A review of the genetic and related effects of 1,3-butadiene in rodents and humans (Q34053160)

30 July 2017

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title

A review of the genetic and related effects of 1,3-butadiene in rodents and humans (English)

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30 July 2017

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ChEBI release 2020-05-28

M A Jackson

1

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30 July 2017

H F Stack

series ordinal

2

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30 July 2017

J M Rice

series ordinal

3

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30 July 2017

M D Waters

series ordinal

4

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30 July 2017

language of work or name

English

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publication date

1 October 2000

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30 July 2017

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30 July 2017

463

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30 July 2017

3

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30 July 2017

181-213

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Toxicology and epidemiology of 1,3-butadiene

30 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Mortality among workers at a butadiene facility

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Mortality of a cohort of workers in the styrene-butadiene polymer manufacturing industry (1943-1982).

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Environmental epidemiologic investigation of the styrene-butadiene rubber industry

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Lymphohematopoietic cancer in styrene-butadiene polymerization workers

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

A follow-up study of synthetic rubber workers

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Leukemia and cumulative exposure to butadiene, styrene and benzene among workers in the synthetic rubber industry.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Mortality update of butadiene production workers

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Inhalation toxicity studies with 1,3-butadiene. 3. Two year toxicity/carcinogenicity study in rats

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Inhalation toxicity and carcinogenicity of 1,3-butadiene in Sprague-Dawley rats

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Use of computerized data listings and activity profiles of genetic and related effects in the review of 195 compounds

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Biological activation of 1,3-butadiene to vinyl oxirane by rat liver microsomes and expiration of the reactive metabolite by exposed rats

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Comparison of the biotransformation of 1,3-butadiene and its metabolite, butadiene monoepoxide, by hepatic and pulmonary tissues from humans, rats and mice

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Human liver microsomes are efficient catalysts of 1,3-butadiene oxidation: evidence for major roles by cytochromes P450 2A6 and 2E1.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Comparison of blood concentrations of 1,3-butadiene and butadiene epoxides in mice and rats exposed to 1,3-butadiene by inhalation.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

High concentrations of butadiene epoxides in livers and lungs of mice compared to rats exposed to 1,3-butadiene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Species differences in the formation of butadiene monoxide from 1,3-butadiene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Disposition of butadiene monoepoxide and butadiene diepoxide in various tissues of rats and mice following a low-level inhalation exposure to 1,3-butadiene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Gender differences in the metabolism of 1, 3-butadiene in Sprague-Dawley rats following a low level inhalation exposure

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

The role of hydrolysis in the detoxification of 1,2:3,4-diepoxybutane by human, rat, and mouse liver and lung in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Hepatic microsomal metabolism of 1,3-butadiene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Oxidation of 1,2-epoxy-3-butene to 1,2:3,4-diepoxybutane by cDNA-expressed human cytochromes P450 2E1 and 3A4 and human, mouse and rat liver microsomes

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Characterization of urinary metabolites from Sprague-Dawley rats and B6C3F1 mice exposed to [1,2,3,4-13C]butadiene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Quantitative and qualitative differences in the metabolism of 14C-1,3-butadiene in rats and mice: relevance to cancer susceptibility

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Species differences in urinary butadiene metabolites: comparisons of metabolite ratios between mice, rats, and humans

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Abnormal DNA repair activities in lymphocytes of workers exposed to 1,3-butadiene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Comparison of the disposition of butadiene epoxides in Sprague-Dawley rats and B6C3F1 mice following a single and repeated exposures to 1,3-butadiene via inhalation

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Molecular dosimetry of N-7 guanine adduct formation in mice and rats exposed to 1,3-butadiene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Identification of novel metabolites of butadiene monoepoxide in rats and mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Haemoglobin adducts of epoxybutanediol from exposure to 1,3-butadiene or butadiene epoxides

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Genotoxic markers among butadiene polymer workers in China.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Glutathione conjugation of 1,2:3,4- diepoxybutane in human liver and rat and mouse liver and lung in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Enzyme specific kinetics of 1,2-epoxybutene-3 in microsomes and cytosol from livers of mouse, rat, and man

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

1,3-Butadiene: linking metabolism, dosimetry, and mutation induction

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

A physiological toxicokinetic model for 1,3-butadiene in rodents and man: blood concentrations of 1,3-butadiene, its metabolically formed epoxides, and of haemoglobin adducts--relevance of glutathione depletion.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

A physiologically based pharmacokinetic model for butadiene and its metabolite butadiene monoxide in rat and mouse and its significance for risk extrapolation.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Species differences in the production and clearance of 1,3-butadiene metabolites: a mechanistic model indicates predominantly physiological, not biochemical, control.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

In vivo metabolism of butadiene by mice and rats: a comparison of physiological model predictions and experimental data

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Physiologically based pharmacokinetic modeling of 1,3-butadiene, 1,2- epoxy-3-butene, and 1,2:3,4-diepoxybutane toxicokinetics in mice and rats

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Haemoglobin adducts as biomarkers of occupational exposure to 1,3-butadiene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Epoxybutene-hemoglobin adducts in rats and mice: dose response for formation and persistence during and following long-term low-level exposure to butadiene.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Mutagenic potential of guanine N2 adducts of butadiene mono- and diolepoxide

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Butadiene diolepoxide- and diepoxybutane-derived DNA adducts at N7-guanine: a high occurrence of diolepoxide-derived adducts in mouse lung after 1,3-butadiene exposure

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Persistence of N7-(2,3,4-trihydroxybutyl)guanine adducts in the livers of mice and rats exposed to 1,3-butadiene.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Human DNA adducts of 1,3-butadiene, an important environmental carcinogen

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

DNA adducts in mouse testis and lung after inhalation exposure to 1,3-butadiene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Biological formation of the 1,3-butadiene DNA adducts 7-N-(2-hydroxy-3-buten-1-yl)guanine, 7-N-(1-hydroxy-3-buten-2-yl)guanine and 7-N-(2,3,4-trihydroxy-butyl)guanine

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Species differences in DNA damage by butadiene: role of diepoxybutane

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Alkylation of nuclear proteins and DNA after exposure of rats and mice to [1,4-14C]1,3-butadiene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

32P-postlabelling of N6-adenine adducts of epoxybutanediol in vivo after 1,3-butadiene exposure

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

32P-postlabelling/HPLC assay reveals an enantioselective adduct formation in N7 guanine residues in vivo after 1,3-butadiene inhalation exposure.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Mutagenicity of 1,3-butadiene at the Hprt locus of T-lymphocytes following inhalation exposures of female mice and rats.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Comparison of the mutagenic potency of 1,3-butadiene at the hprt locus of T-lymphocytes following inhalation exposure of female B6C3F1 mice and F344 rats

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Comparison of induction of hprt mutations by 1,3-butadiene and/or its metabolites 1,2-epoxybutene and 1,2,3,4-diepoxybutane in lymphocytes from spleen of adult male mice and rats in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Development of a cloning assay with high cloning efficiency to detect induction of 6-thioguanine-resistant lymphocytes in spleen of adult mice following in vivo inhalation exposure to 1,3-butadiene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Mutagenicity of 1,3-butadiene inhalation in somatic and germinal cells of mice

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

hprt mutation frequency among workers exposed to 1,3-butadiene in China.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Biological effect monitoring in industrial workers from the Czech Republic exposed to low levels of butadiene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Biological monitoring for mutagenic effects of occupational exposure to butadiene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

hprt mutant lymphocyte frequencies in workers at a 1,3-butadiene production plant

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Comparative cytogenetic analysis of bone marrow damage induced in male B6C3F1 mice by multiple exposures to gaseous 1,3-butadiene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Chromosomal aberrations, sister-chromatid exchanges, cells with high frequency of SCE, micronuclei and comet assay parameters in 1, 3-butadiene-exposed workers

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Sister-chromatid exchanges, glutathione s-transferase theta deletion and cytogenic sensitivity to diepoxybutane in lymphocytes from butadiene monomer production workers

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Human cytogenetic biomonitoring of occupational exposure to 1,3-butadiene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Induction of micronuclei in peripheral blood and bone marrow erythrocytes of rats and mice exposed to 1,3-butadiene by inhalation

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Genotoxic activity of 1,3-butadiene and nitrogen dioxide and their photochemical reaction products in Drosophila and in the mouse bone marrow micronucleus assay.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

1,3-Butadiene: induction of micronucleated erythrocytes in the peripheral blood of B6C3F1 mice exposed by inhalation for 13 weeks

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Micronucleus induction in somatic cells of mice as evaluated after 1,3-butadiene inhalation

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Evaluation and characterization of micronuclei in early spermatids of mice exposed to 1,3-butadiene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Chromosome aberrations in mouse bone marrow cells following in vivo exposure to 1,3-butadiene.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Reproductive toxicity of 1,3-butadiene in the mouse: cytogenetic analysis of chromosome aberrations in first-cleavage embryos and flow cytometric evaluation of spermatogonial cell killing

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Dose response study for 1,3-butadiene-induced dominant lethal mutations and heritable translocations in germs cells of male mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

A comparison of male-mediated effects in rats and mice exposed to 1,3-butadiene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Genetic effects of 1,3-butadiene on the mouse testis

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Overview of reproductive and developmental toxicity studies of 1,3-butadiene in rodents

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Heritable translocations induced by inhalation exposure of male mice to 1,3-butadiene.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Evaluation of DNA damage by alkaline elution technique after inhalation exposure of rats and mice to 1,3-butadiene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Detection of diepoxybutane-induced DNA-DNA crosslinks by cesium trifluoracetate (CsTFA) density-gradient centrifugation

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

DNA damage in lung cells in vivo and in vitro by 1,3-butadiene and nitrogen dioxide and their photochemical reaction products

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Comparison of the mutations at Hprt exon 3 of T-lymphocytes from B6C3F1 mice and F344 rats exposed by inhalation to 1,3-butadiene or the racemic mixture of 1,2:3,4-diepoxybutane

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Increased frequency of mutations at A:T base pairs in the bone marrow of B6C3F1 lacI transgenic mice exposed to 1,3-butadiene.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

The in vivo mutagenicity and mutational spectrum at the lacI transgene recovered from the spleens of B6C3F1 lacI transgenic mice following a 4-week inhalation exposure to 1,3-butadiene.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Determination of mutagenicity in tissues of transgenic mice following exposure to 1,3-butadiene and N-ethyl-N-nitrosourea

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

The genotype of the human cancer cell: implications for risk analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Antioncogenes and human cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Molecular and genetic toxicology of 1,3-butadiene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Activation of H-ras is prevalent in 1,3-butadiene-induced and spontaneously occurring murine Harderian gland tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

The molecular pathophysiology of myeloid leukaemias: Ras revisited.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Levels of ras oncoproteins in human plasma from 1,3-butadiene-exposed workers and controls

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Assessment of exposure to butadiene in the process industry

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Mutagenicity of the racemic mixtures of butadiene monoepoxide and butadiene diepoxide at the Hprt locus of T-lymphocytes following inhalation exposures of female mice and rats

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Mutagenicity of butadiene and its epoxide metabolites: II. Mutational spectra of butadiene, 1,2-epoxybutene and diepoxybutane at the hprt locus in splenic T cells from exposed B6C3F1 mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Characterization of hprt mutations following 1,2-epoxy-3-butene exposure of human TK6 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Sister chromatid exchange and chromosome aberration analyses in mice after in vivo exposure to acrylonitrile, styrene, or butadiene monoxide

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Comparison of cytogenetic effects of 3,4-epoxy-1-butene and 1,2:3, 4-diepoxybutane in mouse, rat and human lymphocytes following in vitro G0 exposures.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Induction of sister chromatid exchange by 1,2-epoxy-3-butene in cultured human lymphocytes: influence of GSTT1 genotype

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Induction of sister chromatid exchange by 3,4-expoxybutane-1,2-diol in cultured human lymphocytes of different GSTT1 and GSTM1 genotypes

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Influence of GSTM1 genotype on sister chromatid exchange induction by styrene-7,8-oxide and 1,2-epoxy-3-butene in cultured human lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

1,3-Butadiene and its epoxides induce sister-chromatid exchanges in human lymphocytes in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Somatic and germ cell effects in rats and mice after treatment with 1,3-butadiene and its metabolites, 1,2-epoxybutene and 1,2,3,4-diepoxybutane

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

In vitro and in vivo mutagenicity of the butadiene metabolites butadiene diolepoxide, butadiene monoepoxide and diepoxybutane.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Micronucleus induction in germ and somatic cells of the mouse after exposure to the butadiene metabolites diepoxybutane and epoxybutene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Germ cell mutagenicity of three metabolites of 1,3-butadiene in the rat: induction of spermatid micronuclei by butadiene mono-, di-, and diolepoxides in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Induction of chromosome-specific aneuploidy and micronuclei in human lymphocytes by metabolites of 1,3-butadiene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Discrimination between genotoxicity and cytotoxicity for the induction of DNA double-strand breaks in cells treated with aldehydes and diepoxides

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

32P-postlabeling of 1,3-butadiene and 4-vinyl-1-cyclohexene metabolite-DNA adducts: in vitro and in vivo applications

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Monophosphate 32P-postlabeling assay of DNA adducts from 1,2:3,4-diepoxybutane, the most genotoxic metabolite of 1,3-butadiene: in vitro methodological studies and in vivo dosimetry

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Analysis of hprt mutations occurring in human TK6 lymphoblastoid cells following exposure to 1,2,3,4-diepoxybutane

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Chromosomal abnormalities and sister-chromatid exchange in bone marrow cells of mice and Chinese hamsters after inhalation and intraperitoneal administration: I. Diepoxybutane.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Induction and rapid repair of sister-chromatid exchanges in multiple murine tissues in vivo by diepoxybutane

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Influence of erythrocyte glutathione S-transferase T1 on sister chromatid exchanges induced by diepoxybutane in cultured human lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Modulating factors of individual sensitivity to diepoxybutane: sister chromatid exchanges induced in vitro in human lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Role of GSTT1 and GSTM1 genotypes in determining individual sensitivity to sister chromatid exchange induction by diepoxybutane in cultured human lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Effect of red cells and plasma blood in determining individual lymphocytes sensitivity to diepoxybutane assessed by in vitro induced sister chromatid exchanges

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Bimodal distribution of sensitivity to SCE induction by diepoxybutane in human lymphocytes. I. Correlation with chromosomal aberrations

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Failure of diepoxybutane to enhance sister chromatid exchange levels in Fanconi's anemia patients and heterozygotes

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Differential induction of sister chromatid exchange by chemical carcinogens in lymphocytes cultured from patients with solid tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Clastogenicity of diepoxybutane in bone marrow cells and male germ cells of mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

GSTT1-dependent induction of centromere-negative and -positive micronuclei by l,2:3,4-diepoxybutane in cultured human lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Fanconi's anemia: a cytogenetic study on lymphocyte and bone marrow cultures utilizing 1,2:3,4-diepoxybutane

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

The cytogenetic response of Fanconi’s anemia lymphoblastoid cell lines to various clastogens

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Susceptibility of Fanconi's anaemia fibroblasts to chromosome damage by carcinogens

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Genetic effects of 1,3-butadiene and associated risk for heritable damage.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Meeting report of the EC/US workshop on genetic risk assessment: "human genetic risks from exposure to chemicals, focusing on the feasibility of a parallelogram approach"

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Molecular analysis of lacI mutants from transgenic fibroblasts exposed to 1,2-epoxybutene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

The butadiene metabolite, 1,2:3,4-diepoxybutane, induces micronuclei but is only weakly mutagenic at lacI in the Big Blue Rat2 lacI transgenic cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Synthesis, characterization, and in vitro quantitation of N-7-guanine adducts of diepoxybutane

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900056-9

7 January 2021

10.1016/S1383-5742(00)00056-9

Identifiers

DOI

1 reference

30 July 2017

1 reference