The apoptotic pathway: a target for therapy in chronic lymphocytic leukemia (Q34057963)

30 July 2017

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title

The apoptotic pathway: a target for therapy in chronic lymphocytic leukemia (English)

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chronic lymphocytic leukemia

30 July 2017

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Bentley DP

1

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30 July 2017

Pepper CJ

series ordinal

2

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30 July 2017

publication date

1 September 2000

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30 July 2017

published in

Hematological Oncology

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30 July 2017

volume

18

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30 July 2017

issue

3

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30 July 2017

page(s)

87-98

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30 July 2017

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NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

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Bax directly induces release of cytochrome c from isolated mitochondria

21 January 2018

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Programmed cell death: the influence of CD40, CD95 (Fas or Apo-I) and their ligands

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p53: puzzle and paradigm

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DNA-dependent protein kinase acts upstream of p53 in response to DNA damage

21 January 2018

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Protein synthesis required to anchor a mutant p53 protein which is temperature-sensitive for nuclear transport

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p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

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Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1

21 January 2018

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Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA.

21 January 2018

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Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

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A peptide sequence from Bax that converts Bcl-2 into an activator of apoptosis

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Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity

21 January 2018

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Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

21 January 2018

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Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

21 January 2018

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Bcl-x(L) forms an ion channel in synthetic lipid membranes.

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Channel formation by antiapoptotic protein Bcl-2.

21 January 2018

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Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

21 January 2018

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Caspases: enemies within

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Bcl-2/Bax ratios in chronic lymphocytic leukaemia and their correlation with in vitro apoptosis and clinical resistance

21 January 2018

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Gene transfer of CD40-ligand induces autologous immune recognition of chronic lymphocytic leukemia B cells

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21 January 2018

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Bryostatin and CD40-ligand enhance apoptosis resistance and induce expression of cell survival genes in B-cell chronic lymphocytic leukaemia.

21 January 2018

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The inhibition of DNA synthesis in chronic lymphocytic leukaemia cells by chlorambucil in vitro

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Increased sensitivity of CLL-derived lymphocytes to apoptotic death activation by the proteasome-specific inhibitor lactacystin

21 January 2018

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Elevated levels of biologically active soluble CD40 ligand in the serum of patients with chronic lymphocytic leukaemia

21 January 2018

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Quantitative characterization and potential function of membrane Fas/APO-1 (CD95) receptors on leukaemic cells from chronic B and T lymphoid leukaemias

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Downregulation of the CD95 receptor and defect CD40-mediated signal transduction in B-chronic lymphocytic leukemia cells

21 January 2018

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Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia

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Regulation of clinical chemoresistance by bcl-2 and bax oncoproteins in B-cell chronic lymphocytic leukaemia

21 January 2018

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Chlorambucil resistance in B-cell chronic lymphocytic leukaemia is mediated through failed Bax induction and selection of high Bcl-2-expressing subclones

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Processing/activation of caspases, -3 and -7 and -8 but not caspase-2, in the induction of apoptosis in B-chronic lymphocytic leukemia cells

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Antisense-mediated suppression of Bcl-2 highlights its pivotal role in failed apoptosis in B-cell chronic lymphocytic leukaemia

21 January 2018

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BCL-2 antisense therapy in patients with non-Hodgkin lymphoma

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10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

21 January 2018

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DOI

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30 July 2017

1 reference