin in man after single oral and intravenous doses

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Accumulation of (-)-epicatechin metabolites in rat plasma after oral administration and distribution of conjugation enzymes in rat tissues

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https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Quercetin is recovered in human plasma as conjugated derivatives which retain antioxidant properties

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Plasma and lipoprotein levels of tea catechins following repeated tea consumption.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Evidence for the interaction between (-)-epigallocatechin gallate and human plasma proteins fibronectin, fibrinogen, and histidine-rich glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Quercetin metabolites in plasma of rats fed diets containing rutin or quercetin

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Maternal and neonatal phytoestrogens in Japanese women during birth

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

The Causes of Cancer: Quantitative Estimates of Avoidable Risks of Cancer in the United States Today

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Mutagenicity of plant flavonoids: Structural requirements for mutagenic activity in Salmonella typhimurium

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Mutagenic Activity of Quercetin and Related Compounds

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Mutagenicity of plant flavonols in the Salmonella/mammalian microsome test: activation of flavonol glycosides by mixed glycosidases from rat cecal bacteria and other sources

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Genetic effects of the flavonols quercetin, kaempferol, and galangin on Chinese hamster ovary cells in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Genotoxicity of quercetin in the micronucleus assay in mouse bone marrow erythrocytes, human lymphocytes, V79 cell line and identification of kinetochore-containing (CREST staining) micronuclei in human lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Genetic toxicology of flavonoids: the role of metabolic conditions in the induction of reverse mutation, SOS functions and sister-chromatid exchanges

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Inhibition of mitochondrial respiration and production of toxic oxygen radicals by flavonoids. A structure-activity study

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Two-electron electrochemical oxidation of quercetin and kaempferol changes only the flavonoid C-ring

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Mechanism of adriamycin cardiotoxicity: evidence for oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Enzymatic defenses of the mouse heart against reactive oxygen metabolites: alterations produced by doxorubicin

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Involvement of superoxide in the interaction of 2,3-dichloro-1,4-naphthoquinone with mitochondrial membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

A redox cycling mechanism of action for 2,3-dichloro-1,4-naphthoquinone with mitochondrial membranes and the role of sulfhydryl groups

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Strand scission in DNA induced by quercetin and Cu(II): role of Cu(I) and oxygen free radicals

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Interactions of flavonoids, trace metals, and oxygen: nuclear DNA damage and lipid peroxidation induced by myricetin.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Pro-oxidant activity of flavonoids: effects on glutathione and glutathione S-transferase in isolated rat liver nuclei

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Oxygen activation during peroxidase catalysed metabolism of flavones or flavanones

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Glutathione-dependent generation of reactive oxygen species by the peroxidase-catalyzed redox cycling of flavonoids

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Metabolites of daidzein and genistein and their biological activities

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Effects of protein tyrosine kinase inhibitors with different modes of action on topoisomerase activity and death of IL-2-dependent CTLL-2 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Maternal diet and infant leukemia: A role for DNA topoisomerase II inhibitors?

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Maternal exposure to potential inhibitors of DNA topoisomerase II and infant leukemia (United States): a report from the Children's Cancer Group.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

High-performance liquid chromatographic analysis of phytoestrogens in soy protein preparations with ultraviolet, electrochemical and thermospray mass spectrometric detection

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Genistein suppresses mammary cancer in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Neonatal genistein chemoprevents mammary cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Anti-thyroid isoflavones from soybean: isolation, characterization, and mechanisms of action

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Porphyrin pi-cation and protein radicals in peroxidase catalysis and inhibition by anti-thyroid chemicals

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Breast and soy-formula feedings in early infancy and the prevalence of autoimmune thyroid disease in children

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Inhibition of thyroid peroxidase by dietary flavonoids

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Dietary effects on breast-cancer risk in Singapore

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Dietary habits and lung cancer risk among Chinese females in Hong Kong who never smoked

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

Intake of specific carotenoids and flavonoids and the risk of gastric cancer in Spain

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900304-X

7 January 2021

10.1016/S0891-5849(00)00304-X

Identifiers

DOI

1 reference

30 July 2017

1 reference

PubMed ID

11035267