Molecular model of SARS coronavirus polymerase: implications for biochemical functions and drug design (Q34053804)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14654687%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

Molecular model of SARS coronavirus polymerase: implications for biochemical functions and drug design (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14654687%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

0 references

1 reference

RNA-directed RNA polymerase [SARS-Cov]

0 references

1 reference

5

1 reference

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21 December 2019

3

Susan Weiss

1 reference

21 December 2019

4

Eddy Arnold

1 reference

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21 December 2019

author name string

Xiang Xu

series ordinal

1

1 reference

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21 December 2019

Yunqing Liu

series ordinal

2

1 reference

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21 December 2019

Jianping Ding

series ordinal

6

1 reference

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21 December 2019

language of work or name

English

0 references

publication date

1 December 2003

1 reference

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21 December 2019

published in

Nucleic Acids Research

1 reference

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21 December 2019

volume

31

1 reference

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21 December 2019

issue

24

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21 December 2019

page(s)

7117-7130

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Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage

21 December 2019

cites work

1 reference

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Mechanisms and enzymes involved in SARS coronavirus genome expression

5 July 2018

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Crystallographic Identification of a Noncompetitive Inhibitor Binding Site on the Hepatitis C Virus NS5B RNA Polymerase Enzyme

5 July 2018

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A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity

5 July 2018

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The Genome sequence of the SARS-associated coronavirus

5 July 2018

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Characterization of a novel coronavirus associated with severe acute respiratory syndrome

5 July 2018

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Approaching a new era for hepatitis C virus therapy: inhibitors of the NS3-4A serine protease and the NS5B RNA-dependent RNA polymerase.

5 July 2018

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Coronavirus as a possible cause of severe acute respiratory syndrome

5 July 2018

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A novel coronavirus associated with severe acute respiratory syndrome

5 July 2018

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Identification of a novel coronavirus in patients with severe acute respiratory syndrome

5 July 2018

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A major outbreak of severe acute respiratory syndrome in Hong Kong

5 July 2018

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A cluster of cases of severe acute respiratory syndrome in Hong Kong.

5 July 2018

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Identification of severe acute respiratory syndrome in Canada

5 July 2018

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A structural and primary sequence comparison of the viral RNA-dependent RNA polymerases

5 July 2018

1 reference

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Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogs

5 July 2018

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RNA synthesis in a cage--structural studies of reovirus polymerase lambda3

5 July 2018

1 reference

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Identification and biological characterization of heterocyclic inhibitors of the hepatitis C virus RNA-dependent RNA polymerase

5 July 2018

1 reference

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Mechanism of action of ribavirin in the combination treatment of chronic HCV infection

5 July 2018

1 reference

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Structural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with Ribonucleotides

5 July 2018

1 reference

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A mutation in the primer grip region of HIV-1 reverse transcriptase that confers reduced fidelity of DNA synthesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

A mechanism for initiating RNA-dependent RNA polymerization

5 July 2018

1 reference

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Oligomeric structures of poliovirus polymerase are important for function

5 July 2018

1 reference

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Poliovirus RNA-dependent RNA polymerase (3Dpol): structural, biochemical, and biological analysis of conserved structural motifs A and B

5 July 2018

1 reference

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5 July 2018

1 reference

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Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

Touching the heart of HIV-1 drug resistance: the fingers close down on the dNTP at the polymerase active site

5 July 2018

1 reference

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ESPript: analysis of multiple sequence alignments in PostScript

5 July 2018

1 reference

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Expression of hepatitis C virus NS5B protein: characterization of its RNA polymerase activity and RNA binding

5 July 2018

1 reference

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Analysis of RNA-dependent RNA polymerase structure and function as guided by known polymerase structures and computer predictions of secondary structure

5 July 2018

1 reference

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Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution

5 July 2018

1 reference

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Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

5 July 2018

1 reference

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Structure of the RNA-dependent RNA polymerase of poliovirus

5 July 2018

1 reference

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Conferring RNA polymerase activity to a DNA polymerase: a single residue in reverse transcriptase controls substrate selection

5 July 2018

1 reference

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Crystal structures of 8-Cl and 9-Cl TIBO complexed with wild-type HIV-1 RT and 8-Cl TIBO complexed with the Tyr181Cys HIV-1 RT drug-resistant mutant

5 July 2018

1 reference

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Human immunodeficiency virus type 1 reverse transcriptase: role of Tyr115 in deoxynucleotide binding and misinsertion fidelity of DNA synthesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

PHD: predicting one-dimensional protein structure by profile-based neural networks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

Evaluation of comparative protein modeling by MODELLER

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

Prediction of protein secondary structure at better than 70% accuracy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

Redefining the goals of protein secondary structure prediction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor alpha-APA R 95845 at 2.8 A resolution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

High resolution structures of HIV-1 RT from four RT-inhibitor complexes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

Primary structural comparison of RNA-dependent polymerases from plant, animal and bacterial viruses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

Identification of four conserved motifs among the RNA-dependent polymerase encoding elements

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

An attempt to unify the structure of polymerases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

Improved methods for building protein models in electron density maps and the location of errors in these models

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

The phylogeny of RNA-dependent RNA polymerases of positive-strand RNA viruses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

Origin and evolution of retroelements based upon their reverse transcriptase sequences

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

Glycyrrhizin, an active component of liquorice roots, and replication of SARS-associated coronavirus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

Canonical 3'-deoxyribonucleotides as a chain terminator for HCV NS5B RNA-dependent RNA polymerase

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

Identification of N,N-disubstituted phenylalanines as a novel class of inhibitors of hepatitis C NS5B polymerase

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

The palm subdomain-based active site is internally permuted in viral RNA-dependent RNA polymerases of an ancient lineage

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

Structure-function relationships of the RNA-dependent RNA polymerase from poliovirus (3Dpol). A surface of the primary oligomerization domain functions in capsid precursor processing and VPg uridylylation.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

A novel mechanism to ensure terminal initiation by hepatitis C virus NS5B polymerase

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

2001 ASPET Otto Krayer Award Lecture. Molecular targets for antiviral agents

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291860

Lethal mutagenesis of HIV by mutagenic ribonucleoside analogs

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14654687

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKG916

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14654687%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14654687%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14654687%20AND%20SRC:MED&resulttype=core&format=json